MS001195 (gene) Bitter gourd (TR) v1

Overview


Name	MS001195
Type	gene
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	Protein cereblon
Location	scaffold36: 2198572 .. 2203378 (+)
RNA-Seq Expression	MS001195
Synteny	MS001195

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: CDSpolypeptide

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGGAGGACGAGAGGGTTTTGGAGAGGGAGAGGCACCAGATCGAGCAGATTCTTCAGCTTGATAATGAGGAGTTGCAAGTTGAGGAAGTTGACTATCTCCCCGACTCCGACGATGATCGCGACCCTATGTAATGTTTACTCCCTCCGGTTTTAGGGTTTTCACATTTCATTTTCGCGTAGGGTTTTTGCAGTACTCTGAATTGGATTCATCTGAATTACTGATAGTGACATGATAGTGCTTAAATCGCTGAATTAGAATTTGAAGAATGGTTGCTCTGTTGGGAACTTCTTTAAAGATTGGATTAATTCTGGGATTTAACTTTTAAGTTAAGATGCTAGCTTCGGTGCACTACATGGCGCACCTTTTAGTTGACTCGAACAATTTCTCCATTTCTCATATTATGTCGAAATGGATTTGGTTTTTGCATGTTTTGGCATTAGTACTACATGCAGAGAAGTTGTTGGAGTGAATCGTCGGATACACTAATGGCTTAATGACCAAGTCACTTGGCAAATGGCTCACGATAGTCAGTGGTTCATGCTATCTTTACTTTCTCTTGTTTGTTCCAATTGCCGAAACTCTTGAAAATCTGGAATTGGAGTAGAGATTTGAGACCAGTCCACTTTCTACTCTTTGTGAAGATACCACGCAAACTTAGAATGGGCACTTGAGTATCGATTAGTTTCTGTCATTAAGTCCTTGTACACGGCCTAGCACGATTATTAGATTTTATATATCCTTTTCTCCATCTGAAATGACTAGTCACTGAATTTGTTTGCTATACTAGTCACTCGTGTTAGCAAAAAGGTGACTTTATTAATGAATTGAATTGCTTTATTGATTTTGTTTGCTATACTAGTCCTCTAGCTGCTGCTGTCGTTCTTATTGTTATTACTATTTTGTGAGTGGGACTGTGGGGGATATTTTGGTTTTCATCCAAGGCACTGACACCCTCCTGTTTTTCCCTATTGTATCAAAGCAGCCATGGTCATGGAGGTGTTGAGACCTTTGCTGAATTTACTTTCAATTCCTCTTTGGCTTCTTTGCATACGTATCTTGGTGGTATGGAATTGCTATTCTGTTTTTATTTGCTGATTAATATTTCGAGAATTCATGCCAATTCCATTTGGGGTACTGTCTTACTAATATCTCCTGTGGCTACGTGTAACAGAGGTTGAGGATGCTCATCACAGAATGGCTTTCTTGGATGGTGGTGCCATACTGAACCTTCCTGTATTTTATCTTGAAGGTATTTGTTTATTAATTCTTCTTCGTTCTGCTTCTAGCATCGAATTGCATGGGTTTAAGTGCCATAACTGGAGTAGGATAGTTACAAACTATCCCTATTTAATTTTTGATATCTACTAATCAGATTTTTGTATTTTAGAAATGGCATTGAAAAACATCCTTAGTCTGAAGAATCAAAATCTGCAAATCATGCAATTCTGTTCAAGTCAATTGTTATTGTCAATGTTGTTGTCTCAGACAATTTGTTATTTCAATGGAATTGACACATAAAATTCACTCAATATGTGGACCATGATTAAAATCTCGTTCTGTTAAAAGTGATGATGATTTAATAGAAAGTTATGTATGTTTGTAGATTTTGCAAATGACGAAGGTGTTTAAAACTAGTTTAAGATTTCAATGCTCATTACATAGGATTAGAAAACTGCAATTATCGAATAGGTATCCTTTTGCTTGGAGAGAGCTGTTATAGTTTATCATGTCTAGTTAATGTCTGAAGCAGCAAGCTCTTTACCCCCACCCATGGGGAGTGAGGAAATAACATGTTTGTTAATCGCCATCCTCTTGCTTGATGCGGTTAGATGACCTGCAGGCCCACACATCAGACATAATTGCCAGTTGCCACCGGATGAAGAATAGTTCAATCTAGTAGCCCTTGATTTTTCCAACTTTAAGTGGACAAGTAAATTTTTTTATGATTACACTGGTCAACAGGCATATAGTAACCTTCTTCGGGATACCTTTTTCCATTTTGTCACTACTATTATTACGTCATGTACAATCACATATTTCTCAGGAGTTGTGTTGTTCCCGGAAGCTACTCTGCCTCTCAGGGTGATCCAAGCAAATTTTATTGCTGCCATTGAAAGAGTACTGACTCATTTTGACACCCCTAATACCATAGGTGTGGTATGTGCTCTAATTTAGGCATCATGCGCATAATTTTAAAGATTCCATTGAAATCCCTTATTGGTAGCTCAAACAAGATTTAATATTCTATTCAGGTTCACGTCTCCTTGGATTCTGACAACGAGAAACTACATTTTGCAAATATTGGGACGACTGCAGAGGTAGTATTTTTTCGATTTTGATTCTCTTGGCCTTTTCCTCTTCTGGCATTATCCGAAAAGCAATTAGTTTTTGGAGTTCGGCCTCTTGCCATGATTTGGGGTTGTTTAGCTTCCATCCGAATTTTAATGTAAGGATGCTACCATGTTTCTAATGACATTCATCCATGTTCCTACCAACTCTCTCTATTATAGATACGGCAGTTTCGAAGGTTGGAGGATGGTTCAATCAATGTTCTTACTAGAGGGAAGCAAAGATTTCGCCTTAGACGCCGTTGGATCGATGCTGAAGGAGTGGTTAGAGCAAATTTTTGTTCTTGAATTATTTGCGTTATTTACTTATTATTTTAGTGTTTTTATGATGCAAGTATAATTTGGTATAAAAATGCAATCTTTTTAGCCATGTGGAGAAGTTCAAATTATCCAGGAAGATTTGCCATTAAGGACTCCACGGGATGCTTTCGGAGAATTGGCTCCAAGGAGCAGTGTCCAGCGCCACAGTCTCTCACGTGCATTGGCTTCATATACTTCTTGCTCTGGACAATTTACGTCAAGGGATGAGGAGGATGATTCAGCCTCTAATTCAGAAGAAAGCTTTGAACGTGAGCTTTCATTGAGAGAGAGGAAAATCCACCAAGCAGCAATCGATTCCAATGAGTCTAGTAGTGATGAGGAGATATCTGGCTCAGAGTCTGAACACCAACATGCAATGTCACATCTAAATGACTCGGATTCTTTAGGGTCAATGCAGTCTGACTATGAGAAGGAAAATGAAAAACCTGCCCCTGATACAGGAAAGAGTTCCACATCAGCTAGGGAATCTAGCAAAAGGAAAGAACTTGAAAGATGTCGAAGAAACTCAAGTTTTAATCCGATGCATGGGGTTTCAAAAGCATTTTGGCCATATTGGGTTTACTCTATGTATGACTCCTATTGTCTTGCTCAAAAAGCAGCAGGTGATCTGAGTTGTTCTCCTTCACTCTCAGCCTTTCATTTCTTTCCTTTTCATTTTTTGTTTCTGTTTTCAATGTAGATATGTGCATTTCACTCGTTTCTTATCATTTGGTGGCGAAAGTGTTTTGATTCTGTACTTTTCAGTGTGATTTATTGATTGAAAAATAAAAACCCCTGTTTGCTGTTTGCCATATCTCGGGACATAACATTCTGTCTGCAATATATCTAGAAAATTGGAGGCACATGTATTGGTCTCTTTTTTATTCCTTACCATCACTATTTTCAGCTATGTGGAAGCAGATTGTGGGGGTTCCAAACATGGATGGTTTTGTGAAGAATCCAGACATTTTATCATTCTACATTGCTAGTAAGATTCCAGTTTCTGAATCTACTAGACAGGAGCTCTTGGAGATTGATGGCATTTCATATAGATTGCGCCGGGAAGTCGAGTTACTTAAGTCTATTGATATCATCCAATGTAAAAACTGTAAGGTAGTCAATAGTCTCTGAGTATGTATGCTTGCACTCTATCAATTTGACATCTTGCATGCGCCCTCAGCTTATGCTTAATTGCGCTGTGTAGTTATTCCATGGCATACTTAGCTGCCTATTGTTTTTATATGTCATTTCCTCTTATGCAGACAGTTATAGCCAAACGCAGTGATATGTTGGTGATGTCTAGTGATGGTCCACTCGGTGCTTATGTGAACCCCCATGGTTATGTGCATGAAATAACGACTTTTAACAGAGCAAATGGCATAGCACTAAGAGGACGAGCCGCTACAGAATACAGTTGGTTCCCTGGGTATGCTATTGACCTAACTTTTCTTTCCTTTGAACCTATGAGTAGCCTTTTACTCCCTTTGTTGTTTGATTGTACAAAAAACTTGTTTGTTGTTTGATTGTAGAAAAGTTATTGTGCTGATTTTGTTTCTAGCACTAAATTAAACTTCAAGCATGAAGTACACTCGATCATGGTTCCCCTTTAATTTTTACATTAGTAGGAAAATGGTTTCTAGGTTAACGTGAAGAGTTATCAGCTGTCAACTCATAATTCTGTGGTTTAAGATGTTCTCTTGGGACTTGGACCTAAGACTTCAGTTGGTAACTGGAACCTTTGACCCCAAATAGGTTATTGCTTGATAATTATGAATAGGCAGATGGAGCATGATTTCATACCTAGACGTAGGATTAAGGTAGCATTTCTAGTGGGAATCCATATATGAATTTGAGAATTAGAAACTAGTGCAAATATTGACTAGTTATGAGAAAAGACAACTTCTGATATTTATGGATATTCAGAACATTGGGTAGTTAGAGATGAAACTAATTATTTTATGTTTTTTTTTAATCTCTCATCCATTTTATACTGTAAATGCGAGACTCTGACTTCCGCTGTTTTAGGTATGCATGGACAATCTCAATCTGTGCCACTTGTGAAACTCAATTAGGATGGCTTTTTACTGCCACAAACAGGAATCTGAAACCTAGATCTTTTTGGGGAATACGTAGTTCCCAGTTAGCTGATGCCACACGG

mRNA sequence

ATGGAGGACGAGAGGGTTTTGGAGAGGGAGAGGCACCAGATCGAGCAGATTCTTCAGCTTGATAATGAGGAGTTGCAAGTTGAGGAAGTTGACTATCTCCCCGACTCCGACGATGATCGCGACCCTATCCATGGTCATGGAGGTGTTGAGACCTTTGCTGAATTTACTTTCAATTCCTCTTTGGCTTCTTTGCATACGTATCTTGGTGAGGTTGAGGATGCTCATCACAGAATGGCTTTCTTGGATGGTGGTGCCATACTGAACCTTCCTGTATTTTATCTTGAAGGTATTTTTGTGTTGTTCCCGGAAGCTACTCTGCCTCTCAGGGTGATCCAAGCAAATTTTATTGCTGCCATTGAAAGAGTACTGACTCATTTTGACACCCCTAATACCATAGGTGTGGTTCACGTCTCCTTGGATTCTGACAACGAGAAACTACATTTTGCAAATATTGGGACGACTGCAGAGATACGGCAGTTTCGAAGGTTGGAGGATGGTTCAATCAATGTTCTTACTAGAGGGAAGCAAAGATTTCGCCTTAGACGCCGTTGGATCGATGCTGAAGGAGTGCCATGTGGAGAAGTTCAAATTATCCAGGAAGATTTGCCATTAAGGACTCCACGGGATGCTTTCGGAGAATTGGCTCCAAGGAGCAGTGTCCAGCGCCACAGTCTCTCACGTGCATTGGCTTCATATACTTCTTGCTCTGGACAATTTACGTCAAGGGATGAGGAGGATGATTCAGCCTCTAATTCAGAAGAAAGCTTTGAACGTGAGCTTTCATTGAGAGAGAGGAAAATCCACCAAGCAGCAATCGATTCCAATGAGTCTAGTAGTGATGAGGAGATATCTGGCTCAGAGTCTGAACACCAACATGCAATGTCACATCTAAATGACTCGGATTCTTTAGGGTCAATGCAGTCTGACTATGAGAAGGAAAATGAAAAACCTGCCCCTGATACAGGAAAGAGTTCCACATCAGCTAGGGAATCTAGCAAAAGGAAAGAACTTGAAAGATGTCGAAGAAACTCAAGTTTTAATCCGATGCATGGGGTTTCAAAAGCATTTTGGCCATATTGGGTTTACTCTATGTATGACTCCTATTGTCTTGCTCAAAAAGCAGCAGCTATGTGGAAGCAGATTGTGGGGGTTCCAAACATGGATGGTTTTGTGAAGAATCCAGACATTTTATCATTCTACATTGCTAGTAAGATTCCAGTTTCTGAATCTACTAGACAGGAGCTCTTGGAGATTGATGGCATTTCATATAGATTGCGCCGGGAAGTCGAGTTACTTAAGTCTATTGATATCATCCAATGTAAAAACTGTAAGACAGTTATAGCCAAACGCAGTGATATGTTGGTGATGTCTAGTGATGGTCCACTCGGTGCTTATGTGAACCCCCATGGTTATGTGCATGAAATAACGACTTTTAACAGAGCAAATGGCATAGCACTAAGAGGACGAGCCGCTACAGAATACAGTTGGTTCCCTGGGTATGCATGGACAATCTCAATCTGTGCCACTTGTGAAACTCAATTAGGATGGCTTTTTACTGCCACAAACAGGAATCTGAAACCTAGATCTTTTTGGGGAATACGTAGTTCCCAGTTAGCTGATGCCACACGG

Coding sequence (CDS)

ATGGAGGACGAGAGGGTTTTGGAGAGGGAGAGGCACCAGATCGAGCAGATTCTTCAGCTTGATAATGAGGAGTTGCAAGTTGAGGAAGTTGACTATCTCCCCGACTCCGACGATGATCGCGACCCTATCCATGGTCATGGAGGTGTTGAGACCTTTGCTGAATTTACTTTCAATTCCTCTTTGGCTTCTTTGCATACGTATCTTGGTGAGGTTGAGGATGCTCATCACAGAATGGCTTTCTTGGATGGTGGTGCCATACTGAACCTTCCTGTATTTTATCTTGAAGGTATTTTTGTGTTGTTCCCGGAAGCTACTCTGCCTCTCAGGGTGATCCAAGCAAATTTTATTGCTGCCATTGAAAGAGTACTGACTCATTTTGACACCCCTAATACCATAGGTGTGGTTCACGTCTCCTTGGATTCTGACAACGAGAAACTACATTTTGCAAATATTGGGACGACTGCAGAGATACGGCAGTTTCGAAGGTTGGAGGATGGTTCAATCAATGTTCTTACTAGAGGGAAGCAAAGATTTCGCCTTAGACGCCGTTGGATCGATGCTGAAGGAGTGCCATGTGGAGAAGTTCAAATTATCCAGGAAGATTTGCCATTAAGGACTCCACGGGATGCTTTCGGAGAATTGGCTCCAAGGAGCAGTGTCCAGCGCCACAGTCTCTCACGTGCATTGGCTTCATATACTTCTTGCTCTGGACAATTTACGTCAAGGGATGAGGAGGATGATTCAGCCTCTAATTCAGAAGAAAGCTTTGAACGTGAGCTTTCATTGAGAGAGAGGAAAATCCACCAAGCAGCAATCGATTCCAATGAGTCTAGTAGTGATGAGGAGATATCTGGCTCAGAGTCTGAACACCAACATGCAATGTCACATCTAAATGACTCGGATTCTTTAGGGTCAATGCAGTCTGACTATGAGAAGGAAAATGAAAAACCTGCCCCTGATACAGGAAAGAGTTCCACATCAGCTAGGGAATCTAGCAAAAGGAAAGAACTTGAAAGATGTCGAAGAAACTCAAGTTTTAATCCGATGCATGGGGTTTCAAAAGCATTTTGGCCATATTGGGTTTACTCTATGTATGACTCCTATTGTCTTGCTCAAAAAGCAGCAGCTATGTGGAAGCAGATTGTGGGGGTTCCAAACATGGATGGTTTTGTGAAGAATCCAGACATTTTATCATTCTACATTGCTAGTAAGATTCCAGTTTCTGAATCTACTAGACAGGAGCTCTTGGAGATTGATGGCATTTCATATAGATTGCGCCGGGAAGTCGAGTTACTTAAGTCTATTGATATCATCCAATGTAAAAACTGTAAGACAGTTATAGCCAAACGCAGTGATATGTTGGTGATGTCTAGTGATGGTCCACTCGGTGCTTATGTGAACCCCCATGGTTATGTGCATGAAATAACGACTTTTAACAGAGCAAATGGCATAGCACTAAGAGGACGAGCCGCTACAGAATACAGTTGGTTCCCTGGGTATGCATGGACAATCTCAATCTGTGCCACTTGTGAAACTCAATTAGGATGGCTTTTTACTGCCACAAACAGGAATCTGAAACCTAGATCTTTTTGGGGAATACGTAGTTCCCAGTTAGCTGATGCCACACGG

Protein sequence

MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSSLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRLRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFTSRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDSDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYWVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDGISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNRANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLADATR

Homology

[Close]

BLAST of MS001195 vs. NCBI nr
Match: XP_022131733.1 (protein cereblon isoform X3 [Momordica charantia] >XP_022131734.1 protein cereblon isoform X4 [Momordica charantia])

HSP 1 Score: 1049.7 bits (2713), Expect = 8.9e-303
Identity = 537/543 (98.90%), Postives = 539/543 (99.26%), Query Frame = 0


Query: 1   MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS 60
           MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS
Sbjct: 1   MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS 60

Query: 61  LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIE 120
           LASLHTYLGEVED+HHRMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQANFIAAIE
Sbjct: 61  LASLHTYLGEVEDSHHRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQANFIAAIE 120

Query: 121 RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL 180
           RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL
Sbjct: 121 RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL 180

Query: 181 RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFT 240
           RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLS ALASYTSCS QFT
Sbjct: 181 RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSCALASYTSCSRQFT 240

Query: 241 SRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS 300
           SRDEE DSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS
Sbjct: 241 SRDEEVDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS 300

Query: 301 DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW 360
           DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW
Sbjct: 301 DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW 360

Query: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420
           VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG
Sbjct: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420

Query: 421 ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR 480
           ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR
Sbjct: 421 ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR 480

Query: 481 ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540
           ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD
Sbjct: 481 ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540

Query: 541 ATR 544
           ATR
Sbjct: 541 ATR 542

[Close]

BLAST of MS001195 vs. NCBI nr
Match: XP_022131731.1 (protein cereblon isoform X1 [Momordica charantia] >XP_022131732.1 protein cereblon isoform X2 [Momordica charantia])

HSP 1 Score: 1045.0 bits (2701), Expect = 2.2e-301
Identity = 537/544 (98.71%), Postives = 539/544 (99.08%), Query Frame = 0


Query: 1   MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPI-HGHGGVETFAEFTFNS 60
           MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPI HGHGGVETFAEFTFNS
Sbjct: 1   MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPISHGHGGVETFAEFTFNS 60

Query: 61  SLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAI 120
           SLASLHTYLGEVED+HHRMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQANFIAAI
Sbjct: 61  SLASLHTYLGEVEDSHHRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQANFIAAI 120

Query: 121 ERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFR 180
           ERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFR
Sbjct: 121 ERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFR 180

Query: 181 LRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQF 240
           LRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLS ALASYTSCS QF
Sbjct: 181 LRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSCALASYTSCSRQF 240

Query: 241 TSRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLND 300
           TSRDEE DSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLND
Sbjct: 241 TSRDEEVDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLND 300

Query: 301 SDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPY 360
           SDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPY
Sbjct: 301 SDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPY 360

Query: 361 WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID 420
           WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID
Sbjct: 361 WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID 420

Query: 421 GISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFN 480
           GISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFN
Sbjct: 421 GISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFN 480

Query: 481 RANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA 540
           RANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA
Sbjct: 481 RANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA 540

Query: 541 DATR 544
           DATR
Sbjct: 541 DATR 543

[Close]

BLAST of MS001195 vs. NCBI nr
Match: XP_038885492.1 (protein cereblon isoform X2 [Benincasa hispida])

HSP 1 Score: 967.6 bits (2500), Expect = 4.4e-278
Identity = 495/543 (91.16%), Postives = 516/543 (95.03%), Query Frame = 0


Query: 1   MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS 60
           MED+R+LERERHQIEQILQLDNEELQVEEVDYL DSDDD D I+GHGG E FAEFTFNS 
Sbjct: 1   MEDQRLLERERHQIEQILQLDNEELQVEEVDYLHDSDDDGDAINGHGGTEAFAEFTFNSY 60

Query: 61  LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIE 120
           LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQ+NFIAAIE
Sbjct: 61  LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQSNFIAAIE 120

Query: 121 RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL 180
           RVLTHFDTPNTIGVVHVS+DSDNE+L FAN+GTTAEIRQFRRLEDGS+NVL RGKQRFRL
Sbjct: 121 RVLTHFDTPNTIGVVHVSVDSDNERLRFANVGTTAEIRQFRRLEDGSLNVLARGKQRFRL 180

Query: 181 RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFT 240
           RRRWID EGVPCGEVQIIQEDLPLRTPRDAFG+LAPRS+VQRHSLS ALASYTSCS  FT
Sbjct: 181 RRRWIDVEGVPCGEVQIIQEDLPLRTPRDAFGDLAPRSTVQRHSLSCALASYTSCSRSFT 240

Query: 241 SRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS 300
           SRD EDDSASNSEESFERELSLRERKIHQAAIDS+ES SDEEISGSE+EHQHAMSHLNDS
Sbjct: 241 SRD-EDDSASNSEESFERELSLRERKIHQAAIDSSESCSDEEISGSEAEHQHAMSHLNDS 300

Query: 301 DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW 360
           DS+GSM SD EKENEKPA D GKSSTSARESS+RKEL+RC+RNSSFN MH  SKAFWPYW
Sbjct: 301 DSVGSMHSDCEKENEKPASDIGKSSTSARESSERKELKRCQRNSSFNLMHRASKAFWPYW 360

Query: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420
           VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG
Sbjct: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420

Query: 421 ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR 480
           ISYRLRRE+ELLKSIDIIQCKNCKTVIAKRSDMLVMS++GPLGAYVNPHGYVHEI T  R
Sbjct: 421 ISYRLRREIELLKSIDIIQCKNCKTVIAKRSDMLVMSTEGPLGAYVNPHGYVHEIMTLYR 480

Query: 481 ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540
           ANG+ALRGRA TEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD
Sbjct: 481 ANGLALRGRAETEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540

Query: 541 ATR 544
            TR
Sbjct: 541 VTR 541

[Close]

BLAST of MS001195 vs. NCBI nr
Match: XP_038885491.1 (protein cereblon isoform X1 [Benincasa hispida])

HSP 1 Score: 963.0 bits (2488), Expect = 1.1e-276
Identity = 495/544 (90.99%), Postives = 516/544 (94.85%), Query Frame = 0


Query: 1   MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPI-HGHGGVETFAEFTFNS 60
           MED+R+LERERHQIEQILQLDNEELQVEEVDYL DSDDD D I +GHGG E FAEFTFNS
Sbjct: 1   MEDQRLLERERHQIEQILQLDNEELQVEEVDYLHDSDDDGDAISNGHGGTEAFAEFTFNS 60

Query: 61  SLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAI 120
            LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQ+NFIAAI
Sbjct: 61  YLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQSNFIAAI 120

Query: 121 ERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFR 180
           ERVLTHFDTPNTIGVVHVS+DSDNE+L FAN+GTTAEIRQFRRLEDGS+NVL RGKQRFR
Sbjct: 121 ERVLTHFDTPNTIGVVHVSVDSDNERLRFANVGTTAEIRQFRRLEDGSLNVLARGKQRFR 180

Query: 181 LRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQF 240
           LRRRWID EGVPCGEVQIIQEDLPLRTPRDAFG+LAPRS+VQRHSLS ALASYTSCS  F
Sbjct: 181 LRRRWIDVEGVPCGEVQIIQEDLPLRTPRDAFGDLAPRSTVQRHSLSCALASYTSCSRSF 240

Query: 241 TSRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLND 300
           TSRD EDDSASNSEESFERELSLRERKIHQAAIDS+ES SDEEISGSE+EHQHAMSHLND
Sbjct: 241 TSRD-EDDSASNSEESFERELSLRERKIHQAAIDSSESCSDEEISGSEAEHQHAMSHLND 300

Query: 301 SDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPY 360
           SDS+GSM SD EKENEKPA D GKSSTSARESS+RKEL+RC+RNSSFN MH  SKAFWPY
Sbjct: 301 SDSVGSMHSDCEKENEKPASDIGKSSTSARESSERKELKRCQRNSSFNLMHRASKAFWPY 360

Query: 361 WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID 420
           WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID
Sbjct: 361 WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID 420

Query: 421 GISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFN 480
           GISYRLRRE+ELLKSIDIIQCKNCKTVIAKRSDMLVMS++GPLGAYVNPHGYVHEI T  
Sbjct: 421 GISYRLRREIELLKSIDIIQCKNCKTVIAKRSDMLVMSTEGPLGAYVNPHGYVHEIMTLY 480

Query: 481 RANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA 540
           RANG+ALRGRA TEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA
Sbjct: 481 RANGLALRGRAETEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA 540

Query: 541 DATR 544
           D TR
Sbjct: 541 DVTR 542

[Close]

BLAST of MS001195 vs. NCBI nr
Match: KAG6585376.1 (Protein cereblon, partial [Cucurbita argyrosperma subsp. sororia])

HSP 1 Score: 959.5 bits (2479), Expect = 1.2e-275
Identity = 486/543 (89.50%), Postives = 515/543 (94.84%), Query Frame = 0


Query: 1   MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS 60
           MED+R+L+ ERHQIEQILQLDNEELQVEEVDYLP+SDDDRD I+ HGG E FAEFTFNSS
Sbjct: 1   MEDQRLLDNERHQIEQILQLDNEELQVEEVDYLPESDDDRDAINDHGGYEAFAEFTFNSS 60

Query: 61  LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIE 120
           LASLHTYLGEVEDAHHRMAFLDGGAILN+PVFYLEG+ VLFPEATLPLRVIQ+NFIAAIE
Sbjct: 61  LASLHTYLGEVEDAHHRMAFLDGGAILNIPVFYLEGV-VLFPEATLPLRVIQSNFIAAIE 120

Query: 121 RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL 180
           RVLTHFDTPNTIGVVHVS+DS +++L FANIGTTAEIRQFRRLEDGS+NVL RGKQRFRL
Sbjct: 121 RVLTHFDTPNTIGVVHVSVDSGSDRLRFANIGTTAEIRQFRRLEDGSLNVLARGKQRFRL 180

Query: 181 RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFT 240
           RRRWID EGVPCGEVQIIQEDLPLRTPRDAFG+LAPR+++QRHSLS ALASYTSCS  FT
Sbjct: 181 RRRWIDVEGVPCGEVQIIQEDLPLRTPRDAFGDLAPRNTIQRHSLSCALASYTSCSRPFT 240

Query: 241 SRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS 300
           SRDEEDDSASNSEESFERELSLRERKIHQAAI S+ES SDEEISGSE+EHQHAMSH NDS
Sbjct: 241 SRDEEDDSASNSEESFERELSLRERKIHQAAIGSSESCSDEEISGSEAEHQHAMSHQNDS 300

Query: 301 DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW 360
           DSLG + SDYEKE+EKP+PD GKSSTSA++SS+RKE + CRRNSSFN MHGVSKAF PYW
Sbjct: 301 DSLGFLHSDYEKESEKPSPDIGKSSTSAKDSSERKEFKGCRRNSSFNHMHGVSKAFLPYW 360

Query: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420
           VYSMYDSYCLAQKAAAMWKQIVG PNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG
Sbjct: 361 VYSMYDSYCLAQKAAAMWKQIVGAPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420

Query: 421 ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR 480
           ISYRLRRE+ELLKSID+IQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEI T  R
Sbjct: 421 ISYRLRREIELLKSIDLIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEIMTLYR 480

Query: 481 ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540
           ANG+ALRGRA TEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD
Sbjct: 481 ANGLALRGRAETEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540

Query: 541 ATR 544
           ATR
Sbjct: 541 ATR 542

[Close]

BLAST of MS001195 vs. ExPASy Swiss-Prot
Match: Q68EH9 (Protein cereblon OS=Danio rerio OX=7955 GN=crbn PE=1 SV=1)

HSP 1 Score: 173.3 bits (438), Expect = 7.4e-42
Identity = 142/525 (27.05%), Postives = 220/525 (41.90%), Query Frame = 0


Query: 18  LQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSSLASLHTYLGEVEDAHHR 77
           LQL  E  + EE D   +  D  D       VE  +   F++SL + H YLG   +  H 
Sbjct: 5   LQLLPENEEEEEDDMETEDRDGED-------VEKPSIINFDTSLPTSHAYLGSDMEEFHG 64

Query: 78  MAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIERVLTHFDTPNTIGVVHV 137
               D  ++ NLPV     + +L P  TLPL++ +   ++    +++      T  V+  
Sbjct: 65  RTLHDEDSVQNLPVLPHVAL-ILIPGQTLPLQLFRPQEVSMFRNLVSQ---DRTFAVLAH 124

Query: 138 SLDSDNEKLHFANIGTTAEIRQFRRLED---GSINVLTRGKQRFRLRRRWIDAEGVPCGE 197
           S D    +   A  GTTAEI  FR  ++    ++ +   G+QRFR+      A+G+   +
Sbjct: 125 SPDPSGTETK-AEFGTTAEIYAFREEQEYGIETVKIKAVGRQRFRVHDIRTQADGIRQAK 184

Query: 198 VQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFTSRDEEDDSASNSEE 257
           VQI+ E + L  P                           C+ QF  R            
Sbjct: 185 VQILPERI-LPDP--------------------------LCALQFLPR------------ 244

Query: 258 SFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDSDSLGSMQSDYEKEN 317
                                              H H                      
Sbjct: 245 ----------------------------------LHTH---------------------- 304

Query: 318 EKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYWVYSMYDSYCLAQKA 377
              +P T  + T+  +       +RC +N     +H  S   WP WVYS+YDS  L  + 
Sbjct: 305 ---SPQTKHTQTTPPQ-------KRCSQNYRQKKLHCASMTSWPPWVYSLYDSKTLMSRV 364

Query: 378 AAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDGISYRLRREVELLKS 437
                +       +    NP   S+ +A+ +P+ ++ R +LL+I     RLR E++++  
Sbjct: 365 KKQLHEWDENLKDESLPTNPTDFSYRVAACLPIDDALRLQLLKIGSAIQRLRCELDIMDR 412

Query: 438 IDIIQCKNCK-TVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNRANGIALRGRAATE 497
              + CK C+ T I  ++++  +S  GP+ AYVNPHGYVHE  T  +A+ + L GR +T 
Sbjct: 425 CTSLCCKQCQDTEITSKNEIFSLSLYGPMAAYVNPHGYVHETLTVYKASNLNLIGRPSTL 412

Query: 498 YSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQL 539
           +SWFPGYAWTI+ C TC + +GW F+A  ++L P  FWG+  S L
Sbjct: 485 HSWFPGYAWTIAQCRTCSSHMGWKFSAVKKDLSPPRFWGLTRSAL 412

[Close]

BLAST of MS001195 vs. ExPASy Swiss-Prot
Match: Q0P564 (Protein cereblon OS=Bos taurus OX=9913 GN=CRBN PE=2 SV=1)

HSP 1 Score: 164.1 bits (414), Expect = 4.5e-39
Identity = 135/523 (25.81%), Postives = 223/523 (42.64%), Query Frame = 0


Query: 20  LDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSSLASLHTYLGEVEDAHHRMA 79
           L  EE + +E++   +  D+++P   +          F++SL + HTYLG   +  H   
Sbjct: 21  LPAEEEEEDEIEMEVEDQDNKEPKKPN-------IINFDTSLPTSHTYLGSDMEEFHGRT 80

Query: 80  FLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIERVLTHFDTPNTIGVVHVSL 139
             D  +   +PV   + +  L P  TLPL++     ++ +  ++       T  V+  S 
Sbjct: 81  LHDDDSCPVIPVL-PQVVMTLIPGQTLPLQLFSPQEVSMVRNLI---QKDRTFAVLAYSN 140

Query: 140 DSDNEKLHFANIGTTAEIRQFRRLEDGSINVL---TRGKQRFRLRRRWIDAEGVPCGEVQ 199
             + E    A  GTTAEI  +R  +D  I V+     G+QRF++      ++G+   +VQ
Sbjct: 141 VQERE----AQFGTTAEIYAYREEQDFGIEVVKVKAIGRQRFKVLEIRTQSDGIQQAKVQ 200

Query: 200 IIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFTSRDEEDDSASNSEESF 259
           I+ E +   T           S+VQ  SL++           F S+            S+
Sbjct: 201 ILPECVLPST----------MSAVQLESLNKCRI--------FPSK----------PVSW 260

Query: 260 ERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDSDSLGSMQSDYEKENEK 319
           E + S +  + +Q                                               
Sbjct: 261 EDQCSYKWWQKYQ----------------------------------------------- 320

Query: 320 PAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYWVYSMYDSYCLAQKAAA 379
                           KRK              H  +   WP W+YS+YD+  L  +   
Sbjct: 321 ----------------KRK-------------FHCANLTSWPRWLYSLYDAETLMDRIKK 380

Query: 380 MWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDGISYRLRREVELLKSID 439
             ++       D    NP   S+ +A+ +P+ +  R +LL+I     RLR E++++    
Sbjct: 381 QLREWDENLKEDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCT 424

Query: 440 IIQCKNC-KTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNRANGIALRGRAATEYS 499
            + CK C +T I  ++++  +S  GP+ AYVNPHGYVHE  T  +A+ + L GR +T++S
Sbjct: 441 SLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKASNLNLIGRPSTDHS 424

Query: 500 WFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQL 539
           WFPGYAWTI+ C  C + +GW FTAT +++ P+ FWG+  S L
Sbjct: 501 WFPGYAWTIAQCRICASHIGWKFTATKKDMSPQKFWGLTRSAL 424

[Close]

BLAST of MS001195 vs. ExPASy Swiss-Prot
Match: Q96SW2 (Protein cereblon OS=Homo sapiens OX=9606 GN=CRBN PE=1 SV=1)

HSP 1 Score: 163.7 bits (413), Expect = 5.8e-39
Identity = 127/488 (26.02%), Postives = 207/488 (42.42%), Query Frame = 0


Query: 57  FNSSLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFI 116
           F++SL + HTYLG   +  H     D  +   +PV   + + +L P  TLPL++     +
Sbjct: 49  FDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVL-PQVMMILIPGQTLPLQLFHPQEV 108

Query: 117 AAIERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVL---TR 176
           + +  ++       T  V+  S   + E    A  GTTAEI  +R  +D  I ++     
Sbjct: 109 SMVRNLI---QKDRTFAVLAYSNVQERE----AQFGTTAEIYAYREEQDFGIEIVKVKAI 168

Query: 177 GKQRFRLRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYT 236
           G+QRF++      ++G+   +VQI+ E +   T           S+VQ  SL++      
Sbjct: 169 GRQRFKVLELRTQSDGIQQAKVQILPECVLPST----------MSAVQLESLNKCQI--- 228

Query: 237 SCSGQFTSR--DEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQ 296
                F S+    ED  +    + +++      RK H A + S                 
Sbjct: 229 -----FPSKPVSREDQCSYKWWQKYQK------RKFHCANLTS----------------- 288

Query: 297 HAMSHLNDSDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHG 356
                                                                       
Sbjct: 289 ------------------------------------------------------------ 348

Query: 357 VSKAFWPYWVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSEST 416
                WP W+YS+YD+  L  +     ++       D    NP   S+ +A+ +P+ +  
Sbjct: 349 -----WPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVL 408

Query: 417 RQELLEIDGISYRLRREVELLKSIDIIQCKNC-KTVIAKRSDMLVMSSDGPLGAYVNPHG 476
           R +LL+I     RLR E++++     + CK C +T I  ++++  +S  GP+ AYVNPHG
Sbjct: 409 RIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHG 422

Query: 477 YVHEITTFNRANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSF 536
           YVHE  T  +A  + L GR +TE+SWFPGYAWT++ C  C + +GW FTAT +++ P+ F
Sbjct: 469 YVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKF 422

Query: 537 WGIRSSQL 539
           WG+  S L
Sbjct: 529 WGLTRSAL 422

[Close]

BLAST of MS001195 vs. ExPASy Swiss-Prot
Match: Q5R6Y2 (Protein cereblon OS=Pongo abelii OX=9601 GN=CRBN PE=2 SV=1)

HSP 1 Score: 162.5 bits (410), Expect = 1.3e-38
Identity = 126/486 (25.93%), Postives = 208/486 (42.80%), Query Frame = 0


Query: 57  FNSSLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFI 116
           F++SL + HTYLG   +  H     D  +   +PV   + + +L P  TLPL++     +
Sbjct: 36  FDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVL-PQVMMILIPGQTLPLQLFHPQEV 95

Query: 117 AAIERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVL---TR 176
           + +  ++       T  V+  S   + E    A  GTTAEI  +R  +D  I ++     
Sbjct: 96  SMVRNLI---QKDRTFAVLAYSNIQERE----AQFGTTAEIYAYREEQDFGIEIVKVKAI 155

Query: 177 GKQRFRLRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYT 236
           G+QRF++      ++G+   +VQI+ E +   T           S+VQ  SL++      
Sbjct: 156 GRQRFKVLELRTQSDGIQQAKVQILPECVLPST----------MSAVQLESLNKC----Q 215

Query: 237 SCSGQFTSRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHA 296
               +  SR+++         S++     ++RK H A + S                   
Sbjct: 216 IFPPKPVSREDQC--------SYKWWQKYQKRKFHCANLTS------------------- 275

Query: 297 MSHLNDSDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVS 356
                                                                       
Sbjct: 276 ------------------------------------------------------------ 335

Query: 357 KAFWPYWVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQ 416
              WP W+YS+YD+  L  +     ++       D    NP   S+ +A+ +P+ +  R 
Sbjct: 336 ---WPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRI 395

Query: 417 ELLEIDGISYRLRREVELLKSIDIIQCKNC-KTVIAKRSDMLVMSSDGPLGAYVNPHGYV 476
           +LL+I     RLR E++++     + CK C +T I  ++++  +S  GP+ AYVNPHGYV
Sbjct: 396 QLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYV 409

Query: 477 HEITTFNRANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWG 536
           HE  T  +A  + L GR +TE+SWFPGYAWT++ C  C + +GW FTAT +++ P+ FWG
Sbjct: 456 HETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWG 409

Query: 537 IRSSQL 539
           +  S L
Sbjct: 516 LTRSAL 409

[Close]

BLAST of MS001195 vs. ExPASy Swiss-Prot
Match: Q640S2 (Protein cereblon OS=Xenopus tropicalis OX=8364 GN=crbn PE=2 SV=1)

HSP 1 Score: 159.1 bits (401), Expect = 1.4e-37
Identity = 137/528 (25.95%), Postives = 219/528 (41.48%), Query Frame = 0


Query: 16  QILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSSLASLHTYLGEVEDAH 75
           Q++  ++EE    E++    +D +   I             F++SL + H YLG   +  
Sbjct: 20  QVISSESEEEDEMELEDAKTADSESPNI-----------INFDTSLPTSHAYLGVDMEEF 79

Query: 76  HRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIERVLTHFDTPNTIGVV 135
           H     D  +   +PV     + +L P  TLPL + +   ++ +  ++       T  V+
Sbjct: 80  HGRTLHDDDSCQQIPVLPHVQV-MLIPGQTLPLHLSRPQEVSMVRGLI---QRDRTFAVL 139

Query: 136 HVSLDSDNEKLHFANIGTTAEIRQFRRLED---GSINVLTRGKQRFRLRRRWIDAEGVPC 195
             S D    + HF   GTTAEI  +R   +    ++ V   G+QRF++      A+G+  
Sbjct: 140 AYS-DGLQREAHF---GTTAEIYAYREEHEFGIETVKVKAIGRQRFQVLETRTQADGIQV 199

Query: 196 GEVQIIQED-LPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFTSRDEEDDSASN 255
             VQI+ E  LP            P +S+Q  S SR L   T+                 
Sbjct: 200 ARVQILPERVLP-----------CPMTSLQLDSQSRHLLFPTN----------------- 259

Query: 256 SEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDSDSLGSMQSDYE 315
                                                                       
Sbjct: 260 ------------------------------------------------------------ 319

Query: 316 KENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYWVYSMYDSYCLA 375
                  P +G+S       SK + L + RR        G S   WP W+Y++YD+  L 
Sbjct: 320 ------KPVSGRS-----PQSKCQWLHKYRRRKFL----GASLTSWPSWLYALYDADSLM 379

Query: 376 QKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDGISYRLRREVEL 435
           ++      +       D    NP   S+ +A+ +P+ ++ R +LL+I     RLR E+++
Sbjct: 380 ERVKLQLHEWDENLRDDSLPANPIDFSYRVAACLPIDDALRIQLLQIGNAIQRLRCELDI 425

Query: 436 LKSIDIIQCKNC-KTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNRANGIALRGRA 495
           +     + CK+C  T I  ++++  +S  GP+ AYVNPHGYVHE  T  +A  ++L GR 
Sbjct: 440 MSKCTSLCCKHCPDTEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKAFNLSLVGRP 425

Query: 496 ATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQL 539
           +TE SWFPG+AWTI+ C  C + +GW FTA  ++L P+ FWG+  S L
Sbjct: 500 STENSWFPGFAWTIAQCRVCGSHMGWKFTAVRKDLSPQKFWGLTRSAL 425

[Close]

BLAST of MS001195 vs. ExPASy TrEMBL
Match: A0A6J1BR44 (Protein cereblon OS=Momordica charantia OX=3673 GN=LOC111004827 PE=3 SV=1)

HSP 1 Score: 1049.7 bits (2713), Expect = 4.3e-303
Identity = 537/543 (98.90%), Postives = 539/543 (99.26%), Query Frame = 0


Query: 1   MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS 60
           MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS
Sbjct: 1   MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS 60

Query: 61  LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIE 120
           LASLHTYLGEVED+HHRMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQANFIAAIE
Sbjct: 61  LASLHTYLGEVEDSHHRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQANFIAAIE 120

Query: 121 RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL 180
           RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL
Sbjct: 121 RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL 180

Query: 181 RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFT 240
           RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLS ALASYTSCS QFT
Sbjct: 181 RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSCALASYTSCSRQFT 240

Query: 241 SRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS 300
           SRDEE DSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS
Sbjct: 241 SRDEEVDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS 300

Query: 301 DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW 360
           DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW
Sbjct: 301 DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW 360

Query: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420
           VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG
Sbjct: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420

Query: 421 ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR 480
           ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR
Sbjct: 421 ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR 480

Query: 481 ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540
           ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD
Sbjct: 481 ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540

Query: 541 ATR 544
           ATR
Sbjct: 541 ATR 542

[Close]

BLAST of MS001195 vs. ExPASy TrEMBL
Match: A0A6J1BQB5 (Protein cereblon OS=Momordica charantia OX=3673 GN=LOC111004827 PE=3 SV=1)

HSP 1 Score: 1045.0 bits (2701), Expect = 1.1e-301
Identity = 537/544 (98.71%), Postives = 539/544 (99.08%), Query Frame = 0


Query: 1   MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPI-HGHGGVETFAEFTFNS 60
           MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPI HGHGGVETFAEFTFNS
Sbjct: 1   MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPISHGHGGVETFAEFTFNS 60

Query: 61  SLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAI 120
           SLASLHTYLGEVED+HHRMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQANFIAAI
Sbjct: 61  SLASLHTYLGEVEDSHHRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQANFIAAI 120

Query: 121 ERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFR 180
           ERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFR
Sbjct: 121 ERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFR 180

Query: 181 LRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQF 240
           LRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLS ALASYTSCS QF
Sbjct: 181 LRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSCALASYTSCSRQF 240

Query: 241 TSRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLND 300
           TSRDEE DSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLND
Sbjct: 241 TSRDEEVDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLND 300

Query: 301 SDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPY 360
           SDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPY
Sbjct: 301 SDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPY 360

Query: 361 WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID 420
           WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID
Sbjct: 361 WVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEID 420

Query: 421 GISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFN 480
           GISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFN
Sbjct: 421 GISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFN 480

Query: 481 RANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA 540
           RANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA
Sbjct: 481 RANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLA 540

Query: 541 DATR 544
           DATR
Sbjct: 541 DATR 543

[Close]

BLAST of MS001195 vs. ExPASy TrEMBL
Match: A0A6J1GIL0 (Protein cereblon OS=Cucurbita moschata OX=3662 GN=LOC111454509 PE=3 SV=1)

HSP 1 Score: 959.5 bits (2479), Expect = 5.9e-276
Identity = 486/543 (89.50%), Postives = 515/543 (94.84%), Query Frame = 0


Query: 1   MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRDPIHGHGGVETFAEFTFNSS 60
           MED+R+L+ ERHQIEQILQLDNEELQVEEVDYLP+SDDDRD I+ HGG E FAEFTFNSS
Sbjct: 1   MEDQRLLDNERHQIEQILQLDNEELQVEEVDYLPESDDDRDAINDHGGYEAFAEFTFNSS 60

Query: 61  LASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFIAAIE 120
           LASLHTYLGEVEDAHHRMAFLDGGAILN+PVFYLEG+ VLFPEATLPLRVIQ+NFIAAIE
Sbjct: 61  LASLHTYLGEVEDAHHRMAFLDGGAILNIPVFYLEGV-VLFPEATLPLRVIQSNFIAAIE 120

Query: 121 RVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQRFRL 180
           RVLTHFDTPNTIGVVHVS+DS +++L FANIGTTAEIRQFRRLEDGS+NVL RGKQRFRL
Sbjct: 121 RVLTHFDTPNTIGVVHVSVDSGSDRLRFANIGTTAEIRQFRRLEDGSLNVLARGKQRFRL 180

Query: 181 RRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCSGQFT 240
           RRRWID EGVPCGEVQIIQEDLPLRTPRDAFG+LAPR+++QRHSLS ALASYTSCS  FT
Sbjct: 181 RRRWIDVEGVPCGEVQIIQEDLPLRTPRDAFGDLAPRNTIQRHSLSCALASYTSCSRPFT 240

Query: 241 SRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSHLNDS 300
           SRDEEDDSASNSEESFERELSLRERKIHQAAI S+ES SDEEISGSE+EHQHAMSH NDS
Sbjct: 241 SRDEEDDSASNSEESFERELSLRERKIHQAAIGSSESCSDEEISGSEAEHQHAMSHQNDS 300

Query: 301 DSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAFWPYW 360
           DSLG + SDYEKE+EKP+PD GKSSTSA++SS+RKE + CRRNSSFN MHGVSKAF PYW
Sbjct: 301 DSLGFLHSDYEKESEKPSPDIGKSSTSAKDSSERKEFKGCRRNSSFNHMHGVSKAFLPYW 360

Query: 361 VYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420
           VYSMYDSYCLAQKAAAMWKQIVG PNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG
Sbjct: 361 VYSMYDSYCLAQKAAAMWKQIVGAPNMDGFVKNPDILSFYIASKIPVSESTRQELLEIDG 420

Query: 421 ISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEITTFNR 480
           ISYRLRRE+ELLKSID+IQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEI T  R
Sbjct: 421 ISYRLRREIELLKSIDLIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEIMTLYR 480

Query: 481 ANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540
           ANG+ALRGRA TEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD
Sbjct: 481 ANGLALRGRAETEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSSQLAD 540

Query: 541 ATR 544
           ATR
Sbjct: 541 ATR 542

[Close]

BLAST of MS001195 vs. ExPASy TrEMBL
Match: A0A5A7V9Q1 (Protein cereblon OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold82G003810 PE=3 SV=1)

HSP 1 Score: 959.1 bits (2478), Expect = 7.7e-276
Identity = 492/547 (89.95%), Postives = 512/547 (93.60%), Query Frame = 0


Query: 1   MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSD----DDRDPIHGHGGVETFAEFT 60
           MED+R+LERERHQIEQILQLDNEELQVEEVDYL DSD    DDRD I+GHGG E FAEFT
Sbjct: 1   MEDQRLLERERHQIEQILQLDNEELQVEEVDYLHDSDDDDNDDRDAINGHGGTEAFAEFT 60

Query: 61  FNSSLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFI 120
           FNSSLASLHTYLGEVEDAH RMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQ+NFI
Sbjct: 61  FNSSLASLHTYLGEVEDAHQRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQSNFI 120

Query: 121 AAIERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQ 180
           AAIERVLTHFDTPNTIGVVH+SLDSD+E+L FANIGTTAEIRQFRRLEDGS+NVL RGKQ
Sbjct: 121 AAIERVLTHFDTPNTIGVVHISLDSDSERLRFANIGTTAEIRQFRRLEDGSLNVLARGKQ 180

Query: 181 RFRLRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCS 240
           RFRLRRRWID EGVPCGEVQIIQEDLPLR PRDAFGELAPRS+VQRHSLS ALASYTSCS
Sbjct: 181 RFRLRRRWIDVEGVPCGEVQIIQEDLPLRAPRDAFGELAPRSTVQRHSLSCALASYTSCS 240

Query: 241 GQFTSRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSH 300
             FTS+DEEDDSASNSEESFERELSLRERKIHQAAIDS ES SDEE+SGSE+EHQH+MS 
Sbjct: 241 RSFTSKDEEDDSASNSEESFERELSLRERKIHQAAIDSGESCSDEEMSGSEAEHQHSMSR 300

Query: 301 LNDSDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAF 360
           LNDSDSLGSM SD EKENEKPA D GKSSTSARESSK KEL+RC+RNSSFNPMH VSKAF
Sbjct: 301 LNDSDSLGSMHSDCEKENEKPASDIGKSSTSARESSKIKELKRCQRNSSFNPMHRVSKAF 360

Query: 361 WPYWVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELL 420
           WPYWVYSMYDSYCLAQKAAAMWKQIVG PNMDGFVKNPDILSFYIASKIPVSESTRQELL
Sbjct: 361 WPYWVYSMYDSYCLAQKAAAMWKQIVGAPNMDGFVKNPDILSFYIASKIPVSESTRQELL 420

Query: 421 EIDGISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEIT 480
           EIDGISYRLRRE+ELLKSIDIIQCKNCKTVIAK SDMLVM ++GP GAYVNPHGYVHEI 
Sbjct: 421 EIDGISYRLRREIELLKSIDIIQCKNCKTVIAKHSDMLVMPNEGPFGAYVNPHGYVHEIM 480

Query: 481 TFNRANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSS 540
           T  RANG+ALRGRA TEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIR S
Sbjct: 481 TLYRANGLALRGRAETEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRCS 540

Query: 541 QLADATR 544
           QLADATR
Sbjct: 541 QLADATR 546

[Close]

BLAST of MS001195 vs. ExPASy TrEMBL
Match: A0A0A0LP38 (Protein cereblon OS=Cucumis sativus OX=3659 GN=Csa_2G373420 PE=3 SV=1)

HSP 1 Score: 958.4 bits (2476), Expect = 1.3e-275
Identity = 490/547 (89.58%), Postives = 511/547 (93.42%), Query Frame = 0


Query: 1   MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSD----DDRDPIHGHGGVETFAEFT 60
           MED+R+LERERHQIEQILQLDNEELQVEEVDYL DSD    DDRD I+GHGG E F EFT
Sbjct: 1   MEDQRLLERERHQIEQILQLDNEELQVEEVDYLHDSDDDDNDDRDAINGHGGTEAFPEFT 60

Query: 61  FNSSLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRVIQANFI 120
           FNSSLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEG+ VLFPEATLPLRVIQ+NFI
Sbjct: 61  FNSSLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGV-VLFPEATLPLRVIQSNFI 120

Query: 121 AAIERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINVLTRGKQ 180
           AAIERVLTHFDTPNTIGVVHVSLDSD+E+L FANIGTTAEIRQFRRLEDGS+NVL RGKQ
Sbjct: 121 AAIERVLTHFDTPNTIGVVHVSLDSDSERLRFANIGTTAEIRQFRRLEDGSLNVLARGKQ 180

Query: 181 RFRLRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQRHSLSRALASYTSCS 240
           RFRLRRRWID EGVPCGEVQIIQEDLPLR PRDAFGELAPRS+VQRH LS ALASYT CS
Sbjct: 181 RFRLRRRWIDVEGVPCGEVQIIQEDLPLRAPRDAFGELAPRSTVQRHGLSCALASYTPCS 240

Query: 241 GQFTSRDEEDDSASNSEESFERELSLRERKIHQAAIDSNESSSDEEISGSESEHQHAMSH 300
             FTSRDEEDDSASNSEESFERELSLRE+KIH AAIDS+ES SDEE+SGSE+EHQH+MSH
Sbjct: 241 RSFTSRDEEDDSASNSEESFERELSLREKKIHNAAIDSSESCSDEEMSGSEAEHQHSMSH 300

Query: 301 LNDSDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSFNPMHGVSKAF 360
           LNDSDSLGSM SD EKENEKPA D GKSSTSARESS+ KEL+RCRRNSSFNPMH VSKAF
Sbjct: 301 LNDSDSLGSMHSDCEKENEKPASDIGKSSTSARESSESKELKRCRRNSSFNPMHRVSKAF 360

Query: 361 WPYWVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIPVSESTRQELL 420
           WPYWVYSMYDSYCLAQKAAAMWKQIVG PNMDGFVKNPDILSFYIASKIPVSESTRQELL
Sbjct: 361 WPYWVYSMYDSYCLAQKAAAMWKQIVGAPNMDGFVKNPDILSFYIASKIPVSESTRQELL 420

Query: 421 EIDGISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYVNPHGYVHEIT 480
           EIDGISYRLRRE+ELLKSIDIIQCKNCKTVIAK SDMLVM ++GP GAYVNPHGYVHEI 
Sbjct: 421 EIDGISYRLRREIELLKSIDIIQCKNCKTVIAKHSDMLVMPNEGPFGAYVNPHGYVHEIM 480

Query: 481 TFNRANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPRSFWGIRSS 540
           T  RANG+ALRGRA TEYSWFPGYAWTISICATCETQLGWLFTATNRNLKP+SFWGIR S
Sbjct: 481 TLYRANGLALRGRAQTEYSWFPGYAWTISICATCETQLGWLFTATNRNLKPKSFWGIRCS 540

Query: 541 QLADATR 544
           QLADATR
Sbjct: 541 QLADATR 546

[Close]

BLAST of MS001195 vs. TAIR 10
Match: AT2G25740.1 (ATP-dependent protease La (LON) domain protein )

HSP 1 Score: 573.5 bits (1477), Expect = 1.7e-163
Identity = 313/557 (56.19%), Postives = 394/557 (70.74%), Query Frame = 0


Query: 1   MEDERVLERERHQIEQILQLDNEELQVEEVDYLPDSDDDRD-------PIHGH---GGVE 60
           M+DER+ ERER QIEQI +LD EELQVEEVD L DSD D +       P   H    G  
Sbjct: 1   MDDERIRERERLQIEQIRELDFEELQVEEVDDLHDSDSDDNNDDLSSFPFSSHAQASGNL 60

Query: 61  TFAEFTFNSSLASLHTYLGEVEDAHHRMAFLDGGAILNLPVFYLEGIFVLFPEATLPLRV 120
              E  FN +LASLH YLGEVED  +R++F+DGG +L +P+FYLEG+ VLFPEATLPLR+
Sbjct: 61  GDDELMFNPALASLHMYLGEVEDTQNRVSFVDGGTVLKIPLFYLEGV-VLFPEATLPLRI 120

Query: 121 IQANFIAAIERVLTHFDTPNTIGVVHVSLDSDNEKLHFANIGTTAEIRQFRRLEDGSINV 180
           IQ +F+AA+ER L   + P+TIGV+ V    +  +  +A++GTTAEIRQ+RRL DGS NV
Sbjct: 121 IQPSFLAAVERALNQANAPSTIGVIRVY--REGAQFKYASVGTTAEIRQYRRLGDGSFNV 180

Query: 181 LTRGKQRFRLRRRWIDAEGVPCGEVQIIQEDLPLRTPRDAFGELAPRSSVQ-RHSLSRAL 240
           +TRG+QRFRL+ RW D EG  CGEVQI+ ED+PLRTPRDAFG+L P S ++ R+ L  A 
Sbjct: 181 ITRGQQRFRLKHRWTDVEGFTCGEVQIVDEDVPLRTPRDAFGKLVPLSKLRGRYPLGTAS 240

Query: 241 ASYTSCSGQFTSRDEEDDSASNSEESFERELSLRERKIHQAAIDS---NESSSDEEISGS 300
            S          RD +  S +NSEESFE  LS  E+++H + +DS   N +SSD++   S
Sbjct: 241 LS-------TPLRDMDAQSEANSEESFESALSPSEKRLHYSVVDSIFCNSTSSDDDQVVS 300

Query: 301 ESEHQHAMSHLNDSDSLGSMQSDYEKENEKPAPDTGKSSTSARESSKRKELERCRRNSSF 360
            S  Q + S+     S+G + S ++ ENE      GK+  S  +  K+  L   R+N+  
Sbjct: 301 TSTVQSSGSNPYSLRSIGCLASSHDNENEDEQSAIGKTPVSQEKYQKQNRLASFRQNTDL 360

Query: 361 NPMHGVSKAFWPYWVYSMYDSYCLAQKAAAMWKQIVGVPNMDGFVKNPDILSFYIASKIP 420
           +      +AFWP+W Y M+DSY LAQ+A  +WKQIVGVPNM+ FV  PDILSF IASKIP
Sbjct: 361 SRFRMTPRAFWPFWAYRMFDSYYLAQRAVDLWKQIVGVPNMEAFVNKPDILSFSIASKIP 420

Query: 421 VSESTRQELLEIDGISYRLRREVELLKSIDIIQCKNCKTVIAKRSDMLVMSSDGPLGAYV 480
           VSES RQELLE+DG+SYRL+RE+ELL+S D ++C +C+TVIA+R DMLVMS++GPLGAYV
Sbjct: 421 VSESIRQELLELDGVSYRLQREIELLESFDRVRCIHCQTVIARRKDMLVMSNEGPLGAYV 480

Query: 481 NPHGYVHEITTFNRANGIALRGRAATEYSWFPGYAWTISICATCETQLGWLFTATNRNLK 540
           NPHGYVHEI TF +AN IALRGR   + SWFPGYAWTI+ CATCETQLGW FTATN+ LK
Sbjct: 481 NPHGYVHEIMTFYKANDIALRGRPVKKDSWFPGYAWTIANCATCETQLGWHFTATNKKLK 540

Query: 541 PRSFWGIRSSQLADATR 544
           P SFW +R SQ+AD  R
Sbjct: 541 PSSFWAVRGSQVADDMR 547

The following BLAST results are available for this feature:

BLAST of MS001195 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_022131733.1	8.9e-303	98.90	protein cereblon isoform X3 [Momordica charantia] >XP_022131734.1 protein cerebl...	[more]
XP_022131731.1	2.2e-301	98.71	protein cereblon isoform X1 [Momordica charantia] >XP_022131732.1 protein cerebl...	[more]
XP_038885492.1	4.4e-278	91.16	protein cereblon isoform X2 [Benincasa hispida]	[more]
XP_038885491.1	1.1e-276	90.99	protein cereblon isoform X1 [Benincasa hispida]	[more]
KAG6585376.1	1.2e-275	89.50	Protein cereblon, partial [Cucurbita argyrosperma subsp. sororia]	[more]

BLAST of MS001195 vs. ExPASy Swiss-Prot


Match Name	E-value	Identity	Description
Q68EH9	7.4e-42	27.05	Protein cereblon OS=Danio rerio OX=7955 GN=crbn PE=1 SV=1	[more]
Q0P564	4.5e-39	25.81	Protein cereblon OS=Bos taurus OX=9913 GN=CRBN PE=2 SV=1	[more]
Q96SW2	5.8e-39	26.02	Protein cereblon OS=Homo sapiens OX=9606 GN=CRBN PE=1 SV=1	[more]
Q5R6Y2	1.3e-38	25.93	Protein cereblon OS=Pongo abelii OX=9601 GN=CRBN PE=2 SV=1	[more]
Q640S2	1.4e-37	25.95	Protein cereblon OS=Xenopus tropicalis OX=8364 GN=crbn PE=2 SV=1	[more]

BLAST of MS001195 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A6J1BR44	4.3e-303	98.90	Protein cereblon OS=Momordica charantia OX=3673 GN=LOC111004827 PE=3 SV=1	[more]
A0A6J1BQB5	1.1e-301	98.71	Protein cereblon OS=Momordica charantia OX=3673 GN=LOC111004827 PE=3 SV=1	[more]
A0A6J1GIL0	5.9e-276	89.50	Protein cereblon OS=Cucurbita moschata OX=3662 GN=LOC111454509 PE=3 SV=1	[more]
A0A5A7V9Q1	7.7e-276	89.95	Protein cereblon OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold82G0038...	[more]
A0A0A0LP38	1.3e-275	89.58	Protein cereblon OS=Cucumis sativus OX=3659 GN=Csa_2G373420 PE=3 SV=1	[more]

BLAST of MS001195 vs. TAIR 10


Match Name	E-value	Identity	Description
AT2G25740.1	1.7e-163	56.19	ATP-dependent protease La (LON) domain protein	[more]

InterPro

Analysis Name: InterPro Annotations of Bitter gourd (TR) v1
Date Performed: 2021-10-25


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003111	Lon, substrate-binding domain	SMART	SM00464	lon_5	coord: 88..434 e-value: 1.5E-23 score: 94.2
IPR003111	Lon, substrate-binding domain	PFAM	PF02190	LON_substr_bdg	coord: 88..433 e-value: 8.6E-42 score: 143.3
IPR003111	Lon, substrate-binding domain	PROSITE	PS51787	LON_N	coord: 89..434 score: 18.924097
IPR004910	Yippee/Mis18/Cereblon	PFAM	PF03226	Yippee-Mis18	coord: 437..535 e-value: 6.9E-9 score: 35.9
None	No IPR available	GENE3D	1.20.58.1480		coord: 366..430 e-value: 8.5E-10 score: 40.2
None	No IPR available	GENE3D	2.170.150.20	Peptide methionine sulfoxide reductase.	coord: 431..543 e-value: 2.0E-38 score: 133.1
None	No IPR available	GENE3D	2.30.130.40		coord: 69..198 e-value: 7.0E-26 score: 92.3
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 236..339
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 253..271
None	No IPR available	PANTHER	PTHR14255	CEREBLON	coord: 1..539
None	No IPR available	PANTHER	PTHR14255:SF43	BNAA09G40760D PROTEIN	coord: 1..539
IPR034750	CULT domain	PROSITE	PS51788	CULT	coord: 435..542 score: 45.848305
IPR034750	CULT domain	CDD	cd15777	CRBN_C_like	coord: 438..538 e-value: 1.1225E-49 score: 164.337
IPR015947	PUA-like superfamily	SUPERFAMILY	88697	PUA domain-like	coord: 88..433

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
MS001195.1	MS001195.1	mRNA