Lcy08g016300 (gene) Sponge gourd (P93075) v1

Overview


Name	Lcy08g016300
Type	gene
Organism	Luffa cylindrica cv. P93075 (Sponge gourd (P93075) v1)
Description	RNase H domain-containing protein
Location	Chr08: 46867041 .. 46868058 (-)
RNA-Seq Expression	Lcy08g016300
Synteny	Lcy08g016300

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: polypeptideexonCDS

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGGGAAGTTTTGCAAATGGCCAAATTTTTTGAACCACAATCTTGAGTTTGCCAAACATTGTGACTGAAAATGAAAAGGAATGAAATGATAATTTTTGATACCCTTAATAAGGTAGGGTCAAATATTATTTTTATATTTATGAAACTAGTTATAAATTATAAAAAAAAAAATACTGGTTTCAATTATACTTCTGAATTTTCAAAAGTTTCATTTTAGTTCTCAAAATTTGAATTTTGTTTCGAAACAATCCTTGAAGACATTTTTTTTTGTTAAATTTATGGATGGAAAATGAAGGATTTGCATATGTATTGTTGCTTATGTGAACATATTTTAACATATACGTGAAGAAAACAATAAAAATACATGCAAACACATGTTTTTCGTTCATAAATTTAATAGAAAATGTCTCTCACGACCTTTTGGAAACAAACTTAAACTTCAAGGGCTAAAATGAACTCAGATGCCTCTTGGAATGAGGCCCAAGGTTGTGGAGGTGTTGGTTGGATAATCCGTGACTCCCAAGGATCTTTGGTGGTTGCGGGCAGCAAAACTTTACACAGAAATTGGCCGATTGATATGCTTGAAGCGTTTGCGACGATCAAGGAAGGGTTGTTGAATTTCCTTAATCTCAATCCTCCCCCCCATATCGGCTTGATCGTGGAATCTGACGCTGAGGACCTGATCAGCTCGCTTATCTCTTCATCTCCCAATCTCACTGAAATTCACTTCATCTTGGATGAAGTGAGATCGATCGCTAGCACCATCAAGGATATCTGCTTCCTCTGGTGCCCTAGATCTTCAAATGGTGTCGCGCATTCTCTCGCGCGTTTTGCTTCTCGAGTGTTGTCGCCTCGACCTCCTTCAAATGAAGCCGGTGGCAGTTTGTCTGTTTATTTGGATTCTTCGCAATTTCCCTCTTCTTCTTCCCCGGAAGTCTGTTTTTTTGGTAGGGAATCGTCTTTGCCTTTCTGGTTGTCCTCTGCTATAATCGAGGACCTTGTTTGTTGTGGTGGTTAG

mRNA sequence

ATGGGAAATGCCTCTTGGAATGAGGCCCAAGGTTGTGGAGGTGTTGGTTGGATAATCCGTGACTCCCAAGGATCTTTGGTGGTTGCGGGCAGCAAAACTTTACACAGAAATTGGCCGATTGATATGCTTGAAGCGTTTGCGACGATCAAGGAAGGGTTGTTGAATTTCCTTAATCTCAATCCTCCCCCCCATATCGGCTTGATCGTGGAATCTGACGCTGAGGACCTGATCAGCTCGCTTATCTCTTCATCTCCCAATCTCACTGAAATTCACTTCATCTTGGATGAAGTGAGATCGATCGCTAGCACCATCAAGGATATCTGCTTCCTCTGGTGCCCTAGATCTTCAAATGGTGTCGCGCATTCTCTCGCGCGTTTTGCTTCTCGAGTGTTGTCGCCTCGACCTCCTTCAAATGAAGCCGGTGGCAGTTTGTCTGTTTATTTGGATTCTTCGCAATTTCCCTCTTCTTCTTCCCCGGAAGTCTGTTTTTTTGGTAGGGAATCGTCTTTGCCTTTCTGGTTGTCCTCTGCTATAATCGAGGACCTTGTTTGTTGTGGTGGTTAG

Coding sequence (CDS)

ATGGGAAATGCCTCTTGGAATGAGGCCCAAGGTTGTGGAGGTGTTGGTTGGATAATCCGTGACTCCCAAGGATCTTTGGTGGTTGCGGGCAGCAAAACTTTACACAGAAATTGGCCGATTGATATGCTTGAAGCGTTTGCGACGATCAAGGAAGGGTTGTTGAATTTCCTTAATCTCAATCCTCCCCCCCATATCGGCTTGATCGTGGAATCTGACGCTGAGGACCTGATCAGCTCGCTTATCTCTTCATCTCCCAATCTCACTGAAATTCACTTCATCTTGGATGAAGTGAGATCGATCGCTAGCACCATCAAGGATATCTGCTTCCTCTGGTGCCCTAGATCTTCAAATGGTGTCGCGCATTCTCTCGCGCGTTTTGCTTCTCGAGTGTTGTCGCCTCGACCTCCTTCAAATGAAGCCGGTGGCAGTTTGTCTGTTTATTTGGATTCTTCGCAATTTCCCTCTTCTTCTTCCCCGGAAGTCTGTTTTTTTGGTAGGGAATCGTCTTTGCCTTTCTGGTTGTCCTCTGCTATAATCGAGGACCTTGTTTGTTGTGGTGGTTAG

Protein sequence

MGNASWNEAQGCGGVGWIIRDSQGSLVVAGSKTLHRNWPIDMLEAFATIKEGLLNFLNLNPPPHIGLIVESDAEDLISSLISSSPNLTEIHFILDEVRSIASTIKDICFLWCPRSSNGVAHSLARFASRVLSPRPPSNEAGGSLSVYLDSSQFPSSSSPEVCFFGRESSLPFWLSSAIIEDLVCCGG

Homology

[Close]

BLAST of Lcy08g016300 vs. ExPASy TrEMBL
Match: A0A6J1DNV9 (uncharacterized protein LOC111022403 OS=Momordica charantia OX=3673 GN=LOC111022403 PE=4 SV=1)

HSP 1 Score: 74.7 bits (182), Expect = 4.5e-10
Identity = 46/128 (35.94%), Postives = 76/128 (59.38%), Query Frame = 0


Query: 3   NASWNEAQGCGGVGWIIRDSQGSLVVAGSKTLHRNWPIDMLEAFATIKEGLLNFLNLN-- 62
           +ASW+++   GG+GWIIR   G +V+AG++ +     + +LEA A I EGL N  NL   
Sbjct: 84  DASWSDSTHRGGIGWIIRSWDGDIVLAGNRFVEACNNVKLLEASA-ILEGLRNLTNLGVL 143

Query: 63  PPPHIGLIVESDAEDLISSLISSSPNLTEIHFILDEVRSIASTIKDICFLWCPRSSNGVA 122
            P HI    E+D+ ++ S L     +LT+  ++++E+ ++  + + + F    R +NG A
Sbjct: 144 RPLHI----ETDSAEVESLLNRKREDLTKTGWVVEEILNLRDSCEILAFAKVGRETNGCA 203

Query: 123 HSLARFAS 129
           HSLA+ AS
Sbjct: 204 HSLAQRAS 206

[Close]

BLAST of Lcy08g016300 vs. ExPASy TrEMBL
Match: A0A6D2I187 (RNase H domain-containing protein OS=Microthlaspi erraticum OX=1685480 GN=MERR_LOCUS6222 PE=4 SV=1)

HSP 1 Score: 70.1 bits (170), Expect = 1.1e-08
Identity = 49/128 (38.28%), Postives = 69/128 (53.91%), Query Frame = 0


Query: 5   SWNEAQGCGGVGWIIRDSQGSLVVAGSKTLHRNWPIDMLEAFATIKEGLLNFLNLNPPPH 64
           SW +    GG+GWI+ D  GS V  G  T  R     M EA A I+  L + L L     
Sbjct: 37  SWCKKTKTGGMGWILLDGAGSEVSRGHATERRITSALMAEALA-IRSALNHALELG---I 96

Query: 65  IGLIVESDAEDLISSLISSSPNLTEIHFILDEVRSIASTIKDICFLWCPRSSNGVAHSLA 124
             L + SDA DLI  +IS+   L EI+ IL ++ ++AS    I F + PRS N +A  +A
Sbjct: 97  TDLQINSDALDLI-RVISTQEQLKEIYEILFDIHALASMFSSISFSYIPRSENKIADEIA 156

Query: 125 RFASRVLS 133
           + A+R++S
Sbjct: 157 KSANRLIS 159

[Close]

BLAST of Lcy08g016300 vs. ExPASy TrEMBL
Match: A0A6J5UE59 (Reverse transcriptase domain-containing protein OS=Prunus armeniaca OX=36596 GN=CURHAP_LOCUS23353 PE=4 SV=1)

HSP 1 Score: 68.2 bits (165), Expect = 4.3e-08
Identity = 45/128 (35.16%), Postives = 75/128 (58.59%), Query Frame = 0


Query: 3    NASWNEAQGCGGVGWIIRDSQGSLVVAGSK-TLHRNWPIDMLEAFATIKEGLLNFLNLNP 62
            +A+W+  +  GGVGW+IRDS G L+ AG +  LH +  I M+E  A I+  L    N + 
Sbjct: 1140 DAAWSAQRMGGGVGWVIRDSFGLLLCAGGQGDLHGSSAI-MMELLA-IRHALSECANFH- 1199

Query: 63   PPHIGLIVESDAEDLISSLISSSPNLTEIHFILDEVRSIASTIKDICFLWCPRSSNGVAH 122
                 +IVESD++  I  L   +   +++  I+ ++R + +++  + F++ PRS N  AH
Sbjct: 1200 --LTDIIVESDSQKGILMLNGRATVDSDLEGIVFDIRQLVASLSRVSFVFAPRSCNQAAH 1259

Query: 123  SLARFASR 130
            S+A FAS+
Sbjct: 1260 SVAGFASK 1262

[Close]

BLAST of Lcy08g016300 vs. ExPASy TrEMBL
Match: A0A6J5UF50 (Uncharacterized protein OS=Prunus armeniaca OX=36596 GN=CURHAP_LOCUS23354 PE=4 SV=1)

HSP 1 Score: 68.2 bits (165), Expect = 4.3e-08
Identity = 45/128 (35.16%), Postives = 75/128 (58.59%), Query Frame = 0


Query: 3   NASWNEAQGCGGVGWIIRDSQGSLVVAGSK-TLHRNWPIDMLEAFATIKEGLLNFLNLNP 62
           +A+W+  +  GGVGW+IRDS G L+ AG +  LH +  I M+E  A I+  L    N + 
Sbjct: 272 DAAWSAQRMGGGVGWVIRDSFGLLLCAGGQGDLHGSSAI-MMELLA-IRHALSECANFH- 331

Query: 63  PPHIGLIVESDAEDLISSLISSSPNLTEIHFILDEVRSIASTIKDICFLWCPRSSNGVAH 122
                +IVESD++  I  L   +   +++  I+ ++R + +++  + F++ PRS N  AH
Sbjct: 332 --LTDIIVESDSQKGILMLNGRATVDSDLEGIVFDIRQLVASLSRVSFVFAPRSCNQAAH 391

Query: 123 SLARFASR 130
           S+A FAS+
Sbjct: 392 SVAGFASK 394

[Close]

BLAST of Lcy08g016300 vs. ExPASy TrEMBL
Match: A0A6J5WPU6 (Reverse transcriptase domain-containing protein OS=Prunus armeniaca OX=36596 GN=ORAREDHAP_LOCUS20372 PE=4 SV=1)

HSP 1 Score: 66.6 bits (161), Expect = 1.2e-07
Identity = 44/128 (34.38%), Postives = 74/128 (57.81%), Query Frame = 0


Query: 3   NASWNEAQGCGGVGWIIRDSQGSLVVAGSK-TLHRNWPIDMLEAFATIKEGLLNFLNLNP 62
           +A+W+  +  GGVGW+IRDS G L+ AG +  LH +  I M+E  A I+  L    N + 
Sbjct: 809 DAAWSAQRMGGGVGWVIRDSFGLLLCAGGQGDLHGSSAI-MMELLA-IRHALSECANFH- 868

Query: 63  PPHIGLIVESDAEDLISSLISSSPNLTEIHFILDEVRSIASTIKDICFLWCPRSSNGVAH 122
                +IVESD++  I  L   +   +++  I+ ++R + +++  + F++ PRS N  AH
Sbjct: 869 --LTDIIVESDSQKGILMLNGRATVDSDLEGIVFDIRQLVASLSRVSFVFAPRSCNQAAH 928

Query: 123 SLARFASR 130
           S+A F S+
Sbjct: 929 SVAGFVSK 931

[Close]

BLAST of Lcy08g016300 vs. NCBI nr
Match: XP_022155262.1 (uncharacterized protein LOC111022403 [Momordica charantia])

HSP 1 Score: 74.7 bits (182), Expect = 9.4e-10
Identity = 46/128 (35.94%), Postives = 76/128 (59.38%), Query Frame = 0


Query: 3   NASWNEAQGCGGVGWIIRDSQGSLVVAGSKTLHRNWPIDMLEAFATIKEGLLNFLNLN-- 62
           +ASW+++   GG+GWIIR   G +V+AG++ +     + +LEA A I EGL N  NL   
Sbjct: 84  DASWSDSTHRGGIGWIIRSWDGDIVLAGNRFVEACNNVKLLEASA-ILEGLRNLTNLGVL 143

Query: 63  PPPHIGLIVESDAEDLISSLISSSPNLTEIHFILDEVRSIASTIKDICFLWCPRSSNGVA 122
            P HI    E+D+ ++ S L     +LT+  ++++E+ ++  + + + F    R +NG A
Sbjct: 144 RPLHI----ETDSAEVESLLNRKREDLTKTGWVVEEILNLRDSCEILAFAKVGRETNGCA 203

Query: 123 HSLARFAS 129
           HSLA+ AS
Sbjct: 204 HSLAQRAS 206

[Close]

BLAST of Lcy08g016300 vs. NCBI nr
Match: KAF7826352.1 (uncharacterized protein G2W53_017516 [Senna tora])

HSP 1 Score: 72.0 bits (175), Expect = 6.1e-09
Identity = 42/121 (34.71%), Postives = 68/121 (56.20%), Query Frame = 0


Query: 10  QGCGGVGWIIRDSQGSLVVAGSKTLHRNWPIDMLEAFATIKEGLLNFLNLNPPPHIGLIV 69
           QG GG+G ++R+ QG  + A +K +      ++LEA+A + EGL    NL       +I+
Sbjct: 16  QGKGGIGCVVRNFQGRCLAAFAKRMQNIESAELLEAYAFL-EGLELAKNLRCD---NIIL 75

Query: 70  ESDAEDLISSLISSSPNLTEIHFILDEVRSIASTIKDICFLWCPRSSNGVAHSLARFASR 129
           E DA+ ++  +  SS NL+ +  I+D++R        +   W PR+SN VA S+A FAS 
Sbjct: 76  EGDAKKVVDLIHGSSQNLSHLGMIVDDIRKGMKNFSRVKVQWVPRNSNAVADSIANFASN 132

Query: 130 V 131
           +
Sbjct: 136 L 132

[Close]

BLAST of Lcy08g016300 vs. NCBI nr
Match: KAF7842590.1 (putative RNA-directed DNA polymerase [Senna tora])

HSP 1 Score: 70.9 bits (172), Expect = 1.4e-08
Identity = 42/122 (34.43%), Postives = 67/122 (54.92%), Query Frame = 0


Query: 10  QGCGGVGWIIRDSQGSLVVAGSKTLHRNWPIDMLEAFATIKEGLLNFLNLNPPPHIGLIV 69
           QG GG+G ++R+ QG  + A +K +      ++LEAFA + EGL    NL       +I+
Sbjct: 380 QGKGGIGCVVRNFQGRCLAAFAKRMKNIESAELLEAFAFL-EGLELAKNLRCD---NIIL 439

Query: 70  ESDAEDLISSLISSSPNLTEIHFILDEVRSIASTIKDICFLWCPRSSNGVAHSLARFASR 129
           E DA+ ++  +  SS NL+ +  ++D++R        +   W PR+SN VA  +A FA  
Sbjct: 440 EGDAKKVVDLIHGSSQNLSHLGMLVDDIRKGMKNFSRVKVQWVPRNSNAVADRIANFACT 497

Query: 130 VL 132
           VL
Sbjct: 500 VL 497

[Close]

BLAST of Lcy08g016300 vs. NCBI nr
Match: CAA7018987.1 (unnamed protein product [Microthlaspi erraticum])

HSP 1 Score: 70.1 bits (170), Expect = 2.3e-08
Identity = 49/128 (38.28%), Postives = 69/128 (53.91%), Query Frame = 0


Query: 5   SWNEAQGCGGVGWIIRDSQGSLVVAGSKTLHRNWPIDMLEAFATIKEGLLNFLNLNPPPH 64
           SW +    GG+GWI+ D  GS V  G  T  R     M EA A I+  L + L L     
Sbjct: 37  SWCKKTKTGGMGWILLDGAGSEVSRGHATERRITSALMAEALA-IRSALNHALELG---I 96

Query: 65  IGLIVESDAEDLISSLISSSPNLTEIHFILDEVRSIASTIKDICFLWCPRSSNGVAHSLA 124
             L + SDA DLI  +IS+   L EI+ IL ++ ++AS    I F + PRS N +A  +A
Sbjct: 97  TDLQINSDALDLI-RVISTQEQLKEIYEILFDIHALASMFSSISFSYIPRSENKIADEIA 156

Query: 125 RFASRVLS 133
           + A+R++S
Sbjct: 157 KSANRLIS 159

[Close]

BLAST of Lcy08g016300 vs. NCBI nr
Match: KAF7825130.1 (putative RNA-directed DNA polymerase [Senna tora])

HSP 1 Score: 68.6 bits (166), Expect = 6.7e-08
Identity = 39/121 (32.23%), Postives = 69/121 (57.02%), Query Frame = 0


Query: 10  QGCGGVGWIIRDSQGSLVVAGSKTLHRNWPIDMLEAFATIKEGLLNFLNLNPPPHIGLIV 69
           QG  G+  ++R+ QG  + A +K +     +D+LEA+A + EGL     L       +I+
Sbjct: 529 QGKSGISCVVRNYQGRCLAAFAKKIPNVDEVDLLEAYAFL-EGLELAKRLRCE---NIIL 588

Query: 70  ESDAEDLISSLISSSPNLTEIHFILDEVRSIASTIKDICFLWCPRSSNGVAHSLARFASR 129
           E DA+ ++  + SS+PNL+ +  ++D++R   ++   +   W PR+SN VAH +A FA  
Sbjct: 589 EGDAKKVVDWVNSSAPNLSILGMLIDDIRYAMASFSTVRVQWTPRNSNLVAHRIANFACE 645

Query: 130 V 131
           +
Sbjct: 649 I 645

[Close]

BLAST of Lcy08g016300 vs. TAIR 10
Match: AT4G09490.1 (Polynucleotidyl transferase, ribonuclease H-like superfamily protein )

HSP 1 Score: 50.4 bits (119), Expect = 1.8e-06
Identity = 37/126 (29.37%), Postives = 64/126 (50.79%), Query Frame = 0


Query: 3   NASWNEAQGCGGVGWIIRDSQGSLVVAGSKTLHRNWPIDMLEAFATIKEGLLNFLNLNPP 62
           +A+W       G GW+IR+    L     ++  RN  + ++       E +  FL L   
Sbjct: 36  DAAWKHETKDVGFGWVIRNCP-ELTALHYQSAARNVRLPLM------AEAIALFLALQYA 95

Query: 63  PHIG---LIVESDAEDLISSLISSSPNLTEIHFILDEVRSIASTIKDICFLWCPRSSNGV 122
             IG   L + SD++ LI+++ S SP+ TE + I+ ++ +++    D+ F + PRS N V
Sbjct: 96  QSIGITKLSMASDSQQLITAITSESPS-TEFYGIIFDILNLSLGFADVSFSFVPRSENRV 153

Query: 123 AHSLAR 126
           A  LA+
Sbjct: 156 ADELAK 153

[Close]

BLAST of Lcy08g016300 vs. TAIR 10
Match: AT5G65005.1 (Polynucleotidyl transferase, ribonuclease H-like superfamily protein )

HSP 1 Score: 42.0 bits (97), Expect = 6.3e-04
Identity = 34/125 (27.20%), Postives = 56/125 (44.80%), Query Frame = 0


Query: 3   NASWNEAQGCGGVGWIIRDSQGSLVVAGSKTLHRNWPIDMLEAFATIKEGLLNFLNLNPP 62
           +AS +E     G+GWI+R+SQG+++  G          +  E    I     ++      
Sbjct: 118 DASHHERNTVSGLGWILRNSQGTVIECGMGKFQGRMTTEEAECSTLIWAIQASY----GF 177

Query: 63  PHIGLIVESDAEDLISSLISSSPNLTEIHFILDEVRSIASTIKDICFLWCPRSSNGVAHS 122
            H  +I E D + +   + + S N    HF LD ++S   + + I F +  R  NG A  
Sbjct: 178 GHKKVIFEGDNQTITRMINTKSSNPRLQHF-LDTIQSWIPSFESIEFSFKHREQNGCADF 237

Query: 123 LARFA 128
           LA+ A
Sbjct: 238 LAKQA 237

The following BLAST results are available for this feature:

BLAST of Lcy08g016300 vs.


Match Name	E-value	Identity	Description

BLAST of Lcy08g016300 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A6J1DNV9	4.5e-10	35.94	uncharacterized protein LOC111022403 OS=Momordica charantia OX=3673 GN=LOC111022...	[more]
A0A6D2I187	1.1e-08	38.28	RNase H domain-containing protein OS=Microthlaspi erraticum OX=1685480 GN=MERR_L...	[more]
A0A6J5UE59	4.3e-08	35.16	Reverse transcriptase domain-containing protein OS=Prunus armeniaca OX=36596 GN=...	[more]
A0A6J5UF50	4.3e-08	35.16	Uncharacterized protein OS=Prunus armeniaca OX=36596 GN=CURHAP_LOCUS23354 PE=4 S...	[more]
A0A6J5WPU6	1.2e-07	34.38	Reverse transcriptase domain-containing protein OS=Prunus armeniaca OX=36596 GN=...	[more]

BLAST of Lcy08g016300 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_022155262.1	9.4e-10	35.94	uncharacterized protein LOC111022403 [Momordica charantia]	[more]
KAF7826352.1	6.1e-09	34.71	uncharacterized protein G2W53_017516 [Senna tora]	[more]
KAF7842590.1	1.4e-08	34.43	putative RNA-directed DNA polymerase [Senna tora]	[more]
CAA7018987.1	2.3e-08	38.28	unnamed protein product [Microthlaspi erraticum]	[more]
KAF7825130.1	6.7e-08	32.23	putative RNA-directed DNA polymerase [Senna tora]	[more]

BLAST of Lcy08g016300 vs. TAIR 10


Match Name	E-value	Identity	Description
AT4G09490.1	1.8e-06	29.37	Polynucleotidyl transferase, ribonuclease H-like superfamily protein	[more]
AT5G65005.1	6.3e-04	27.20	Polynucleotidyl transferase, ribonuclease H-like superfamily protein	[more]

InterPro

Analysis Name: InterPro Annotations of Sponge gourd (P93075) v1
Date Performed: 2021-12-06


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR036397	Ribonuclease H superfamily	GENE3D	3.30.420.10		coord: 2..130 e-value: 1.5E-7 score: 33.4
IPR002156	Ribonuclease H domain	PFAM	PF13456	RVT_3	coord: 3..127 e-value: 2.1E-15 score: 56.6
None	No IPR available	PANTHER	PTHR33033:SF67	SUBFAMILY NOT NAMED	coord: 4..129
None	No IPR available	PANTHER	PTHR33033	POLYNUCLEOTIDYL TRANSFERASE, RIBONUCLEASE H-LIKE SUPERFAMILY PROTEIN-RELATED	coord: 4..129
IPR044730	Ribonuclease H-like domain, plant type	CDD	cd06222	RNase_H_like	coord: 4..125 e-value: 3.65846E-10 score: 53.0868
IPR012337	Ribonuclease H-like superfamily	SUPERFAMILY	53098	Ribonuclease H-like	coord: 4..130

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
Lcy08g016300.1	Lcy08g016300.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
molecular_function	GO:0003676	nucleic acid binding
molecular_function	GO:0004523	RNA-DNA hybrid ribonuclease activity