Cucsat.G2498 (gene) Cucumber (B10) v3

Overview


Name	Cucsat.G2498
Type	gene
Organism	Cucumis sativus L. var. sativus cv B10 (Cucumber (B10) v3)
Description	Transcription factor bHLH35-like protein
Location	ctg1002: 5945923 .. 5946958 (+)
RNA-Seq Expression	Cucsat.G2498
Synteny	Cucsat.G2498

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDSpolypeptide

Hold the cursor over a type above to highlight its positions in the sequence below.

GGTAAAAAGGGGGAAAATGAAAAAAAGAAAAAAGAGAAAGAGAAAAAGTAACCTCCAACCTAATTTTTAATCCCCACATACCATATTGTCCTGTATATATATGTGTGTGTGTGTGTGTGTAAGCATAGAAGTATTTACGTACGAATGGAATAATTAAATATTATATAAGTTTTAAAGAGATGGGGTTCCTCTGTTTTTTAAATTCACATAAGAGATTGTCACAATTTCGCCTTTAAAAATACATAGAGAGCAAACTTTTTTATGCTATAAATAGACACACCCTTCATTTCAGGTCTTATTCCTCACTGACTTTTGTTTAATTGGGGAGCAAGAGCAAGTTCAAGCTTAGAGATTAACAGAGAAACAGAGATGGTTTCTACATTACAAAAGAGATTCGACTCACGTAACAAGCTACGCCTTGTTCGATCTCTACCCACTTATGAATCCTCTGTAATTCCTAAAACATTCTTCTTCTTTTTTCTTTTTTCTTTTTTTGTTATGTTTTTTTTAATCATTCTTTTTTTTTTCCCCTGTCACTTCACCTTGTTTTGGCCATTAGTTCTAATCAAGTCTTCTGTTTATGTAGGGAAGACAGAGGTGTGTGTTTTGGAATGCTGTTCTCTTCATTCATAAGCTTAAACTCAAGCTGGAAGCAATTGAGAGAGAGTACTCAAATCTACTGGACATGAAAAGAGAATATTTGAACTCAATAAAGCAATTTCATTCCTCCAAGGTCCTTTTTTCACCCCTCTTTCTGTCTCTTTAAACTATTGAAAGATATGATCTTTATAATGGGAACAAAGTAAATATAATGTTTTTATAAAAGCAGGAAGTGAAGGTTGAGAAGAATGGAGAAGAGTTTAGGGTGAAAGTGAGATGCGAAAAGGGAGGGGACAGATTGGTTTCAGTATTAGAAGCATTTGAGAAAATGGGTCTTAATGTTGTTGAAGCTAGAGTTTCATGTACTGAATGTTTTTGTATGGAGGCCACTGCTGTAGCTGAAGATCATCATCAATTGCTTAATCTCAGTGATATAACCGAAGCTATTAATGTAGCCATTGATCCCAAATTATTAGCTCCAAACCAGCATCATAATGACAGTATTCCTCACAATGATGCTCAACTTTATTAGTCACTTCCTAACCTATCAATTCAATGAAAATGTTTCTTCCATTCCAAATTCCAAACTCTCGTGTTTTTCTTTCGTTCTTTCTTTCTTTCCAATTATTCAAATTTGAAAAGAAAAAAAAAATATATATATATATATATATAGATTTGGCAATTCTTAA

Coding sequence (CDS)

ATGGTTTCTACATTACAAAAGAGATTCGACTCACGTAACAAGCTACGCCTTGTTCGATCTCTACCCACTTATGAATCCTCTGGAAGACAGAGGTGTGTGTTTTGGAATGCTGTTCTCTTCATTCATAAGCTTAAACTCAAGCTGGAAGCAATTGAGAGAGAGTACTCAAATCTACTGGACATGAAAAGAGAATATTTGAACTCAATAAAGCAATTTCATTCCTCCAAGGAAGTGAAGGTTGAGAAGAATGGAGAAGAGTTTAGGGTGAAAGTGAGATGCGAAAAGGGAGGGGACAGATTGGTTTCAGTATTAGAAGCATTTGAGAAAATGGGTCTTAATGTTGTTGAAGCTAGAGTTTCATGTACTGAATGTTTTTGTATGGAGGCCACTGCTGTAGCTGAAGATCATCATCAATTGCTTAATCTCAGTGATATAACCGAAGCTATTAATGTAGCCATTGATCCCAAATTATTAGCTCCAAACCAGCATCATAATGACAGTATTCCTCACAATGATGCTCAACTTTATTAG

Protein sequence

MVSTLQKRFDSRNKLRLVRSLPTYESSGRQRCVFWNAVLFIHKLKLKLEAIEREYSNLLDMKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVSCTECFCMEATAVAEDHHQLLNLSDITEAINVAIDPKLLAPNQHHNDSIPHNDAQLY

Homology

[Close]

BLAST of Cucsat.G2498 vs. NCBI nr
Match: XP_004134653.1 (uncharacterized protein LOC101213083 [Cucumis sativus] >KGN49320.1 hypothetical protein Csa_003445 [Cucumis sativus])

HSP 1 Score: 233 bits (594), Expect = 2.60e-76
Identity = 116/116 (100.00%), Postives = 116/116 (100.00%), Query Frame = 0


Query: 1   MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 60
           MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS
Sbjct: 61  MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 120

Query: 61  CTECFCMEATAVAEDHHQLLNLSDITEAINVAIDPKLLAPNQHHNDSIPHNDAQLY 116
           CTECFCMEATAVAEDHHQLLNLSDITEAINVAIDPKLLAPNQHHNDSIPHNDAQLY
Sbjct: 121 CTECFCMEATAVAEDHHQLLNLSDITEAINVAIDPKLLAPNQHHNDSIPHNDAQLY 176

[Close]

BLAST of Cucsat.G2498 vs. NCBI nr
Match: XP_008439723.1 (PREDICTED: uncharacterized protein LOC103484437 [Cucumis melo] >ADN34030.1 hypothetical protein [Cucumis melo subsp. melo])

HSP 1 Score: 223 bits (569), Expect = 1.62e-72
Identity = 113/116 (97.41%), Postives = 114/116 (98.28%), Query Frame = 0


Query: 1   MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 60
           MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS
Sbjct: 61  MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 120

Query: 61  CTECFCMEATAVAEDHHQLLNLSDITEAINVAIDPKLLAPNQHHNDSIPHNDAQLY 116
           CTECFCMEA AVAEDHHQLLNLSDIT+AINVAIDPKLLAPNQHHND IPHNDAQLY
Sbjct: 121 CTECFCMEAIAVAEDHHQLLNLSDITDAINVAIDPKLLAPNQHHND-IPHNDAQLY 175

[Close]

BLAST of Cucsat.G2498 vs. NCBI nr
Match: KAA0052608.1 (uncharacterized protein E6C27_scaffold120G002160 [Cucumis melo var. makuwa] >TYK13219.1 uncharacterized protein E5676_scaffold255G008340 [Cucumis melo var. makuwa])

HSP 1 Score: 223 bits (569), Expect = 1.62e-72
Identity = 113/116 (97.41%), Postives = 114/116 (98.28%), Query Frame = 0


Query: 1   MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 60
           MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS
Sbjct: 61  MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 120

Query: 61  CTECFCMEATAVAEDHHQLLNLSDITEAINVAIDPKLLAPNQHHNDSIPHNDAQLY 116
           CTECFCMEA AVAEDHHQLLNLSDIT+AINVAIDPKLLAPNQHHND IPHNDAQLY
Sbjct: 121 CTECFCMEAIAVAEDHHQLLNLSDITDAINVAIDPKLLAPNQHHND-IPHNDAQLY 175

[Close]

BLAST of Cucsat.G2498 vs. NCBI nr
Match: XP_038893157.1 (uncharacterized protein LOC120082020 [Benincasa hispida])

HSP 1 Score: 192 bits (488), Expect = 3.27e-60
Identity = 101/115 (87.83%), Postives = 107/115 (93.04%), Query Frame = 0


Query: 1   MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 60
           MKREYLNSIKQFHS KEVKVEKNGEEF+VKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS
Sbjct: 61  MKREYLNSIKQFHSPKEVKVEKNGEEFKVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 120

Query: 61  CTECFCMEATAVAEDHHQLLNLSDITEAINVAIDPKLLAPNQHHNDSIPHNDAQL 115
           CTECFCMEA AVAE+H +LLN+SDITEAINVAID KLLA NQHH D IP NDA++
Sbjct: 121 CTECFCMEAIAVAENH-RLLNVSDITEAINVAIDGKLLAGNQHHKD-IPENDAEI 173

[Close]

BLAST of Cucsat.G2498 vs. NCBI nr
Match: KAG6581368.1 (hypothetical protein SDJN03_21370, partial [Cucurbita argyrosperma subsp. sororia])

HSP 1 Score: 154 bits (389), Expect = 1.72e-45
Identity = 82/115 (71.30%), Postives = 95/115 (82.61%), Query Frame = 0


Query: 1   MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 60
           MKREYLNS+KQ H+ KEVKVEK GEE RVKVRCEKGGDRLV+VLEAF+KMGLNV++A+VS
Sbjct: 36  MKREYLNSVKQIHAPKEVKVEKVGEELRVKVRCEKGGDRLVTVLEAFDKMGLNVLQAKVS 95

Query: 61  CTECFCMEATAVAEDHHQLLNLSDITEAINVAIDPKLLAPNQHHNDSIPHNDAQL 115
           C+ECF MEA AVAED  Q LN+SDITEAIN AID K LA NQ   ++ P  D ++
Sbjct: 96  CSECFSMEAIAVAEDE-QSLNISDITEAINAAIDGKSLAANQQQKET-PEKDDEI 148

[Close]

BLAST of Cucsat.G2498 vs. ExPASy TrEMBL
Match: A0A0A0KHW9 (Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_6G519710 PE=4 SV=1)

HSP 1 Score: 233 bits (594), Expect = 1.26e-76
Identity = 116/116 (100.00%), Postives = 116/116 (100.00%), Query Frame = 0


Query: 1   MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 60
           MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS
Sbjct: 61  MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 120

Query: 61  CTECFCMEATAVAEDHHQLLNLSDITEAINVAIDPKLLAPNQHHNDSIPHNDAQLY 116
           CTECFCMEATAVAEDHHQLLNLSDITEAINVAIDPKLLAPNQHHNDSIPHNDAQLY
Sbjct: 121 CTECFCMEATAVAEDHHQLLNLSDITEAINVAIDPKLLAPNQHHNDSIPHNDAQLY 176

[Close]

BLAST of Cucsat.G2498 vs. ExPASy TrEMBL
Match: A0A5A7UBN8 (Uncharacterized protein OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold255G008340 PE=4 SV=1)

HSP 1 Score: 223 bits (569), Expect = 7.83e-73
Identity = 113/116 (97.41%), Postives = 114/116 (98.28%), Query Frame = 0


Query: 1   MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 60
           MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS
Sbjct: 61  MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 120

Query: 61  CTECFCMEATAVAEDHHQLLNLSDITEAINVAIDPKLLAPNQHHNDSIPHNDAQLY 116
           CTECFCMEA AVAEDHHQLLNLSDIT+AINVAIDPKLLAPNQHHND IPHNDAQLY
Sbjct: 121 CTECFCMEAIAVAEDHHQLLNLSDITDAINVAIDPKLLAPNQHHND-IPHNDAQLY 175

[Close]

BLAST of Cucsat.G2498 vs. ExPASy TrEMBL
Match: E5GC31 (Uncharacterized protein OS=Cucumis melo subsp. melo OX=412675 PE=4 SV=1)

HSP 1 Score: 223 bits (569), Expect = 7.83e-73
Identity = 113/116 (97.41%), Postives = 114/116 (98.28%), Query Frame = 0


Query: 1   MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 60
           MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS
Sbjct: 61  MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 120

Query: 61  CTECFCMEATAVAEDHHQLLNLSDITEAINVAIDPKLLAPNQHHNDSIPHNDAQLY 116
           CTECFCMEA AVAEDHHQLLNLSDIT+AINVAIDPKLLAPNQHHND IPHNDAQLY
Sbjct: 121 CTECFCMEAIAVAEDHHQLLNLSDITDAINVAIDPKLLAPNQHHND-IPHNDAQLY 175

[Close]

BLAST of Cucsat.G2498 vs. ExPASy TrEMBL
Match: A0A1S3B049 (uncharacterized protein LOC103484437 OS=Cucumis melo OX=3656 GN=LOC103484437 PE=4 SV=1)

HSP 1 Score: 223 bits (569), Expect = 7.83e-73
Identity = 113/116 (97.41%), Postives = 114/116 (98.28%), Query Frame = 0


Query: 1   MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 60
           MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS
Sbjct: 61  MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 120

Query: 61  CTECFCMEATAVAEDHHQLLNLSDITEAINVAIDPKLLAPNQHHNDSIPHNDAQLY 116
           CTECFCMEA AVAEDHHQLLNLSDIT+AINVAIDPKLLAPNQHHND IPHNDAQLY
Sbjct: 121 CTECFCMEAIAVAEDHHQLLNLSDITDAINVAIDPKLLAPNQHHND-IPHNDAQLY 175

[Close]

BLAST of Cucsat.G2498 vs. ExPASy TrEMBL
Match: A0A6J1IR65 (uncharacterized protein LOC111478631 OS=Cucurbita maxima OX=3661 GN=LOC111478631 PE=4 SV=1)

HSP 1 Score: 154 bits (390), Expect = 1.26e-45
Identity = 82/115 (71.30%), Postives = 95/115 (82.61%), Query Frame = 0


Query: 1   MKREYLNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVEARVS 60
           MKREYLNS+KQ H+ KEVKVEK GEEFRVKVRCEKGGDRLV+VLEAF+KMGLNV++A+VS
Sbjct: 61  MKREYLNSVKQIHAPKEVKVEKVGEEFRVKVRCEKGGDRLVTVLEAFDKMGLNVLQAKVS 120

Query: 61  CTECFCMEATAVAEDHHQLLNLSDITEAINVAIDPKLLAPNQHHNDSIPHNDAQL 115
           C+ECF MEA AVAED  Q LN+ DITEAIN AID K LA NQ   ++ P  D ++
Sbjct: 121 CSECFSMEAIAVAEDE-QSLNICDITEAINAAIDGKSLAANQQQKET-PEKDDEI 173

[Close]

BLAST of Cucsat.G2498 vs. TAIR 10
Match: AT1G29270.1 (unknown protein; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT2G40435.1); Has 98 Blast hits to 98 proteins in 15 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 98; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink). )

HSP 1 Score: 78.6 bits (192), Expect = 3.8e-15
Identity = 40/97 (41.24%), Postives = 63/97 (64.95%), Query Frame = 0


Query: 1   MKREY----LNSIKQFHSSKEVKVEKNGEEFRVKVRCEKGGDRLVSVLEAFEKMGLNVVE 60
           ++REY    +   +  H  +EVKVEK GE F+VK++  +G + LV++LEAFE+MGLNV +
Sbjct: 52  LQREYEDLKITKKESLHQFQEVKVEKIGEMFQVKIKSPRGENNLVNILEAFEEMGLNVAQ 111

Query: 61  ARVSCTECFCMEATAVAEDHHQLLNLSDITEAINVAI 94
           AR SC + F MEA    +   +L ++ D+T+ +  A+
Sbjct: 112 ARASCLDSFAMEAIVAPQSKDKLCSVDDLTQTLVKAL 148

[Close]

BLAST of Cucsat.G2498 vs. TAIR 10
Match: AT2G40435.1 (BEST Arabidopsis thaliana protein match is: transcription regulators (TAIR:AT3G56220.1); Has 289 Blast hits to 289 proteins in 30 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 289; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink). )

HSP 1 Score: 48.9 bits (115), Expect = 3.2e-06
Identity = 30/77 (38.96%), Postives = 44/77 (57.14%), Query Frame = 0


Query: 18  VKVEKNGEEFRVKVRCEKG-GDRLVSVLEAFEKMGLNVVEARVSCTECFCMEATAVAEDH 77
           V VE   + F + V   K     LVSVLEAFE +GLNV+EAR SCT+ F + A  +  + 
Sbjct: 71  VTVETLDKGFMINVFSGKNQPGMLVSVLEAFEDIGLNVLEARASCTDSFSLHAMGLENED 130

Query: 78  HQLLNLSDITEAINVAI 94
            + ++   + +A+  AI
Sbjct: 131 GENMDAEAVKQAVTDAI 147

[Close]

BLAST of Cucsat.G2498 vs. TAIR 10
Match: AT3G56220.1 (transcription regulators )

HSP 1 Score: 46.6 bits (109), Expect = 1.6e-05
Identity = 31/78 (39.74%), Postives = 43/78 (55.13%), Query Frame = 0


Query: 18  VKVEKNGEEFRVKVRCEKG-GDRLVSVLEAFEKMGLNVVEARVSCTECFCMEATAVA-ED 77
           V VE   + F +KV   K     LV VLE FE +GL+VVEARVSCT+ F + A   +  D
Sbjct: 71  VTVETLEKGFMIKVMSRKNEAGMLVCVLETFEDLGLDVVEARVSCTDTFSLHAIGSSNND 130

Query: 78  HHQLLNLSDITEAINVAI 94
               ++   + +A+  AI
Sbjct: 131 DGDCIDAEAVKQAVAEAI 148

The following BLAST results are available for this feature:

BLAST of Cucsat.G2498 vs.


Match Name	E-value	Identity	Description

BLAST of Cucsat.G2498 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_004134653.1	2.60e-76	100.00	uncharacterized protein LOC101213083 [Cucumis sativus] >KGN49320.1 hypothetical ...	[more]
XP_008439723.1	1.62e-72	97.41	PREDICTED: uncharacterized protein LOC103484437 [Cucumis melo] >ADN34030.1 hypot...	[more]
KAA0052608.1	1.62e-72	97.41	uncharacterized protein E6C27_scaffold120G002160 [Cucumis melo var. makuwa] >TYK...	[more]
XP_038893157.1	3.27e-60	87.83	uncharacterized protein LOC120082020 [Benincasa hispida]	[more]
KAG6581368.1	1.72e-45	71.30	hypothetical protein SDJN03_21370, partial [Cucurbita argyrosperma subsp. sorori...	[more]

BLAST of Cucsat.G2498 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A0A0KHW9	1.26e-76	100.00	Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_6G519710 PE=4 SV=1	[more]
A0A5A7UBN8	7.83e-73	97.41	Uncharacterized protein OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold...	[more]
E5GC31	7.83e-73	97.41	Uncharacterized protein OS=Cucumis melo subsp. melo OX=412675 PE=4 SV=1	[more]
A0A1S3B049	7.83e-73	97.41	uncharacterized protein LOC103484437 OS=Cucumis melo OX=3656 GN=LOC103484437 PE=...	[more]
A0A6J1IR65	1.26e-45	71.30	uncharacterized protein LOC111478631 OS=Cucurbita maxima OX=3661 GN=LOC111478631...	[more]

BLAST of Cucsat.G2498 vs. TAIR 10


Match Name	E-value	Identity	Description
AT1G29270.1	3.8e-15	41.24	unknown protein; BEST Arabidopsis thaliana protein match is: unknown protein (TA...	[more]
AT2G40435.1	3.2e-06	38.96	BEST Arabidopsis thaliana protein match is: transcription regulators (TAIR:AT3G5...	[more]
AT3G56220.1	1.6e-05	39.74	transcription regulators	[more]

InterPro

Analysis Name: InterPro Annotations of Cucumber (B10) v3
Date Performed: 2021-10-25


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 41..68
None	No IPR available	PANTHER	PTHR31945:SF27	TRANSCRIPTION FACTOR BHLH35-LIKE PROTEIN	coord: 1..156
None	No IPR available	PANTHER	PTHR31945	TRANSCRIPTION FACTOR SCREAM2-RELATED	coord: 1..156

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
Cucsat.G2498.T1	Cucsat.G2498.T1	mRNA
Cucsat.G2498.T3	Cucsat.G2498.T3	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006355	regulation of transcription, DNA-templated
cellular_component	GO:0005634	nucleus
molecular_function	GO:0003700	DNA-binding transcription factor activity
molecular_function	GO:0043565	sequence-specific DNA binding