Homology
BLAST of MS001195.1 vs. NCBI nr
Match:
XP_022131733.1 (protein cereblon isoform X3 [Momordica charantia] >XP_022131734.1 protein cereblon isoform X4 [Momordica charantia])
HSP 1 Score: 1049.7 bits (2713), Expect = 8.9e-303
Identity = 537/543 (98.90%), Postives = 539/543 (99.26%), Query Frame = 0
Query: 1 MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS 60
MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS
Sbjct: 1 MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS 60
Query: 61 LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIE 120
LASLHTYLGEVED+HHRMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQANFIAAIE
Sbjct: 61 LASLHTYLGEVEDSHHRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQANFIAAIE 120
Query: 121 RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL 180
RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL
Sbjct: 121 RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL 180
Query: 181 RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFT 240
RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLS ALASYTSCS QFT
Sbjct: 181 RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSCALASYTSCSRQFT 240
Query: 241 SRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS 300
SRDEE DSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS
Sbjct: 241 SRDEEVDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS 300
Query: 301 DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW 360
DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW
Sbjct: 301 DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW 360
Query: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420
VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG
Sbjct: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420
Query: 421 ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR 480
ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR
Sbjct: 421 ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR 480
Query: 481 ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540
ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD
Sbjct: 481 ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540
Query: 541 ATR 544
ATR
Sbjct: 541 ATR 542
BLAST of MS001195.1 vs. NCBI nr
Match:
XP_022131731.1 (protein cereblon isoform X1 [Momordica charantia] >XP_022131732.1 protein cereblon isoform X2 [Momordica charantia])
HSP 1 Score: 1045.0 bits (2701), Expect = 2.2e-301
Identity = 537/544 (98.71%), Postives = 539/544 (99.08%), Query Frame = 0
Query: 1 MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPI-HGHGGVETFAEFTFNS 60
MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPI HGHGGVETFAEFTFNS
Sbjct: 1 MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPISHGHGGVETFAEFTFNS 60
Query: 61 SLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAI 120
SLASLHTYLGEVED+HHRMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQANFIAAI
Sbjct: 61 SLASLHTYLGEVEDSHHRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQANFIAAI 120
Query: 121 ERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFR 180
ERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFR
Sbjct: 121 ERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFR 180
Query: 181 LRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQF 240
LRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLS ALASYTSCS QF
Sbjct: 181 LRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSCALASYTSCSRQF 240
Query: 241 TSRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLND 300
TSRDEE DSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLND
Sbjct: 241 TSRDEEVDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLND 300
Query: 301 SDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPY 360
SDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPY
Sbjct: 301 SDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPY 360
Query: 361 WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID 420
WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID
Sbjct: 361 WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID 420
Query: 421 GISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFN 480
GISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFN
Sbjct: 421 GISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFN 480
Query: 481 RANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA 540
RANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA
Sbjct: 481 RANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA 540
Query: 541 DATR 544
DATR
Sbjct: 541 DATR 543
BLAST of MS001195.1 vs. NCBI nr
Match:
XP_038885492.1 (protein cereblon isoform X2 [Benincasa hispida])
HSP 1 Score: 967.6 bits (2500), Expect = 4.4e-278
Identity = 495/543 (91.16%), Postives = 516/543 (95.03%), Query Frame = 0
Query: 1 MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS 60
MED+R+LERERHQIEQILQLDNEELQVEEVDYL DSDDD D I+GHGG E FAEFTFNS
Sbjct: 1 MEDQRLLERERHQIEQILQLDNEELQVEEVDYLHDSDDDGDAINGHGGTEAFAEFTFNSY 60
Query: 61 LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIE 120
LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQ+NFIAAIE
Sbjct: 61 LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQSNFIAAIE 120
Query: 121 RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL 180
RVLTHFDTPNTIGVVHVS+DSDNE+L FAN+GTTAEIRQFRRLEDGS+NVL RGKQRFRL
Sbjct: 121 RVLTHFDTPNTIGVVHVSVDSDNERLRFANVGTTAEIRQFRRLEDGSLNVLARGKQRFRL 180
Query: 181 RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFT 240
RRRWID EGVPCGEVQIIQEDLPLRTPRDAFG+LAPRS+VQRHSLS ALASYTSCS FT
Sbjct: 181 RRRWIDVEGVPCGEVQIIQEDLPLRTPRDAFGDLAPRSTVQRHSLSCALASYTSCSRSFT 240
Query: 241 SRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS 300
SRD EDDSASNSEESFERELSLRERKIHQAAIDS+ES SDEEISGSE+EHQHAMSHLNDS
Sbjct: 241 SRD-EDDSASNSEESFERELSLRERKIHQAAIDSSESCSDEEISGSEAEHQHAMSHLNDS 300
Query: 301 DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW 360
DS+GSM SD EKENEKPA D GKSSTSARESS+RKEL+RC+RNSSFN MH SKAFWPYW
Sbjct: 301 DSVGSMHSDCEKENEKPASDIGKSSTSARESSERKELKRCQRNSSFNLMHRASKAFWPYW 360
Query: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420
VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG
Sbjct: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420
Query: 421 ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR 480
ISYRLRRE+ELLKSIDIIQCKNCKTVIAKRSDMLVMS++GPLGAYVNPHGYVHEI T R
Sbjct: 421 ISYRLRREIELLKSIDIIQCKNCKTVIAKRSDMLVMSTEGPLGAYVNPHGYVHEIMTLYR 480
Query: 481 ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540
ANG+ALRGRA TEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD
Sbjct: 481 ANGLALRGRAETEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540
Query: 541 ATR 544
TR
Sbjct: 541 VTR 541
BLAST of MS001195.1 vs. NCBI nr
Match:
XP_038885491.1 (protein cereblon isoform X1 [Benincasa hispida])
HSP 1 Score: 963.0 bits (2488), Expect = 1.1e-276
Identity = 495/544 (90.99%), Postives = 516/544 (94.85%), Query Frame = 0
Query: 1 MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPI-HGHGGVETFAEFTFNS 60
MED+R+LERERHQIEQILQLDNEELQVEEVDYL DSDDD D I +GHGG E FAEFTFNS
Sbjct: 1 MEDQRLLERERHQIEQILQLDNEELQVEEVDYLHDSDDDGDAISNGHGGTEAFAEFTFNS 60
Query: 61 SLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAI 120
LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQ+NFIAAI
Sbjct: 61 YLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQSNFIAAI 120
Query: 121 ERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFR 180
ERVLTHFDTPNTIGVVHVS+DSDNE+L FAN+GTTAEIRQFRRLEDGS+NVL RGKQRFR
Sbjct: 121 ERVLTHFDTPNTIGVVHVSVDSDNERLRFANVGTTAEIRQFRRLEDGSLNVLARGKQRFR 180
Query: 181 LRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQF 240
LRRRWID EGVPCGEVQIIQEDLPLRTPRDAFG+LAPRS+VQRHSLS ALASYTSCS F
Sbjct: 181 LRRRWIDVEGVPCGEVQIIQEDLPLRTPRDAFGDLAPRSTVQRHSLSCALASYTSCSRSF 240
Query: 241 TSRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLND 300
TSRD EDDSASNSEESFERELSLRERKIHQAAIDS+ES SDEEISGSE+EHQHAMSHLND
Sbjct: 241 TSRD-EDDSASNSEESFERELSLRERKIHQAAIDSSESCSDEEISGSEAEHQHAMSHLND 300
Query: 301 SDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPY 360
SDS+GSM SD EKENEKPA D GKSSTSARESS+RKEL+RC+RNSSFN MH SKAFWPY
Sbjct: 301 SDSVGSMHSDCEKENEKPASDIGKSSTSARESSERKELKRCQRNSSFNLMHRASKAFWPY 360
Query: 361 WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID 420
WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID
Sbjct: 361 WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID 420
Query: 421 GISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFN 480
GISYRLRRE+ELLKSIDIIQCKNCKTVIAKRSDMLVMS++GPLGAYVNPHGYVHEI T
Sbjct: 421 GISYRLRREIELLKSIDIIQCKNCKTVIAKRSDMLVMSTEGPLGAYVNPHGYVHEIMTLY 480
Query: 481 RANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA 540
RANG+ALRGRA TEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA
Sbjct: 481 RANGLALRGRAETEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA 540
Query: 541 DATR 544
D TR
Sbjct: 541 DVTR 542
BLAST of MS001195.1 vs. NCBI nr
Match:
KAG6585376.1 (Protein cereblon, partial [Cucurbita argyrosperma subsp. sororia])
HSP 1 Score: 959.5 bits (2479), Expect = 1.2e-275
Identity = 486/543 (89.50%), Postives = 515/543 (94.84%), Query Frame = 0
Query: 1 MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS 60
MED+R+L+ ERHQIEQILQLDNEELQVEEVDYLP+SDDDRD I+ HGG E FAEFTFNSS
Sbjct: 1 MEDQRLLDNERHQIEQILQLDNEELQVEEVDYLPESDDDRDAINDHGGYEAFAEFTFNSS 60
Query: 61 LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIE 120
LASLHTYLGEVEDAHHRMAFLDGGAILN+PVFYLEG+ VLFPEATLPLRVIQ+NFIAAIE
Sbjct: 61 LASLHTYLGEVEDAHHRMAFLDGGAILNIPVFYLEGV-VLFPEATLPLRVIQSNFIAAIE 120
Query: 121 RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL 180
RVLTHFDTPNTIGVVHVS+DS +++L FANIGTTAEIRQFRRLEDGS+NVL RGKQRFRL
Sbjct: 121 RVLTHFDTPNTIGVVHVSVDSGSDRLRFANIGTTAEIRQFRRLEDGSLNVLARGKQRFRL 180
Query: 181 RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFT 240
RRRWID EGVPCGEVQIIQEDLPLRTPRDAFG+LAPR+++QRHSLS ALASYTSCS FT
Sbjct: 181 RRRWIDVEGVPCGEVQIIQEDLPLRTPRDAFGDLAPRNTIQRHSLSCALASYTSCSRPFT 240
Query: 241 SRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS 300
SRDEEDDSASNSEESFERELSLRERKIHQAAI S+ES SDEEISGSE+EHQHAMSH NDS
Sbjct: 241 SRDEEDDSASNSEESFERELSLRERKIHQAAIGSSESCSDEEISGSEAEHQHAMSHQNDS 300
Query: 301 DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW 360
DSLG + SDYEKE+EKP+PD GKSSTSA++SS+RKE + CRRNSSFN MHGVSKAF PYW
Sbjct: 301 DSLGFLHSDYEKESEKPSPDIGKSSTSAKDSSERKEFKGCRRNSSFNHMHGVSKAFLPYW 360
Query: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420
VYSMYDSYCLAQKAAAMWKQIVG PNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG
Sbjct: 361 VYSMYDSYCLAQKAAAMWKQIVGAPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420
Query: 421 ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR 480
ISYRLRRE+ELLKSID+IQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEI T R
Sbjct: 421 ISYRLRREIELLKSIDLIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEIMTLYR 480
Query: 481 ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540
ANG+ALRGRA TEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD
Sbjct: 481 ANGLALRGRAETEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540
Query: 541 ATR 544
ATR
Sbjct: 541 ATR 542
BLAST of MS001195.1 vs. ExPASy Swiss-Prot
Match:
Q68EH9 (Protein cereblon OS=Danio rerio OX=7955 GN=crbn PE=1 SV=1)
HSP 1 Score: 173.3 bits (438), Expect = 7.4e-42
Identity = 142/525 (27.05%), Postives = 220/525 (41.90%), Query Frame = 0
Query: 18 LQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSSLASLHTYLGEVEDAHHR 77
LQL E + EE D + D D VE + F++SL + H YLG + H
Sbjct: 5 LQLLPENEEEEEDDMETEDRDGED-------VEKPSIINFDTSLPTSHAYLGSDMEEFHG 64
Query: 78 MAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIERVLTHFDTPNTIGVVHV 137
D ++ NLPV + +L P TLPL++ + ++ +++ T V+
Sbjct: 65 RTLHDEDSVQNLPVLPHVAL-ILIPGQTLPLQLFRPQEVSMFRNLVSQ---DRTFAVLAH 124
Query: 138 SLDSDNEKLHFANIGTTAEIRQFRRLED---GSINVLTRGKQRFRLRRRWIDAEGVPCGE 197
S D + A GTTAEI FR ++ ++ + G+QRFR+ A+G+ +
Sbjct: 125 SPDPSGTETK-AEFGTTAEIYAFREEQEYGIETVKIKAVGRQRFRVHDIRTQADGIRQAK 184
Query: 198 VQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFTSRDEEDDSASNSEE 257
VQI+ E + L P C+ QF R
Sbjct: 185 VQILPERI-LPDP--------------------------LCALQFLPR------------ 244
Query: 258 SFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDSDSLGSMQSDYEKEN 317
H H
Sbjct: 245 ----------------------------------LHTH---------------------- 304
Query: 318 EKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYWVYSMYDSYCLAQKA 377
+P T + T+ + +RC +N +H S WP WVYS+YDS L +
Sbjct: 305 ---SPQTKHTQTTPPQ-------KRCSQNYRQKKLHCASMTSWPPWVYSLYDSKTLMSRV 364
Query: 378 AAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDGISYRLRREVELLKS 437
+ + NP S+ +A+ +P+ ++ R +LL+I RLR E++++
Sbjct: 365 KKQLHEWDENLKDESLPTNPTDFSYRVAACLPIDDALRLQLLKIGSAIQRLRCELDIMDR 412
Query: 438 IDIIQCKNCK-TVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNRANGIALRGRAATE 497
+ CK C+ T I ++++ +S GP+ AYVNPHGYVHE T +A+ + L GR +T
Sbjct: 425 CTSLCCKQCQDTEITSKNEIFSLSLYGPMAAYVNPHGYVHETLTVYKASNLNLIGRPSTL 412
Query: 498 YSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQL 539
+SWFPGYAWTI+ C TC + +GW F+A ++L P FWG+ S L
Sbjct: 485 HSWFPGYAWTIAQCRTCSSHMGWKFSAVKKDLSPPRFWGLTRSAL 412
BLAST of MS001195.1 vs. ExPASy Swiss-Prot
Match:
Q0P564 (Protein cereblon OS=Bos taurus OX=9913 GN=CRBN PE=2 SV=1)
HSP 1 Score: 164.1 bits (414), Expect = 4.5e-39
Identity = 135/523 (25.81%), Postives = 223/523 (42.64%), Query Frame = 0
Query: 20 LDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSSLASLHTYLGEVEDAHHRMA 79
L EE + +E++ + D+++P + F++SL + HTYLG + H
Sbjct: 21 LPAEEEEEDEIEMEVEDQDNKEPKKPN-------IINFDTSLPTSHTYLGSDMEEFHGRT 80
Query: 80 FLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIERVLTHFDTPNTIGVVHVSL 139
D + +PV + + L P TLPL++ ++ + ++ T V+ S
Sbjct: 81 LHDDDSCPVIPVL-PQVVMTLIPGQTLPLQLFSPQEVSMVRNLI---QKDRTFAVLAYSN 140
Query: 140 DSDNEKLHFANIGTTAEIRQFRRLEDGSINVL---TRGKQRFRLRRRWIDAEGVPCGEVQ 199
+ E A GTTAEI +R +D I V+ G+QRF++ ++G+ +VQ
Sbjct: 141 VQERE----AQFGTTAEIYAYREEQDFGIEVVKVKAIGRQRFKVLEIRTQSDGIQQAKVQ 200
Query: 200 IIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFTSRDEEDDSASNSEESF 259
I+ E + T S+VQ SL++ F S+ S+
Sbjct: 201 ILPECVLPST----------MSAVQLESLNKCRI--------FPSK----------PVSW 260
Query: 260 ERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDSDSLGSMQSDYEKENEK 319
E + S + + +Q
Sbjct: 261 EDQCSYKWWQKYQ----------------------------------------------- 320
Query: 320 PAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYWVYSMYDSYCLAQKAAA 379
KRK H + WP W+YS+YD+ L +
Sbjct: 321 ----------------KRK-------------FHCANLTSWPRWLYSLYDAETLMDRIKK 380
Query: 380 MWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDGISYRLRREVELLKSID 439
++ D NP S+ +A+ +P+ + R +LL+I RLR E++++
Sbjct: 381 QLREWDENLKEDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCT 424
Query: 440 IIQCKNC-KTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNRANGIALRGRAATEYS 499
+ CK C +T I ++++ +S GP+ AYVNPHGYVHE T +A+ + L GR +T++S
Sbjct: 441 SLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKASNLNLIGRPSTDHS 424
Query: 500 WFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQL 539
WFPGYAWTI+ C C + +GW FTAT +++ P+ FWG+ S L
Sbjct: 501 WFPGYAWTIAQCRICASHIGWKFTATKKDMSPQKFWGLTRSAL 424
BLAST of MS001195.1 vs. ExPASy Swiss-Prot
Match:
Q96SW2 (Protein cereblon OS=Homo sapiens OX=9606 GN=CRBN PE=1 SV=1)
HSP 1 Score: 163.7 bits (413), Expect = 5.8e-39
Identity = 127/488 (26.02%), Postives = 207/488 (42.42%), Query Frame = 0
Query: 57 FNSSLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFI 116
F++SL + HTYLG + H D + +PV + + +L P TLPL++ +
Sbjct: 49 FDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVL-PQVMMILIPGQTLPLQLFHPQEV 108
Query: 117 AAIERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVL---TR 176
+ + ++ T V+ S + E A GTTAEI +R +D I ++
Sbjct: 109 SMVRNLI---QKDRTFAVLAYSNVQERE----AQFGTTAEIYAYREEQDFGIEIVKVKAI 168
Query: 177 GKQRFRLRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYT 236
G+QRF++ ++G+ +VQI+ E + T S+VQ SL++
Sbjct: 169 GRQRFKVLELRTQSDGIQQAKVQILPECVLPST----------MSAVQLESLNKCQI--- 228
Query: 237 SCSGQFTSR--DEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQ 296
F S+ ED + + +++ RK H A + S
Sbjct: 229 -----FPSKPVSREDQCSYKWWQKYQK------RKFHCANLTS----------------- 288
Query: 297 HAMSHLNDSDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHG 356
Sbjct: 289 ------------------------------------------------------------ 348
Query: 357 VSKAFWPYWVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSEST 416
WP W+YS+YD+ L + ++ D NP S+ +A+ +P+ +
Sbjct: 349 -----WPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVL 408
Query: 417 RQELLEIDGISYRLRREVELLKSIDIIQCKNC-KTVIAKRSDMLVMSSDGPLGAYVNPHG 476
R +LL+I RLR E++++ + CK C +T I ++++ +S GP+ AYVNPHG
Sbjct: 409 RIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHG 422
Query: 477 YVHEITTFNRANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSF 536
YVHE T +A + L GR +TE+SWFPGYAWT++ C C + +GW FTAT +++ P+ F
Sbjct: 469 YVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKF 422
Query: 537 WGIRSSQL 539
WG+ S L
Sbjct: 529 WGLTRSAL 422
BLAST of MS001195.1 vs. ExPASy Swiss-Prot
Match:
Q5R6Y2 (Protein cereblon OS=Pongo abelii OX=9601 GN=CRBN PE=2 SV=1)
HSP 1 Score: 162.5 bits (410), Expect = 1.3e-38
Identity = 126/486 (25.93%), Postives = 208/486 (42.80%), Query Frame = 0
Query: 57 FNSSLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFI 116
F++SL + HTYLG + H D + +PV + + +L P TLPL++ +
Sbjct: 36 FDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVL-PQVMMILIPGQTLPLQLFHPQEV 95
Query: 117 AAIERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVL---TR 176
+ + ++ T V+ S + E A GTTAEI +R +D I ++
Sbjct: 96 SMVRNLI---QKDRTFAVLAYSNIQERE----AQFGTTAEIYAYREEQDFGIEIVKVKAI 155
Query: 177 GKQRFRLRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYT 236
G+QRF++ ++G+ +VQI+ E + T S+VQ SL++
Sbjct: 156 GRQRFKVLELRTQSDGIQQAKVQILPECVLPST----------MSAVQLESLNKC----Q 215
Query: 237 SCSGQFTSRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHA 296
+ SR+++ S++ ++RK H A + S
Sbjct: 216 IFPPKPVSREDQC--------SYKWWQKYQKRKFHCANLTS------------------- 275
Query: 297 MSHLNDSDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVS 356
Sbjct: 276 ------------------------------------------------------------ 335
Query: 357 KAFWPYWVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQ 416
WP W+YS+YD+ L + ++ D NP S+ +A+ +P+ + R
Sbjct: 336 ---WPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRI 395
Query: 417 ELLEIDGISYRLRREVELLKSIDIIQCKNC-KTVIAKRSDMLVMSSDGPLGAYVNPHGYV 476
+LL+I RLR E++++ + CK C +T I ++++ +S GP+ AYVNPHGYV
Sbjct: 396 QLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYV 409
Query: 477 HEITTFNRANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWG 536
HE T +A + L GR +TE+SWFPGYAWT++ C C + +GW FTAT +++ P+ FWG
Sbjct: 456 HETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWG 409
Query: 537 IRSSQL 539
+ S L
Sbjct: 516 LTRSAL 409
BLAST of MS001195.1 vs. ExPASy Swiss-Prot
Match:
Q640S2 (Protein cereblon OS=Xenopus tropicalis OX=8364 GN=crbn PE=2 SV=1)
HSP 1 Score: 159.1 bits (401), Expect = 1.4e-37
Identity = 137/528 (25.95%), Postives = 219/528 (41.48%), Query Frame = 0
Query: 16 QILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSSLASLHTYLGEVEDAH 75
Q++ ++EE E++ +D + I F++SL + H YLG +
Sbjct: 20 QVISSESEEEDEMELEDAKTADSESPNI-----------INFDTSLPTSHAYLGVDMEEF 79
Query: 76 HRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIERVLTHFDTPNTIGVV 135
H D + +PV + +L P TLPL + + ++ + ++ T V+
Sbjct: 80 HGRTLHDDDSCQQIPVLPHVQV-MLIPGQTLPLHLSRPQEVSMVRGLI---QRDRTFAVL 139
Query: 136 HVSLDSDNEKLHFANIGTTAEIRQFRRLED---GSINVLTRGKQRFRLRRRWIDAEGVPC 195
S D + HF GTTAEI +R + ++ V G+QRF++ A+G+
Sbjct: 140 AYS-DGLQREAHF---GTTAEIYAYREEHEFGIETVKVKAIGRQRFQVLETRTQADGIQV 199
Query: 196 GEVQIIQED-LPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFTSRDEEDDSASN 255
VQI+ E LP P +S+Q S SR L T+
Sbjct: 200 ARVQILPERVLP-----------CPMTSLQLDSQSRHLLFPTN----------------- 259
Query: 256 SEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDSDSLGSMQSDYE 315
Sbjct: 260 ------------------------------------------------------------ 319
Query: 316 KENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYWVYSMYDSYCLA 375
P +G+S SK + L + RR G S WP W+Y++YD+ L
Sbjct: 320 ------KPVSGRS-----PQSKCQWLHKYRRRKFL----GASLTSWPSWLYALYDADSLM 379
Query: 376 QKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDGISYRLRREVEL 435
++ + D NP S+ +A+ +P+ ++ R +LL+I RLR E+++
Sbjct: 380 ERVKLQLHEWDENLRDDSLPANPIDFSYRVAACLPIDDALRIQLLQIGNAIQRLRCELDI 425
Query: 436 LKSIDIIQCKNC-KTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNRANGIALRGRA 495
+ + CK+C T I ++++ +S GP+ AYVNPHGYVHE T +A ++L GR
Sbjct: 440 MSKCTSLCCKHCPDTEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKAFNLSLVGRP 425
Query: 496 ATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQL 539
+TE SWFPG+AWTI+ C C + +GW FTA ++L P+ FWG+ S L
Sbjct: 500 STENSWFPGFAWTIAQCRVCGSHMGWKFTAVRKDLSPQKFWGLTRSAL 425
BLAST of MS001195.1 vs. ExPASy TrEMBL
Match:
A0A6J1BR44 (Protein cereblon OS=Momordica charantia OX=3673 GN=LOC111004827 PE=3 SV=1)
HSP 1 Score: 1049.7 bits (2713), Expect = 4.3e-303
Identity = 537/543 (98.90%), Postives = 539/543 (99.26%), Query Frame = 0
Query: 1 MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS 60
MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS
Sbjct: 1 MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS 60
Query: 61 LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIE 120
LASLHTYLGEVED+HHRMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQANFIAAIE
Sbjct: 61 LASLHTYLGEVEDSHHRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQANFIAAIE 120
Query: 121 RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL 180
RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL
Sbjct: 121 RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL 180
Query: 181 RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFT 240
RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLS ALASYTSCS QFT
Sbjct: 181 RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSCALASYTSCSRQFT 240
Query: 241 SRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS 300
SRDEE DSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS
Sbjct: 241 SRDEEVDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS 300
Query: 301 DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW 360
DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW
Sbjct: 301 DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW 360
Query: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420
VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG
Sbjct: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420
Query: 421 ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR 480
ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR
Sbjct: 421 ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR 480
Query: 481 ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540
ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD
Sbjct: 481 ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540
Query: 541 ATR 544
ATR
Sbjct: 541 ATR 542
BLAST of MS001195.1 vs. ExPASy TrEMBL
Match:
A0A6J1BQB5 (Protein cereblon OS=Momordica charantia OX=3673 GN=LOC111004827 PE=3 SV=1)
HSP 1 Score: 1045.0 bits (2701), Expect = 1.1e-301
Identity = 537/544 (98.71%), Postives = 539/544 (99.08%), Query Frame = 0
Query: 1 MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPI-HGHGGVETFAEFTFNS 60
MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPI HGHGGVETFAEFTFNS
Sbjct: 1 MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPISHGHGGVETFAEFTFNS 60
Query: 61 SLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAI 120
SLASLHTYLGEVED+HHRMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQANFIAAI
Sbjct: 61 SLASLHTYLGEVEDSHHRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQANFIAAI 120
Query: 121 ERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFR 180
ERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFR
Sbjct: 121 ERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFR 180
Query: 181 LRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQF 240
LRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLS ALASYTSCS QF
Sbjct: 181 LRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSCALASYTSCSRQF 240
Query: 241 TSRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLND 300
TSRDEE DSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLND
Sbjct: 241 TSRDEEVDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLND 300
Query: 301 SDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPY 360
SDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPY
Sbjct: 301 SDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPY 360
Query: 361 WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID 420
WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID
Sbjct: 361 WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID 420
Query: 421 GISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFN 480
GISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFN
Sbjct: 421 GISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFN 480
Query: 481 RANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA 540
RANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA
Sbjct: 481 RANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA 540
Query: 541 DATR 544
DATR
Sbjct: 541 DATR 543
BLAST of MS001195.1 vs. ExPASy TrEMBL
Match:
A0A6J1GIL0 (Protein cereblon OS=Cucurbita moschata OX=3662 GN=LOC111454509 PE=3 SV=1)
HSP 1 Score: 959.5 bits (2479), Expect = 5.9e-276
Identity = 486/543 (89.50%), Postives = 515/543 (94.84%), Query Frame = 0
Query: 1 MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS 60
MED+R+L+ ERHQIEQILQLDNEELQVEEVDYLP+SDDDRD I+ HGG E FAEFTFNSS
Sbjct: 1 MEDQRLLDNERHQIEQILQLDNEELQVEEVDYLPESDDDRDAINDHGGYEAFAEFTFNSS 60
Query: 61 LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIE 120
LASLHTYLGEVEDAHHRMAFLDGGAILN+PVFYLEG+ VLFPEATLPLRVIQ+NFIAAIE
Sbjct: 61 LASLHTYLGEVEDAHHRMAFLDGGAILNIPVFYLEGV-VLFPEATLPLRVIQSNFIAAIE 120
Query: 121 RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL 180
RVLTHFDTPNTIGVVHVS+DS +++L FANIGTTAEIRQFRRLEDGS+NVL RGKQRFRL
Sbjct: 121 RVLTHFDTPNTIGVVHVSVDSGSDRLRFANIGTTAEIRQFRRLEDGSLNVLARGKQRFRL 180
Query: 181 RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFT 240
RRRWID EGVPCGEVQIIQEDLPLRTPRDAFG+LAPR+++QRHSLS ALASYTSCS FT
Sbjct: 181 RRRWIDVEGVPCGEVQIIQEDLPLRTPRDAFGDLAPRNTIQRHSLSCALASYTSCSRPFT 240
Query: 241 SRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS 300
SRDEEDDSASNSEESFERELSLRERKIHQAAI S+ES SDEEISGSE+EHQHAMSH NDS
Sbjct: 241 SRDEEDDSASNSEESFERELSLRERKIHQAAIGSSESCSDEEISGSEAEHQHAMSHQNDS 300
Query: 301 DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW 360
DSLG + SDYEKE+EKP+PD GKSSTSA++SS+RKE + CRRNSSFN MHGVSKAF PYW
Sbjct: 301 DSLGFLHSDYEKESEKPSPDIGKSSTSAKDSSERKEFKGCRRNSSFNHMHGVSKAFLPYW 360
Query: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420
VYSMYDSYCLAQKAAAMWKQIVG PNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG
Sbjct: 361 VYSMYDSYCLAQKAAAMWKQIVGAPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420
Query: 421 ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR 480
ISYRLRRE+ELLKSID+IQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEI T R
Sbjct: 421 ISYRLRREIELLKSIDLIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEIMTLYR 480
Query: 481 ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540
ANG+ALRGRA TEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD
Sbjct: 481 ANGLALRGRAETEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540
Query: 541 ATR 544
ATR
Sbjct: 541 ATR 542
BLAST of MS001195.1 vs. ExPASy TrEMBL
Match:
A0A5A7V9Q1 (Protein cereblon OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold82G003810 PE=3 SV=1)
HSP 1 Score: 959.1 bits (2478), Expect = 7.7e-276
Identity = 492/547 (89.95%), Postives = 512/547 (93.60%), Query Frame = 0
Query: 1 MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSD----DDRDPIHGHGGVETFAEFT 60
MED+R+LERERHQIEQILQLDNEELQVEEVDYL DSD DDRD I+GHGG E FAEFT
Sbjct: 1 MEDQRLLERERHQIEQILQLDNEELQVEEVDYLHDSDDDDNDDRDAINGHGGTEAFAEFT 60
Query: 61 FNSSLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFI 120
FNSSLASLHTYLGEVEDAH RMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQ+NFI
Sbjct: 61 FNSSLASLHTYLGEVEDAHQRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQSNFI 120
Query: 121 AAIERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQ 180
AAIERVLTHFDTPNTIGVVH+SLDSD+E+L FANIGTTAEIRQFRRLEDGS+NVL RGKQ
Sbjct: 121 AAIERVLTHFDTPNTIGVVHISLDSDSERLRFANIGTTAEIRQFRRLEDGSLNVLARGKQ 180
Query: 181 RFRLRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCS 240
RFRLRRRWID EGVPCGEVQIIQEDLPLR PRDAFGELAPRS+VQRHSLS ALASYTSCS
Sbjct: 181 RFRLRRRWIDVEGVPCGEVQIIQEDLPLRAPRDAFGELAPRSTVQRHSLSCALASYTSCS 240
Query: 241 GQFTSRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSH 300
FTS+DEEDDSASNSEESFERELSLRERKIHQAAIDS ES SDEE+SGSE+EHQH+MS
Sbjct: 241 RSFTSKDEEDDSASNSEESFERELSLRERKIHQAAIDSGESCSDEEMSGSEAEHQHSMSR 300
Query: 301 LNDSDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAF 360
LNDSDSLGSM SD EKENEKPA D GKSSTSARESSK KEL+RC+RNSSFNPMH VSKAF
Sbjct: 301 LNDSDSLGSMHSDCEKENEKPASDIGKSSTSARESSKIKELKRCQRNSSFNPMHRVSKAF 360
Query: 361 WPYWVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELL 420
WPYWVYSMYDSYCLAQKAAAMWKQIVG PNMDGFVKNPDILSFYIASKIPVSESTRQELL
Sbjct: 361 WPYWVYSMYDSYCLAQKAAAMWKQIVGAPNMDGFVKNPDILSFYIASKIPVSESTRQELL 420
Query: 421 EIDGISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEIT 480
EIDGISYRLRRE+ELLKSIDIIQCKNCKTVIAK SDMLVM ++GP GAYVNPHGYVHEI
Sbjct: 421 EIDGISYRLRREIELLKSIDIIQCKNCKTVIAKHSDMLVMPNEGPFGAYVNPHGYVHEIM 480
Query: 481 TFNRANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSS 540
T RANG+ALRGRA TEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIR S
Sbjct: 481 TLYRANGLALRGRAETEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRCS 540
Query: 541 QLADATR 544
QLADATR
Sbjct: 541 QLADATR 546
BLAST of MS001195.1 vs. ExPASy TrEMBL
Match:
A0A0A0LP38 (Protein cereblon OS=Cucumis sativus OX=3659 GN=Csa_2G373420 PE=3 SV=1)
HSP 1 Score: 958.4 bits (2476), Expect = 1.3e-275
Identity = 490/547 (89.58%), Postives = 511/547 (93.42%), Query Frame = 0
Query: 1 MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSD----DDRDPIHGHGGVETFAEFT 60
MED+R+LERERHQIEQILQLDNEELQVEEVDYL DSD DDRD I+GHGG E F EFT
Sbjct: 1 MEDQRLLERERHQIEQILQLDNEELQVEEVDYLHDSDDDDNDDRDAINGHGGTEAFPEFT 60
Query: 61 FNSSLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFI 120
FNSSLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQ+NFI
Sbjct: 61 FNSSLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQSNFI 120
Query: 121 AAIERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQ 180
AAIERVLTHFDTPNTIGVVHVSLDSD+E+L FANIGTTAEIRQFRRLEDGS+NVL RGKQ
Sbjct: 121 AAIERVLTHFDTPNTIGVVHVSLDSDSERLRFANIGTTAEIRQFRRLEDGSLNVLARGKQ 180
Query: 181 RFRLRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCS 240
RFRLRRRWID EGVPCGEVQIIQEDLPLR PRDAFGELAPRS+VQRH LS ALASYT CS
Sbjct: 181 RFRLRRRWIDVEGVPCGEVQIIQEDLPLRAPRDAFGELAPRSTVQRHGLSCALASYTPCS 240
Query: 241 GQFTSRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSH 300
FTSRDEEDDSASNSEESFERELSLRE+KIH AAIDS+ES SDEE+SGSE+EHQH+MSH
Sbjct: 241 RSFTSRDEEDDSASNSEESFERELSLREKKIHNAAIDSSESCSDEEMSGSEAEHQHSMSH 300
Query: 301 LNDSDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAF 360
LNDSDSLGSM SD EKENEKPA D GKSSTSARESS+ KEL+RCRRNSSFNPMH VSKAF
Sbjct: 301 LNDSDSLGSMHSDCEKENEKPASDIGKSSTSARESSESKELKRCRRNSSFNPMHRVSKAF 360
Query: 361 WPYWVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELL 420
WPYWVYSMYDSYCLAQKAAAMWKQIVG PNMDGFVKNPDILSFYIASKIPVSESTRQELL
Sbjct: 361 WPYWVYSMYDSYCLAQKAAAMWKQIVGAPNMDGFVKNPDILSFYIASKIPVSESTRQELL 420
Query: 421 EIDGISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEIT 480
EIDGISYRLRRE+ELLKSIDIIQCKNCKTVIAK SDMLVM ++GP GAYVNPHGYVHEI
Sbjct: 421 EIDGISYRLRREIELLKSIDIIQCKNCKTVIAKHSDMLVMPNEGPFGAYVNPHGYVHEIM 480
Query: 481 TFNRANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSS 540
T RANG+ALRGRA TEYSWFPGYAWTISICATCETQLGWLFTATNRNLKP+SFWGIR S
Sbjct: 481 TLYRANGLALRGRAQTEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPKSFWGIRCS 540
Query: 541 QLADATR 544
QLADATR
Sbjct: 541 QLADATR 546
BLAST of MS001195.1 vs. TAIR 10
Match:
AT2G25740.1 (ATP-dependent protease La (LON) domain protein )
HSP 1 Score: 573.5 bits (1477), Expect = 1.7e-163
Identity = 313/557 (56.19%), Postives = 394/557 (70.74%), Query Frame = 0
Query: 1 MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRD-------PIHGH---GGVE 60
M+DER+ ERER QIEQI +LD EELQVEEVD L DSD D + P H G
Sbjct: 1 MDDERIRERERLQIEQIRELDFEELQVEEVDDLHDSDSDDNNDDLSSFPFSSHAQASGNL 60
Query: 61 TFAEFTFNSSLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRV 120
E FN +LASLH YLGEVED +R++F+DGG +L +P+FYLEG+ VLFPEATLPLR+
Sbjct: 61 GDDELMFNPALASLHMYLGEVEDTQNRVSFVDGGTVLKIPLFYLEGV-VLFPEATLPLRI 120
Query: 121 IQANFIAAIERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINV 180
IQ +F+AA+ER L + P+TIGV+ V + + +A++GTTAEIRQ+RRL DGS NV
Sbjct: 121 IQPSFLAAVERALNQANAPSTIGVIRVY--REGAQFKYASVGTTAEIRQYRRLGDGSFNV 180
Query: 181 LTRGKQRFRLRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQ-RHSLSRAL 240
+TRG+QRFRL+ RW D EG CGEVQI+ ED+PLRTPRDAFG+L P S ++ R+ L A
Sbjct: 181 ITRGQQRFRLKHRWTDVEGFTCGEVQIVDEDVPLRTPRDAFGKLVPLSKLRGRYPLGTAS 240
Query: 241 ASYTSCSGQFTSRDEEDDSASNSEESFERELSLRERKIHQAAIDS---NESSSDEEISGS 300
S RD + S +NSEESFE LS E+++H + +DS N +SSD++ S
Sbjct: 241 LS-------TPLRDMDAQSEANSEESFESALSPSEKRLHYSVVDSIFCNSTSSDDDQVVS 300
Query: 301 ESEHQHAMSHLNDSDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSF 360
S Q + S+ S+G + S ++ ENE GK+ S + K+ L R+N+
Sbjct: 301 TSTVQSSGSNPYSLRSIGCLASSHDNENEDEQSAIGKTPVSQEKYQKQNRLASFRQNTDL 360
Query: 361 NPMHGVSKAFWPYWVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIP 420
+ +AFWP+W Y M+DSY LAQ+A +WKQIVGVPNM+ FV PDILSF IASKIP
Sbjct: 361 SRFRMTPRAFWPFWAYRMFDSYYLAQRAVDLWKQIVGVPNMEAFVNKPDILSFSIASKIP 420
Query: 421 VSESTRQELLEIDGISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYV 480
VSES RQELLE+DG+SYRL+RE+ELL+S D ++C +C+TVIA+R DMLVMS++GPLGAYV
Sbjct: 421 VSESIRQELLELDGVSYRLQREIELLESFDRVRCIHCQTVIARRKDMLVMSNEGPLGAYV 480
Query: 481 NPHGYVHEITTFNRANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLK 540
NPHGYVHEI TF +AN IALRGR + SWFPGYAWTI+ CATCETQLGW FTATN+ LK
Sbjct: 481 NPHGYVHEIMTFYKANDIALRGRPVKKDSWFPGYAWTIANCATCETQLGWHFTATNKKLK 540
Query: 541 PRSFWGIRSSQLADATR 544
P SFW +R SQ+AD R
Sbjct: 541 PSSFWAVRGSQVADDMR 547
The following BLAST results are available for this feature:
Match Name | E-value | Identity | Description | |
XP_022131733.1 | 8.9e-303 | 98.90 | protein cereblon isoform X3 [Momordica charantia] >XP_022131734.1 protein cerebl... | [more] |
XP_022131731.1 | 2.2e-301 | 98.71 | protein cereblon isoform X1 [Momordica charantia] >XP_022131732.1 protein cerebl... | [more] |
XP_038885492.1 | 4.4e-278 | 91.16 | protein cereblon isoform X2 [Benincasa hispida] | [more] |
XP_038885491.1 | 1.1e-276 | 90.99 | protein cereblon isoform X1 [Benincasa hispida] | [more] |
KAG6585376.1 | 1.2e-275 | 89.50 | Protein cereblon, partial [Cucurbita argyrosperma subsp. sororia] | [more] |
Match Name | E-value | Identity | Description | |
Q68EH9 | 7.4e-42 | 27.05 | Protein cereblon OS=Danio rerio OX=7955 GN=crbn PE=1 SV=1 | [more] |
Q0P564 | 4.5e-39 | 25.81 | Protein cereblon OS=Bos taurus OX=9913 GN=CRBN PE=2 SV=1 | [more] |
Q96SW2 | 5.8e-39 | 26.02 | Protein cereblon OS=Homo sapiens OX=9606 GN=CRBN PE=1 SV=1 | [more] |
Q5R6Y2 | 1.3e-38 | 25.93 | Protein cereblon OS=Pongo abelii OX=9601 GN=CRBN PE=2 SV=1 | [more] |
Q640S2 | 1.4e-37 | 25.95 | Protein cereblon OS=Xenopus tropicalis OX=8364 GN=crbn PE=2 SV=1 | [more] |
Match Name | E-value | Identity | Description | |
A0A6J1BR44 | 4.3e-303 | 98.90 | Protein cereblon OS=Momordica charantia OX=3673 GN=LOC111004827 PE=3 SV=1 | [more] |
A0A6J1BQB5 | 1.1e-301 | 98.71 | Protein cereblon OS=Momordica charantia OX=3673 GN=LOC111004827 PE=3 SV=1 | [more] |
A0A6J1GIL0 | 5.9e-276 | 89.50 | Protein cereblon OS=Cucurbita moschata OX=3662 GN=LOC111454509 PE=3 SV=1 | [more] |
A0A5A7V9Q1 | 7.7e-276 | 89.95 | Protein cereblon OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold82G0038... | [more] |
A0A0A0LP38 | 1.3e-275 | 89.58 | Protein cereblon OS=Cucumis sativus OX=3659 GN=Csa_2G373420 PE=3 SV=1 | [more] |
Match Name | E-value | Identity | Description | |
AT2G25740.1 | 1.7e-163 | 56.19 | ATP-dependent protease La (LON) domain protein | [more] |