PI0018720 (gene) Melon (PI 482460) v1

Overview


Name	PI0018720
Type	gene
Organism	Cucumis metuliferus (Melon (PI 482460) v1)
Description	Reverse transcriptase
Location	chr08: 5100426 .. 5100947 (+)
RNA-Seq Expression	PI0018720
Synteny	PI0018720

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDSpolypeptide

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGGCAAACCAAGCTCCAACTGGAGGAGCTGTACAAGTTAATAGGGTGAAAATCCCCGAACCCAAACCCTTCTGTGGGGCAAGGGACGCAAAAGCCTTGGAGAACTTCATATTTGACCTCGAACAATACTTCCGGGACTTAAACACTGTTGCGGAAGAAGCGAAAGTGACATTAGCAACGATGCACCTAGCTGAGGATGCAAAGTTGTGGTGGAGGTCCCGGTATGTCGAGATCCAAGAAGGACGATATACGATAGACACCTGGGACAGTTTAAAGAAAGAACTACGCTCACAGTTCTTCCCCGAGAATGTTGAAATCCTTGCTCGACAGAAGTTACATGAACTAAAACACACCGGTAGCATTCGGGATTATGTGAAGCAGTTTGTGGGACTGATGTTAGATATACGCGATATGTCCGAGAAAGACGAAGTTTTCTGTTTTTTCGAAGACCTTAAACCATGGGCGAAGACCAAGCTATACGAACAGAGGGTCCAAGAACTCTCATCGGCTTACGCAGCGTAG

mRNA sequence

ATGGCAAACCAAGCTCCAACTGGAGGAGCTGTACAAGTTAATAGGGTGAAAATCCCCGAACCCAAACCCTTCTGTGGGGCAAGGGACGCAAAAGCCTTGGAGAACTTCATATTTGACCTCGAACAATACTTCCGGGACTTAAACACTGTTGCGGAAGAAGCGAAAGTGACATTAGCAACGATGCACCTAGCTGAGGATGCAAAGTTGTGGTGGAGGTCCCGGTATGTCGAGATCCAAGAAGGACGATATACGATAGACACCTGGGACAGTTTAAAGAAAGAACTACGCTCACAGTTCTTCCCCGAGAATGTTGAAATCCTTGCTCGACAGAAGTTACATGAACTAAAACACACCGGTAGCATTCGGGATTATGTGAAGCAGTTTGTGGGACTGATGTTAGATATACGCGATATGTCCGAGAAAGACGAAGTTTTCTGTTTTTTCGAAGACCTTAAACCATGGGCGAAGACCAAGCTATACGAACAGAGGGTCCAAGAACTCTCATCGGCTTACGCAGCGTAG

Coding sequence (CDS)

ATGGCAAACCAAGCTCCAACTGGAGGAGCTGTACAAGTTAATAGGGTGAAAATCCCCGAACCCAAACCCTTCTGTGGGGCAAGGGACGCAAAAGCCTTGGAGAACTTCATATTTGACCTCGAACAATACTTCCGGGACTTAAACACTGTTGCGGAAGAAGCGAAAGTGACATTAGCAACGATGCACCTAGCTGAGGATGCAAAGTTGTGGTGGAGGTCCCGGTATGTCGAGATCCAAGAAGGACGATATACGATAGACACCTGGGACAGTTTAAAGAAAGAACTACGCTCACAGTTCTTCCCCGAGAATGTTGAAATCCTTGCTCGACAGAAGTTACATGAACTAAAACACACCGGTAGCATTCGGGATTATGTGAAGCAGTTTGTGGGACTGATGTTAGATATACGCGATATGTCCGAGAAAGACGAAGTTTTCTGTTTTTTCGAAGACCTTAAACCATGGGCGAAGACCAAGCTATACGAACAGAGGGTCCAAGAACTCTCATCGGCTTACGCAGCGTAG

Protein sequence

MANQAPTGGAVQVNRVKIPEPKPFCGARDAKALENFIFDLEQYFRDLNTVAEEAKVTLATMHLAEDAKLWWRSRYVEIQEGRYTIDTWDSLKKELRSQFFPENVEILARQKLHELKHTGSIRDYVKQFVGLMLDIRDMSEKDEVFCFFEDLKPWAKTKLYEQRVQELSSAYAA

Homology

[Close]

BLAST of PI0018720 vs. ExPASy TrEMBL
Match: A0A5A7UIP7 (Reverse transcriptase OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold27G00270 PE=4 SV=1)

HSP 1 Score: 315.1 bits (806), Expect = 1.8e-82
Identity = 151/173 (87.28%), Postives = 164/173 (94.80%), Query Frame = 0


Query: 1   MANQAPTGGAVQVNRVKIPEPKPFCGARDAKALENFIFDLEQYFRDLNTVAEEAKVTLAT 60
           MANQAPTGGA+ V+RVKIPEPKPFCGARDAKALEN+IFDLEQYFR  NTV EEAKVTLAT
Sbjct: 146 MANQAPTGGAIPVSRVKIPEPKPFCGARDAKALENYIFDLEQYFRATNTVTEEAKVTLAT 205

Query: 61  MHLAEDAKLWWRSRYVEIQEGRYTIDTWDSLKKELRSQFFPENVEILARQKLHELKHTGS 120
           MHL+EDAKLWWRSR+V+IQEGR TIDTWD+LK+ELRSQFFPENVEILAR+KL ELKHTGS
Sbjct: 206 MHLSEDAKLWWRSRFVDIQEGRCTIDTWDALKRELRSQFFPENVEILARRKLRELKHTGS 265

Query: 121 IRDYVKQFVGLMLDIRDMSEKDEVFCFFEDLKPWAKTKLYEQRVQELSSAYAA 174
           IR+YVKQF GLMLDIRDMSEKD+VFCF E LKPWAKTKLYEQRVQ+L+SAYAA
Sbjct: 266 IREYVKQFAGLMLDIRDMSEKDKVFCFVEGLKPWAKTKLYEQRVQDLTSAYAA 318

[Close]

BLAST of PI0018720 vs. ExPASy TrEMBL
Match: A0A5A7SW95 (Retrotrans_gag domain-containing protein OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold285G001980 PE=4 SV=1)

HSP 1 Score: 314.7 bits (805), Expect = 2.4e-82
Identity = 151/173 (87.28%), Postives = 163/173 (94.22%), Query Frame = 0


Query: 1   MANQAPTGGAVQVNRVKIPEPKPFCGARDAKALENFIFDLEQYFRDLNTVAEEAKVTLAT 60
           MANQAP GGA+ V+RVKIPEPKPFCGARDAKALEN+IFDLEQYFR  NTV EEAKVTLAT
Sbjct: 146 MANQAPAGGAIPVSRVKIPEPKPFCGARDAKALENYIFDLEQYFRATNTVTEEAKVTLAT 205

Query: 61  MHLAEDAKLWWRSRYVEIQEGRYTIDTWDSLKKELRSQFFPENVEILARQKLHELKHTGS 120
           MHL+EDAKLWWRSR+V+IQEGR TIDTWD+LK+ELRSQFFPENVEILARQKL ELKHTGS
Sbjct: 206 MHLSEDAKLWWRSRFVDIQEGRCTIDTWDALKRELRSQFFPENVEILARQKLRELKHTGS 265

Query: 121 IRDYVKQFVGLMLDIRDMSEKDEVFCFFEDLKPWAKTKLYEQRVQELSSAYAA 174
           IR+YVKQF GLMLDIRDMSEKD+VFCF E LKPWAKTKLYEQRVQ+L+SAYAA
Sbjct: 266 IREYVKQFAGLMLDIRDMSEKDKVFCFVEGLKPWAKTKLYEQRVQDLTSAYAA 318

[Close]

BLAST of PI0018720 vs. ExPASy TrEMBL
Match: A0A5D3C4R1 (Reverse transcriptase OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold110G001990 PE=4 SV=1)

HSP 1 Score: 313.2 bits (801), Expect = 7.0e-82
Identity = 150/173 (86.71%), Postives = 163/173 (94.22%), Query Frame = 0


Query: 1   MANQAPTGGAVQVNRVKIPEPKPFCGARDAKALENFIFDLEQYFRDLNTVAEEAKVTLAT 60
           MANQAP GGA+ V+RVKIPEPKPFCGARDAKALEN+IFDLEQYFR  NTV EEAKVTLAT
Sbjct: 146 MANQAPAGGAIPVSRVKIPEPKPFCGARDAKALENYIFDLEQYFRATNTVTEEAKVTLAT 205

Query: 61  MHLAEDAKLWWRSRYVEIQEGRYTIDTWDSLKKELRSQFFPENVEILARQKLHELKHTGS 120
           MHL+EDAKLWWRSR+V+IQEGR TIDTWD+LK+ELRSQFFPENVEILAR+KL ELKHTGS
Sbjct: 206 MHLSEDAKLWWRSRFVDIQEGRCTIDTWDALKRELRSQFFPENVEILARRKLRELKHTGS 265

Query: 121 IRDYVKQFVGLMLDIRDMSEKDEVFCFFEDLKPWAKTKLYEQRVQELSSAYAA 174
           IR+YVKQF GLMLDIRDMSEKD+VFCF E LKPWAKTKLYEQRVQ+L+SAYAA
Sbjct: 266 IREYVKQFAGLMLDIRDMSEKDKVFCFVEGLKPWAKTKLYEQRVQDLTSAYAA 318

[Close]

BLAST of PI0018720 vs. ExPASy TrEMBL
Match: A0A5D3BRZ6 (Reverse transcriptase OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold113G00060 PE=4 SV=1)

HSP 1 Score: 313.2 bits (801), Expect = 7.0e-82
Identity = 150/173 (86.71%), Postives = 163/173 (94.22%), Query Frame = 0


Query: 1   MANQAPTGGAVQVNRVKIPEPKPFCGARDAKALENFIFDLEQYFRDLNTVAEEAKVTLAT 60
           MANQAP GGA+ V+RVKIPEPKPFCGARDAKALEN+IFDLEQYFR  NTV EEAKVTLAT
Sbjct: 146 MANQAPAGGAIPVSRVKIPEPKPFCGARDAKALENYIFDLEQYFRATNTVTEEAKVTLAT 205

Query: 61  MHLAEDAKLWWRSRYVEIQEGRYTIDTWDSLKKELRSQFFPENVEILARQKLHELKHTGS 120
           MHL+EDAKLWWRSR+V+IQEGR TIDTWD+LK+ELRSQFFPENVEILAR+KL ELKHTGS
Sbjct: 206 MHLSEDAKLWWRSRFVDIQEGRCTIDTWDALKRELRSQFFPENVEILARRKLRELKHTGS 265

Query: 121 IRDYVKQFVGLMLDIRDMSEKDEVFCFFEDLKPWAKTKLYEQRVQELSSAYAA 174
           IR+YVKQF GLMLDIRDMSEKD+VFCF E LKPWAKTKLYEQRVQ+L+SAYAA
Sbjct: 266 IREYVKQFAGLMLDIRDMSEKDKVFCFVEGLKPWAKTKLYEQRVQDLTSAYAA 318

[Close]

BLAST of PI0018720 vs. ExPASy TrEMBL
Match: A0A5D3DQ20 (Retrotrans_gag domain-containing protein OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold352G007440 PE=4 SV=1)

HSP 1 Score: 313.2 bits (801), Expect = 7.0e-82
Identity = 150/173 (86.71%), Postives = 163/173 (94.22%), Query Frame = 0


Query: 1   MANQAPTGGAVQVNRVKIPEPKPFCGARDAKALENFIFDLEQYFRDLNTVAEEAKVTLAT 60
           MANQAP GGA+ V+RVKIPEPKPFCGARDAKALEN+IFDLEQYFR  NTV EEAKVTLAT
Sbjct: 146 MANQAPAGGAIPVSRVKIPEPKPFCGARDAKALENYIFDLEQYFRATNTVTEEAKVTLAT 205

Query: 61  MHLAEDAKLWWRSRYVEIQEGRYTIDTWDSLKKELRSQFFPENVEILARQKLHELKHTGS 120
           MHL+EDAKLWWRSR+V+IQEGR TIDTWD+LK+ELRSQFFPENVEILAR+KL ELKHTGS
Sbjct: 206 MHLSEDAKLWWRSRFVDIQEGRCTIDTWDALKRELRSQFFPENVEILARRKLRELKHTGS 265

Query: 121 IRDYVKQFVGLMLDIRDMSEKDEVFCFFEDLKPWAKTKLYEQRVQELSSAYAA 174
           IR+YVKQF GLMLDIRDMSEKD+VFCF E LKPWAKTKLYEQRVQ+L+SAYAA
Sbjct: 266 IREYVKQFAGLMLDIRDMSEKDKVFCFVEGLKPWAKTKLYEQRVQDLTSAYAA 318

[Close]

BLAST of PI0018720 vs. NCBI nr
Match: KAA0053339.1 (reverse transcriptase [Cucumis melo var. makuwa])

HSP 1 Score: 315.1 bits (806), Expect = 3.8e-82
Identity = 151/173 (87.28%), Postives = 164/173 (94.80%), Query Frame = 0


Query: 1   MANQAPTGGAVQVNRVKIPEPKPFCGARDAKALENFIFDLEQYFRDLNTVAEEAKVTLAT 60
           MANQAPTGGA+ V+RVKIPEPKPFCGARDAKALEN+IFDLEQYFR  NTV EEAKVTLAT
Sbjct: 146 MANQAPTGGAIPVSRVKIPEPKPFCGARDAKALENYIFDLEQYFRATNTVTEEAKVTLAT 205

Query: 61  MHLAEDAKLWWRSRYVEIQEGRYTIDTWDSLKKELRSQFFPENVEILARQKLHELKHTGS 120
           MHL+EDAKLWWRSR+V+IQEGR TIDTWD+LK+ELRSQFFPENVEILAR+KL ELKHTGS
Sbjct: 206 MHLSEDAKLWWRSRFVDIQEGRCTIDTWDALKRELRSQFFPENVEILARRKLRELKHTGS 265

Query: 121 IRDYVKQFVGLMLDIRDMSEKDEVFCFFEDLKPWAKTKLYEQRVQELSSAYAA 174
           IR+YVKQF GLMLDIRDMSEKD+VFCF E LKPWAKTKLYEQRVQ+L+SAYAA
Sbjct: 266 IREYVKQFAGLMLDIRDMSEKDKVFCFVEGLKPWAKTKLYEQRVQDLTSAYAA 318

[Close]

BLAST of PI0018720 vs. NCBI nr
Match: KAA0035532.1 (uncharacterized protein E6C27_scaffold285G001980 [Cucumis melo var. makuwa])

HSP 1 Score: 314.7 bits (805), Expect = 5.0e-82
Identity = 151/173 (87.28%), Postives = 163/173 (94.22%), Query Frame = 0


Query: 1   MANQAPTGGAVQVNRVKIPEPKPFCGARDAKALENFIFDLEQYFRDLNTVAEEAKVTLAT 60
           MANQAP GGA+ V+RVKIPEPKPFCGARDAKALEN+IFDLEQYFR  NTV EEAKVTLAT
Sbjct: 146 MANQAPAGGAIPVSRVKIPEPKPFCGARDAKALENYIFDLEQYFRATNTVTEEAKVTLAT 205

Query: 61  MHLAEDAKLWWRSRYVEIQEGRYTIDTWDSLKKELRSQFFPENVEILARQKLHELKHTGS 120
           MHL+EDAKLWWRSR+V+IQEGR TIDTWD+LK+ELRSQFFPENVEILARQKL ELKHTGS
Sbjct: 206 MHLSEDAKLWWRSRFVDIQEGRCTIDTWDALKRELRSQFFPENVEILARQKLRELKHTGS 265

Query: 121 IRDYVKQFVGLMLDIRDMSEKDEVFCFFEDLKPWAKTKLYEQRVQELSSAYAA 174
           IR+YVKQF GLMLDIRDMSEKD+VFCF E LKPWAKTKLYEQRVQ+L+SAYAA
Sbjct: 266 IREYVKQFAGLMLDIRDMSEKDKVFCFVEGLKPWAKTKLYEQRVQDLTSAYAA 318

[Close]

BLAST of PI0018720 vs. NCBI nr
Match: TYK18566.1 (uncharacterized protein E5676_scaffold119G00720 [Cucumis melo var. makuwa])

HSP 1 Score: 313.2 bits (801), Expect = 1.4e-81
Identity = 150/173 (86.71%), Postives = 163/173 (94.22%), Query Frame = 0


Query: 1   MANQAPTGGAVQVNRVKIPEPKPFCGARDAKALENFIFDLEQYFRDLNTVAEEAKVTLAT 60
           MANQAP GGA+ V+RVKIPEPKPFCGARDAKALEN+IFDLEQYFR  NTV EEAKVTLAT
Sbjct: 146 MANQAPAGGAIPVSRVKIPEPKPFCGARDAKALENYIFDLEQYFRATNTVTEEAKVTLAT 205

Query: 61  MHLAEDAKLWWRSRYVEIQEGRYTIDTWDSLKKELRSQFFPENVEILARQKLHELKHTGS 120
           MHL+EDAKLWWRSR+V+IQEGR TIDTWD+LK+ELRSQFFPENVEILAR+KL ELKHTGS
Sbjct: 206 MHLSEDAKLWWRSRFVDIQEGRCTIDTWDALKRELRSQFFPENVEILARRKLRELKHTGS 265

Query: 121 IRDYVKQFVGLMLDIRDMSEKDEVFCFFEDLKPWAKTKLYEQRVQELSSAYAA 174
           IR+YVKQF GLMLDIRDMSEKD+VFCF E LKPWAKTKLYEQRVQ+L+SAYAA
Sbjct: 266 IREYVKQFAGLMLDIRDMSEKDKVFCFVEGLKPWAKTKLYEQRVQDLTSAYAA 318

[Close]

BLAST of PI0018720 vs. NCBI nr
Match: KAA0037220.1 (reverse transcriptase [Cucumis melo var. makuwa] >TYJ95897.1 reverse transcriptase [Cucumis melo var. makuwa] >TYJ99001.1 reverse transcriptase [Cucumis melo var. makuwa] >TYK01698.1 reverse transcriptase [Cucumis melo var. makuwa] >TYK02882.1 reverse transcriptase [Cucumis melo var. makuwa])

HSP 1 Score: 313.2 bits (801), Expect = 1.4e-81
Identity = 150/173 (86.71%), Postives = 163/173 (94.22%), Query Frame = 0


Query: 1   MANQAPTGGAVQVNRVKIPEPKPFCGARDAKALENFIFDLEQYFRDLNTVAEEAKVTLAT 60
           MANQAP GGA+ V+RVKIPEPKPFCGARDAKALEN+IFDLEQYFR  NTV EEAKVTLAT
Sbjct: 146 MANQAPAGGAIPVSRVKIPEPKPFCGARDAKALENYIFDLEQYFRATNTVTEEAKVTLAT 205

Query: 61  MHLAEDAKLWWRSRYVEIQEGRYTIDTWDSLKKELRSQFFPENVEILARQKLHELKHTGS 120
           MHL+EDAKLWWRSR+V+IQEGR TIDTWD+LK+ELRSQFFPENVEILAR+KL ELKHTGS
Sbjct: 206 MHLSEDAKLWWRSRFVDIQEGRCTIDTWDALKRELRSQFFPENVEILARRKLRELKHTGS 265

Query: 121 IRDYVKQFVGLMLDIRDMSEKDEVFCFFEDLKPWAKTKLYEQRVQELSSAYAA 174
           IR+YVKQF GLMLDIRDMSEKD+VFCF E LKPWAKTKLYEQRVQ+L+SAYAA
Sbjct: 266 IREYVKQFAGLMLDIRDMSEKDKVFCFVEGLKPWAKTKLYEQRVQDLTSAYAA 318

[Close]

BLAST of PI0018720 vs. NCBI nr
Match: KAA0063412.1 (reverse transcriptase [Cucumis melo var. makuwa])

HSP 1 Score: 313.2 bits (801), Expect = 1.4e-81
Identity = 150/173 (86.71%), Postives = 163/173 (94.22%), Query Frame = 0


Query: 1   MANQAPTGGAVQVNRVKIPEPKPFCGARDAKALENFIFDLEQYFRDLNTVAEEAKVTLAT 60
           MANQAP GGA+ V+RVKIPEPKPFCGARDAKALEN+IFDLEQYFR  NTV EEAKVTLAT
Sbjct: 146 MANQAPAGGAIPVSRVKIPEPKPFCGARDAKALENYIFDLEQYFRATNTVTEEAKVTLAT 205

Query: 61  MHLAEDAKLWWRSRYVEIQEGRYTIDTWDSLKKELRSQFFPENVEILARQKLHELKHTGS 120
           MHL+EDAKLWWRSR+V+IQEGR TIDTWD+LK+ELRSQFFPENVEILAR+KL ELKHTGS
Sbjct: 206 MHLSEDAKLWWRSRFVDIQEGRCTIDTWDALKRELRSQFFPENVEILARRKLRELKHTGS 265

Query: 121 IRDYVKQFVGLMLDIRDMSEKDEVFCFFEDLKPWAKTKLYEQRVQELSSAYAA 174
           IR+YVKQF GLMLDIRDMSEKD+VFCF E LKPWAKTKLYEQRVQ+L+SAYAA
Sbjct: 266 IREYVKQFAGLMLDIRDMSEKDKVFCFVEGLKPWAKTKLYEQRVQDLTSAYAA 318

The following BLAST results are available for this feature:

BLAST of PI0018720 vs.


Match Name	E-value	Identity	Description

BLAST of PI0018720 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A5A7UIP7	1.8e-82	87.28	Reverse transcriptase OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold27...	[more]
A0A5A7SW95	2.4e-82	87.28	Retrotrans_gag domain-containing protein OS=Cucumis melo var. makuwa OX=1194695 ...	[more]
A0A5D3C4R1	7.0e-82	86.71	Reverse transcriptase OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold11...	[more]
A0A5D3BRZ6	7.0e-82	86.71	Reverse transcriptase OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold11...	[more]
A0A5D3DQ20	7.0e-82	86.71	Retrotrans_gag domain-containing protein OS=Cucumis melo var. makuwa OX=1194695 ...	[more]

BLAST of PI0018720 vs. NCBI nr


Match Name	E-value	Identity	Description
KAA0053339.1	3.8e-82	87.28	reverse transcriptase [Cucumis melo var. makuwa]	[more]
KAA0035532.1	5.0e-82	87.28	uncharacterized protein E6C27_scaffold285G001980 [Cucumis melo var. makuwa]	[more]
TYK18566.1	1.4e-81	86.71	uncharacterized protein E5676_scaffold119G00720 [Cucumis melo var. makuwa]	[more]
KAA0037220.1	1.4e-81	86.71	reverse transcriptase [Cucumis melo var. makuwa] >TYJ95897.1 reverse transcripta...	[more]
KAA0063412.1	1.4e-81	86.71	reverse transcriptase [Cucumis melo var. makuwa]	[more]

BLAST of PI0018720 vs. NCBI nr


Match Name	E-value	Identity	Description

InterPro

Analysis Name: InterPro Annotations of Melon (PI 482460) v1
Date Performed: 2021-10-25


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR005162	Retrotransposon gag domain	PFAM	PF03732	Retrotrans_gag	coord: 58..150 e-value: 2.1E-15 score: 56.7
None	No IPR available	PANTHER	PTHR34482:SF18	RETROTRANSPOSON GAG DOMAIN, ASPARTIC PEPTIDASE DOMAIN PROTEIN-RELATED	coord: 13..170
None	No IPR available	PANTHER	PTHR34482	DNA DAMAGE-INDUCIBLE PROTEIN 1-LIKE	coord: 13..170

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
PI0018720.1	PI0018720.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0015074	DNA integration
biological_process	GO:0090305	nucleic acid phosphodiester bond hydrolysis
biological_process	GO:0006508	proteolysis
biological_process	GO:0006278	RNA-dependent DNA biosynthetic process
molecular_function	GO:0004190	aspartic-type endopeptidase activity
molecular_function	GO:0004519	endonuclease activity
molecular_function	GO:0003676	nucleic acid binding
molecular_function	GO:0003964	RNA-directed DNA polymerase activity
molecular_function	GO:0008270	zinc ion binding