CsGy2G015760 (gene) Cucumber (Gy14) v2.1

Overview
NameCsGy2G015760
Typegene
OrganismCucumis sativus L. var. sativus cv. Gy14 (Cucumber (Gy14) v2.1)
DescriptionGamma-secretase subunit PEN-2
LocationGy14Chr2: 15616923 .. 15620916 (+)
RNA-Seq ExpressionCsGy2G015760
SyntenyCsGy2G015760
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: five_prime_UTRexonCDSpolypeptidethree_prime_UTR
Hold the cursor over a type above to highlight its positions in the sequence below.
TGAAAAAATAAATTTTGAAGCGAAGTAAAATTGAGTAAAAGAGAAAACGAGGAAGGAACGATTTCTCATTCGAACTCCTCTCGCAATGGAGACCTTGCAGAATCCAAACGCAAACACCAATTCCAATCCAAATACCATATCTTCCCCAATTCGTGTGTTATGGCCTACCATCGATGGCTCTCTGGGTTTGTCGGAGGAAGAATCGGTGAGCTATGCTCGTAGGTTCTACAAATTTGGATTTGCATTGCTTCCATTTCTTTGGGCGGTTAATTGCTTCTACTTCTGGCCTGTTCTTCGATCCCGCTCGTTTCCTCGCATCCGACCCTGTGAGTTTTCCTCTCTTAACTTCTACTTTCAATTATTTCTGAAATTTTCACACTCATTGCTGTTCAAAGAAAAATATGATTAGGATCCTATTGTTGGATTTATCATACCTCAATATTCATGAGCATCAACAATTATATTTTAACTTCATTTTGCTTCACTGGTTATGTTTTAATGTGTGGTAGGCAATAACTCAAATTATTTTGTACAGAAATACATGACGCTATTGTAATGTAGATATTTGTGTTAGAAAACCCGACGCCCATCGGTCAATCCTTGTTCATCTGTTGTTTTTTCCGTAGGCTTGGTTTGTAAATACTAAGCCTGTTTGTTTGTGCAAATATCCTACCTTTTTAATTATTCCTTCTCATTGTTGTTTGCTTGGTCGTGGCGACTACATTATTGTTTTGAGTTTGATAGCTTTTATAATAATACTTTAAGGATGATACCTTGGTACTTCTCATAATTTGATGAATTAAATGGATAGAAGATCAGTAATCGTGTTCAAATTCAATAAATTGAGCCTTAAGAATTTGTTGTTCTTTTCCTTATGCTTGGTCGGTAGATACTAGAAGTTCTAACCTGTTTATTTGTGCAAATACCCTGACTGTTTTATGTTCTACAAAGGACAGACATATATAGATTGGGTACATCAAATGGGGATTGGAGGAATTTGAACCTTTGATCCCAAGTAAGGTAGCACACTCTAATTACTATTGGTCTAGGCTCACTTTAGTCAAAGTGCTAATGCTTTTGAAGGAAGGTAAAATTTATTGGCTCTTACGCTCCAAGTATCACATTTGTAAATAAGCTTTTGATTGTTTGTTGAAGTTGTAGTTCAATTGAGCTTTATTATGCATATCCCGTCTTCTTATGATTCTTTTTGTGAAAATTTTGGTCAAGATTCTTGCATGTTGTCTGCCAAGTATGCAGCAATTTAAACTTTTGGCCTCAGATTATTTGTCATAGTAGTTGGTCCTTTCAACTTCATTTGGCATATCCTCTTTTTGGGAATTATGCGTGTGAACTTTGTTATGCATTTATTTTATGCACCTCGAGCTGTGTATACACGTCTATATGTACAAATTTAATCATAAACCAACTAGGAAAATTAGGATGGTTATGTATATAAGAAGGTTGGGTCTTGTGTGTTTGCATGCATATGGACGAGAAATGCTCAAAGGGGGACATTCCATGGTTGTTTACTATACATTGAATGCATTATCTCTATCTTTACGTATCTTCTTCGTCGTATGAGTATTGATTGTTTGGAGTGGAGATACTCTCCAAAACCCGTGGTTCAAGCCCACGGAAAATAGGAGTGGCTTGGTTTTGTGTGTTGTTGCTAATTTAGTTAATAAGGGTGGCCTATCTTGAATTGCATGCGTATATATCAATGAATTTGATTCAAAAATGAAGGTTGGTCGGTTGTCTTTTTTTGATAAGTGTATAATAGGGGTGATTAAACTTAGTTATTATGTACTTGTTCTTACCATTCAATTGAAACATCCATGCTAGCTACACAGAACCTTGTTAGTAATAATTAATAAGTAAAATTGTTTTATAGTTTTATTTATAGTTTACTTTAACAACGACTACTATAATTTTAATATAACAATGAATTTATTTGAGATGAATAGTGTGTATGCTTCAAAGCTTTTCAGTCGGTCATTCTGATAAGATCAATAATTCTGAGGATACTCCTTTTCCAAGACCATTAATCATTGGTAACACAAATAGAATTCTATATTTATTTGCAAAAAAATCGTAGAAGTTCCACATGTTTTATAAAGATGAGTTGTTTCTTTGGGTTTGTTTATTATGAAAAGTTTGACACTAGATAAAATCCAGAATTTTGTATCATCTCTCTCTGAATGGCTATCCCATGAAATTTTTAGGATGAGATCGCGTCCATAGTATCAATGAGGAGACGGTACTGAGGACTCGTTCGTTCAAATGCTATAATAGGTTACAACTTCTGAAGGAAGTCAGTCAACATATTTTCAGTCATAACTTCTCGATCTTTAGTCAAGAGTACCGAAGAATTAATGAGGGTATAACTGGGCCCAGGAGTGAAGTTGAGGACTTACGAGTTTCTGTCTTCCTACCTTTTATGGATGGTGTTCCTTACATACAGATATTATGATTGATTCTCATCTTTTATTCAAATAACTTATGGTCTTTTCATTTTTTTTGTAATCTCCTTGATTTTTTTGGGAGATGGTCAGATATCTTGTCAAGTTCCCATAACTTTAGGCTATCATAATTCTTTCCTGGAAATTTTGGGTATGTATTTCTGTTTATAGTTATTCCTAGAACCAGGTGTGGTAGAATATTAATTTTTATTTAATAGACATTTACTTGAGCTGTTTTTCACATTAACTACTTTTAGGGTCAGTCCAATTACCTAACAATTTGAAATTGTTGTTTCTTTAGATATTGTTGGCTCAGCTATCGGCTTTGGTGTTTTCATGGCCATTATTTCGTCTTGGGCATTAACATTTTCCATTGGAGGAGAACGCCTGTTTGGACCTGTTTGGGATAAACTAGTGATGTACAATCTTGCTGACAAAGTAGGATTAACAGGTTGGAGCTAGTCTGGTTCCCTCCCTTCGGCAACCAACTTCAACCTTCTTCTATATTTCAAAATTTGTAACTCTTGACGGTCATTGTTTTCTTGAAAGATCAAAGTTGAAGCTTTTGGTTTCCCTTCTTCAAGTGCTCCAATTGTCGAACATGAACATTTGCATTACCCATGTTGATTCATGTTAATAGTTGATGCACAAGTTTGAACCGGGTCTCCCTTCAACTGCGAACTAAGATTTGTGGATAAAAATCTAAACCGGTTCTCTTGAATTCTTCTTTGCTTTCTTTTTGTCCCACTTTCAATACTATAAGTCGTGCTCTTTTCTGGTTCCCCTACTTCAGAACATCCATTTTGAAGGTGGAATACATCTGGAAGCAAGTTAGAAACTCCCTTAAAATTCTTAGGGGATGGTAGTGTACAGTGATCAACAATCCCCAAAAGAAAGGTATGATTATTGTATACTGTAGCACTCCTTGTTATGGATATATTAGGATAACTAGTACGGTTGGTAAAAGCGTATTTTAGTAAATATAGTTTTCTTTAGAACTTTTAGTTATAAATTAGAGGGAGTGTGGTTGAGAGAATTTTTCTGTGGGATTTTCTATCGAGAGGGCTATTAGGGAGAGGCTGGCTCTCTTGAAAGGCTAGATTATCTTGTTACTCTTCCTATTGATATTACAACAAATTTTCATATATTTCTATCATAGTGTTCATGGTTGGTTTAGTTGTTCTTGAGTATTCTTGTTAAGGAGTATCTTAAAAAATACCTCTACGATGGGACAGTTGGGAGATTATGTGTATATATATAGTTCTTAAGGATATTATTGTATTCCCAATTTGAGACATGTGCCATAGTTGATGGATTGGATCAGATAGCATTGAAACAAGTTTGTTTTCAAATGCTAGTTTTGGATAATTGCCTCCATCAGATTAATCTGGGATTCACTTAATTAACTTCGGTTAGTAGAAATGCTAACCTCTTGACATTTTTGTGGTGTTATCAATATCCAAATGGGAAAGCTAATCCCTAAAATAGAAAAAGAGGGAACCAAAAAACTTGCCAGAAATAGGGAAGGATGGTGG

mRNA sequence

TGAAAAAATAAATTTTGAAGCGAAGTAAAATTGAGTAAAAGAGAAAACGAGGAAGGAACGATTTCTCATTCGAACTCCTCTCGCAATGGAGACCTTGCAGAATCCAAACGCAAACACCAATTCCAATCCAAATACCATATCTTCCCCAATTCGTGTGTTATGGCCTACCATCGATGGCTCTCTGGGTTTGTCGGAGGAAGAATCGGTGAGCTATGCTCGTAGGTTCTACAAATTTGGATTTGCATTGCTTCCATTTCTTTGGGCGGTTAATTGCTTCTACTTCTGGCCTGTTCTTCGATCCCGCTCGTTTCCTCGCATCCGACCCTATATTGTTGGCTCAGCTATCGGCTTTGGTGTTTTCATGGCCATTATTTCGTCTTGGGCATTAACATTTTCCATTGGAGGAGAACGCCTGTTTGGACCTGTTTGGGATAAACTAGTGATGTACAATCTTGCTGACAAAGTAGGATTAACAGGTTGGAGCTAGTCTGGTTCCCTCCCTTCGGCAACCAACTTCAACCTTCTTCTATATTTCAAAATTTGTAACTCTTGACGGTCATTGTTTTCTTGAAAGATCAAAGTTGAAGCTTTTGGTTTCCCTTCTTCAAGTGCTCCAATTGTCGAACATGAACATTTGCATTACCCATGTTGATTCATGTTAATAGTTGATGCACAAGTTTGAACCGGGTCTCCCTTCAACTGCGAACTAAGATTTGTGGATAAAAATCTAAACCGGTTCTCTTGAATTCTTCTTTGCTTTCTTTTTGTCCCACTTTCAATACTATAAGTCGTGCTCTTTTCTGGTTCCCCTACTTCAGAACATCCATTTTGAAGGTGGAATACATCTGGAAGCAAGTTAGAAACTCCCTTAAAATTCTTAGGGGATGGTAGTGTACAGTGATCAACAATCCCCAAAAGAAAGGTATGATTATTGTATACTGTAGCACTCCTTGTTATGGATATATTAGGATAACTAGTACGGTTGGTAAAAGCGTATTTTAGTAAATATAGTTTTCTTTAGAACTTTTAGTTATAAATTAGAGGGAGTGTGGTTGAGAGAATTTTTCTGTGGGATTTTCTATCGAGAGGGCTATTAGGGAGAGGCTGGCTCTCTTGAAAGGCTAGATTATCTTGTTACTCTTCCTATTGATATTACAACAAATTTTCATATATTTCTATCATAGTGTTCATGGTTGGTTTAGTTGTTCTTGAGTATTCTTGTTAAGGAGTATCTTAAAAAATACCTCTACGATGGGACAGTTGGGAGATTATGTGTATATATATAGTTCTTAAGGATATTATTGTATTCCCAATTTGAGACATGTGCCATAGTTGATGGATTGGATCAGATAGCATTGAAACAAGTTTGTTTTCAAATGCTAGTTTTGGATAATTGCCTCCATCAGATTAATCTGGGATTCACTTAATTAACTTCGGTTAGTAGAAATGCTAACCTCTTGACATTTTTGTGGTGTTATCAATATCCAAATGGGAAAGCTAATCCCTAAAATAGAAAAAGAGGGAACCAAAAAACTTGCCAGAAATAGGGAAGGATGGTGG

Coding sequence (CDS)

ATGGAGACCTTGCAGAATCCAAACGCAAACACCAATTCCAATCCAAATACCATATCTTCCCCAATTCGTGTGTTATGGCCTACCATCGATGGCTCTCTGGGTTTGTCGGAGGAAGAATCGGTGAGCTATGCTCGTAGGTTCTACAAATTTGGATTTGCATTGCTTCCATTTCTTTGGGCGGTTAATTGCTTCTACTTCTGGCCTGTTCTTCGATCCCGCTCGTTTCCTCGCATCCGACCCTATATTGTTGGCTCAGCTATCGGCTTTGGTGTTTTCATGGCCATTATTTCGTCTTGGGCATTAACATTTTCCATTGGAGGAGAACGCCTGTTTGGACCTGTTTGGGATAAACTAGTGATGTACAATCTTGCTGACAAAGTAGGATTAACAGGTTGGAGCTAG

Protein sequence

METLQNPNANTNSNPNTISSPIRVLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWAVNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPVWDKLVMYNLADKVGLTGWS*
Homology
BLAST of CsGy2G015760 vs. ExPASy Swiss-Prot
Match: Q9FY84 (Probable gamma-secretase subunit PEN-2 OS=Arabidopsis thaliana OX=3702 GN=At5g09310 PE=2 SV=1)

HSP 1 Score: 193.4 bits (490), Expect = 1.7e-48
Identity = 92/134 (68.66%), Postives = 113/134 (84.33%), Query Frame = 0

Query: 1   METLQNPNANTNSNPNTISSPI--RVLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFL 60
           +  ++N N N N NPN +S+ I    +WPTIDG LGL+EE SV YARRFYKFGFALLP+L
Sbjct: 11  LNPIRNRNPNPNPNPNPLSTIISSAQVWPTIDGPLGLTEEASVDYARRFYKFGFALLPWL 70

Query: 61  WAVNCFYFWPVLR-SRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPVWDK 120
           W VNCFYFWPVLR SR+FP+IR Y+V SAIGF VF A++S+WALTFSIGGE+LFGP++DK
Sbjct: 71  WFVNCFYFWPVLRHSRAFPQIRNYVVRSAIGFSVFTALLSAWALTFSIGGEQLFGPLYDK 130

Query: 121 LVMYNLADKVGLTG 132
           LVMYN+AD++GL+G
Sbjct: 131 LVMYNVADRLGLSG 144

BLAST of CsGy2G015760 vs. ExPASy Swiss-Prot
Match: Q5G235 (Gamma-secretase subunit PEN-2 OS=Bos taurus OX=9913 GN=PSENEN PE=3 SV=1)

HSP 1 Score: 59.3 bits (142), Expect = 3.8e-08
Identity = 33/93 (35.48%), Postives = 52/93 (55.91%), Query Frame = 0

Query: 35  LSEEESVSYARRFYKFGFALLPFLWAVNCFYFW------PVLRSRSFPRIRPYIVGSAIG 94
           +S EE ++  R++Y  GFA LPFLW VN F+F+      P    +S  +I+ Y+  SA+G
Sbjct: 6   VSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFREAFIVPAYTEQS--QIKGYVWRSAVG 65

Query: 95  FGVFMAIISSWALTFSIGGERLFGPVWDKLVMY 122
           F +++ ++S+W   F I     + P W  L  Y
Sbjct: 66  FFLWVIVLSTWITIFQI-----YRPRWGALGDY 91

BLAST of CsGy2G015760 vs. ExPASy Swiss-Prot
Match: Q9NZ42 (Gamma-secretase subunit PEN-2 OS=Homo sapiens OX=9606 GN=PSENEN PE=1 SV=1)

HSP 1 Score: 58.2 bits (139), Expect = 8.5e-08
Identity = 33/93 (35.48%), Postives = 51/93 (54.84%), Query Frame = 0

Query: 35  LSEEESVSYARRFYKFGFALLPFLWAVNCFYFW------PVLRSRSFPRIRPYIVGSAIG 94
           +S EE ++  R++Y  GFA LPFLW VN F+F+      P    +S  +I+ Y+  SA+G
Sbjct: 6   VSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFREAFLVPAYTEQS--QIKGYVWRSAVG 65

Query: 95  FGVFMAIISSWALTFSIGGERLFGPVWDKLVMY 122
           F  ++ +++SW   F I     + P W  L  Y
Sbjct: 66  FLFWVIVLTSWITIFQI-----YRPRWGALGDY 91

BLAST of CsGy2G015760 vs. ExPASy Swiss-Prot
Match: Q9CQR7 (Gamma-secretase subunit PEN-2 OS=Mus musculus OX=10090 GN=Psenen PE=1 SV=1)

HSP 1 Score: 57.4 bits (137), Expect = 1.5e-07
Identity = 33/93 (35.48%), Postives = 51/93 (54.84%), Query Frame = 0

Query: 35  LSEEESVSYARRFYKFGFALLPFLWAVNCFYFW------PVLRSRSFPRIRPYIVGSAIG 94
           +S EE ++  R++Y  GFA LPFLW VN F+F+      P    +S  +I+ Y+  SA+G
Sbjct: 6   VSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFREAFLAPAYTEQS--QIKGYVWRSAVG 65

Query: 95  FGVFMAIISSWALTFSIGGERLFGPVWDKLVMY 122
           F  ++ I+++W   F I     + P W  L  Y
Sbjct: 66  FLFWVIILATWITIFQI-----YRPRWGALGDY 91

BLAST of CsGy2G015760 vs. ExPASy Swiss-Prot
Match: Q6QI68 (Gamma-secretase subunit PEN-2 OS=Rattus norvegicus OX=10116 GN=Psenen PE=3 SV=1)

HSP 1 Score: 57.0 bits (136), Expect = 1.9e-07
Identity = 32/93 (34.41%), Postives = 51/93 (54.84%), Query Frame = 0

Query: 35  LSEEESVSYARRFYKFGFALLPFLWAVNCFYFW------PVLRSRSFPRIRPYIVGSAIG 94
           +S EE ++  R++Y  GFA LPFLW VN F+F+      P    +S  +I+ Y+  SA+G
Sbjct: 6   VSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFKEAFFAPAYTEQS--QIKGYVWRSAVG 65

Query: 95  FGVFMAIISSWALTFSIGGERLFGPVWDKLVMY 122
           F  ++ ++++W   F I     + P W  L  Y
Sbjct: 66  FLFWVIVLTTWITIFQI-----YRPRWGALGDY 91

BLAST of CsGy2G015760 vs. NCBI nr
Match: XP_011649406.1 (probable gamma-secretase subunit PEN-2 [Cucumis sativus] >KGN62163.1 hypothetical protein Csa_006741 [Cucumis sativus])

HSP 1 Score: 280 bits (717), Expect = 2.25e-95
Identity = 133/133 (100.00%), Postives = 133/133 (100.00%), Query Frame = 0

Query: 1   METLQNPNANTNSNPNTISSPIRVLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWA 60
           METLQNPNANTNSNPNTISSPIRVLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWA
Sbjct: 1   METLQNPNANTNSNPNTISSPIRVLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWA 60

Query: 61  VNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPVWDKLVM 120
           VNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPVWDKLVM
Sbjct: 61  VNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPVWDKLVM 120

Query: 121 YNLADKVGLTGWS 133
           YNLADKVGLTGWS
Sbjct: 121 YNLADKVGLTGWS 133

BLAST of CsGy2G015760 vs. NCBI nr
Match: KAA0040759.1 (putative gamma-secretase subunit PEN-2 [Cucumis melo var. makuwa] >TYK02074.1 putative gamma-secretase subunit PEN-2 [Cucumis melo var. makuwa])

HSP 1 Score: 268 bits (685), Expect = 1.71e-90
Identity = 127/133 (95.49%), Postives = 129/133 (96.99%), Query Frame = 0

Query: 1   METLQNPNANTNSNPNTISSPIRVLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWA 60
           MET  NPNANTNSNPNTI+SPI VLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWA
Sbjct: 1   METSHNPNANTNSNPNTITSPIPVLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWA 60

Query: 61  VNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPVWDKLVM 120
           VNCFYFWPVLRSRSFPRIRPYIVGSAIGFGV MAIISSWALTFSIGGERLFGPVWDKLVM
Sbjct: 61  VNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVSMAIISSWALTFSIGGERLFGPVWDKLVM 120

Query: 121 YNLADKVGLTGWS 133
           YNLADK+GLTGWS
Sbjct: 121 YNLADKLGLTGWS 133

BLAST of CsGy2G015760 vs. NCBI nr
Match: XP_038900346.1 (probable gamma-secretase subunit PEN-2 [Benincasa hispida])

HSP 1 Score: 258 bits (659), Expect = 3.22e-86
Identity = 124/139 (89.21%), Postives = 128/139 (92.09%), Query Frame = 0

Query: 1   METLQNPNANTNSNPNT------ISSPIRVLWPTIDGSLGLSEEESVSYARRFYKFGFAL 60
           ME+ QNPN NTNSNPN       +SSPI VLWPTIDGSLGLSEEESVSYARRFYKFGFAL
Sbjct: 16  MESSQNPNTNTNSNPNPNRIQNPVSSPIAVLWPTIDGSLGLSEEESVSYARRFYKFGFAL 75

Query: 61  LPFLWAVNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPV 120
           LPFLWAVNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFG V
Sbjct: 76  LPFLWAVNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGTV 135

Query: 121 WDKLVMYNLADKVGLTGWS 133
           WDKLVMYNLAD++GLTGWS
Sbjct: 136 WDKLVMYNLADRLGLTGWS 154

BLAST of CsGy2G015760 vs. NCBI nr
Match: XP_022971629.1 (probable gamma-secretase subunit PEN-2 [Cucurbita maxima])

HSP 1 Score: 252 bits (644), Expect = 3.51e-84
Identity = 121/137 (88.32%), Postives = 125/137 (91.24%), Query Frame = 0

Query: 1   METLQNPNANTNSNP----NTISSPIRVLWPTIDGSLGLSEEESVSYARRFYKFGFALLP 60
           ME  QN N+N N NP    N +SSPI VLWPTIDGSLGLSEEESVSYARRFYKFGFALLP
Sbjct: 1   MENSQNSNSNLNPNPIRIQNLVSSPIAVLWPTIDGSLGLSEEESVSYARRFYKFGFALLP 60

Query: 61  FLWAVNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPVWD 120
           FLWAVNCFYFWPVLRSRSFPRIRPYIVGSAIGF VFMAIISSWALTF+IGGERLFGPVWD
Sbjct: 61  FLWAVNCFYFWPVLRSRSFPRIRPYIVGSAIGFAVFMAIISSWALTFAIGGERLFGPVWD 120

Query: 121 KLVMYNLADKVGLTGWS 133
           KLVMYNLADK+GLTGWS
Sbjct: 121 KLVMYNLADKLGLTGWS 137

BLAST of CsGy2G015760 vs. NCBI nr
Match: XP_022931973.1 (probable gamma-secretase subunit PEN-2 [Cucurbita moschata])

HSP 1 Score: 250 bits (639), Expect = 2.03e-83
Identity = 120/137 (87.59%), Postives = 124/137 (90.51%), Query Frame = 0

Query: 1   METLQNPNANTNSNP----NTISSPIRVLWPTIDGSLGLSEEESVSYARRFYKFGFALLP 60
           ME  QN N+N N NP    N +SSPI VLWPTIDGSLGLSEEESVSYARRFYKFGFALLP
Sbjct: 1   MENSQNSNSNPNPNPIRIQNLVSSPIAVLWPTIDGSLGLSEEESVSYARRFYKFGFALLP 60

Query: 61  FLWAVNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPVWD 120
           FLWAVNCFYFWPVLRS SFPRIRPYIVGSAIGF VFMAIISSWALTF+IGGERLFGPVWD
Sbjct: 61  FLWAVNCFYFWPVLRSHSFPRIRPYIVGSAIGFAVFMAIISSWALTFAIGGERLFGPVWD 120

Query: 121 KLVMYNLADKVGLTGWS 133
           KLVMYNLADK+GLTGWS
Sbjct: 121 KLVMYNLADKLGLTGWS 137

BLAST of CsGy2G015760 vs. ExPASy TrEMBL
Match: A0A0A0LK38 (Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_2G302290 PE=3 SV=1)

HSP 1 Score: 280 bits (717), Expect = 1.09e-95
Identity = 133/133 (100.00%), Postives = 133/133 (100.00%), Query Frame = 0

Query: 1   METLQNPNANTNSNPNTISSPIRVLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWA 60
           METLQNPNANTNSNPNTISSPIRVLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWA
Sbjct: 1   METLQNPNANTNSNPNTISSPIRVLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWA 60

Query: 61  VNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPVWDKLVM 120
           VNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPVWDKLVM
Sbjct: 61  VNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPVWDKLVM 120

Query: 121 YNLADKVGLTGWS 133
           YNLADKVGLTGWS
Sbjct: 121 YNLADKVGLTGWS 133

BLAST of CsGy2G015760 vs. ExPASy TrEMBL
Match: A0A5A7THJ9 (Putative gamma-secretase subunit PEN-2 OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold680G00610 PE=3 SV=1)

HSP 1 Score: 268 bits (685), Expect = 8.30e-91
Identity = 127/133 (95.49%), Postives = 129/133 (96.99%), Query Frame = 0

Query: 1   METLQNPNANTNSNPNTISSPIRVLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWA 60
           MET  NPNANTNSNPNTI+SPI VLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWA
Sbjct: 1   METSHNPNANTNSNPNTITSPIPVLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWA 60

Query: 61  VNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPVWDKLVM 120
           VNCFYFWPVLRSRSFPRIRPYIVGSAIGFGV MAIISSWALTFSIGGERLFGPVWDKLVM
Sbjct: 61  VNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVSMAIISSWALTFSIGGERLFGPVWDKLVM 120

Query: 121 YNLADKVGLTGWS 133
           YNLADK+GLTGWS
Sbjct: 121 YNLADKLGLTGWS 133

BLAST of CsGy2G015760 vs. ExPASy TrEMBL
Match: A0A6J1I943 (probable gamma-secretase subunit PEN-2 OS=Cucurbita maxima OX=3661 GN=LOC111470312 PE=3 SV=1)

HSP 1 Score: 252 bits (644), Expect = 1.70e-84
Identity = 121/137 (88.32%), Postives = 125/137 (91.24%), Query Frame = 0

Query: 1   METLQNPNANTNSNP----NTISSPIRVLWPTIDGSLGLSEEESVSYARRFYKFGFALLP 60
           ME  QN N+N N NP    N +SSPI VLWPTIDGSLGLSEEESVSYARRFYKFGFALLP
Sbjct: 1   MENSQNSNSNLNPNPIRIQNLVSSPIAVLWPTIDGSLGLSEEESVSYARRFYKFGFALLP 60

Query: 61  FLWAVNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPVWD 120
           FLWAVNCFYFWPVLRSRSFPRIRPYIVGSAIGF VFMAIISSWALTF+IGGERLFGPVWD
Sbjct: 61  FLWAVNCFYFWPVLRSRSFPRIRPYIVGSAIGFAVFMAIISSWALTFAIGGERLFGPVWD 120

Query: 121 KLVMYNLADKVGLTGWS 133
           KLVMYNLADK+GLTGWS
Sbjct: 121 KLVMYNLADKLGLTGWS 137

BLAST of CsGy2G015760 vs. ExPASy TrEMBL
Match: A0A6J1F097 (probable gamma-secretase subunit PEN-2 OS=Cucurbita moschata OX=3662 GN=LOC111438306 PE=3 SV=1)

HSP 1 Score: 250 bits (639), Expect = 9.85e-84
Identity = 120/137 (87.59%), Postives = 124/137 (90.51%), Query Frame = 0

Query: 1   METLQNPNANTNSNP----NTISSPIRVLWPTIDGSLGLSEEESVSYARRFYKFGFALLP 60
           ME  QN N+N N NP    N +SSPI VLWPTIDGSLGLSEEESVSYARRFYKFGFALLP
Sbjct: 1   MENSQNSNSNPNPNPIRIQNLVSSPIAVLWPTIDGSLGLSEEESVSYARRFYKFGFALLP 60

Query: 61  FLWAVNCFYFWPVLRSRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPVWD 120
           FLWAVNCFYFWPVLRS SFPRIRPYIVGSAIGF VFMAIISSWALTF+IGGERLFGPVWD
Sbjct: 61  FLWAVNCFYFWPVLRSHSFPRIRPYIVGSAIGFAVFMAIISSWALTFAIGGERLFGPVWD 120

Query: 121 KLVMYNLADKVGLTGWS 133
           KLVMYNLADK+GLTGWS
Sbjct: 121 KLVMYNLADKLGLTGWS 137

BLAST of CsGy2G015760 vs. ExPASy TrEMBL
Match: A0A1S3CDI1 (probable gamma-secretase subunit PEN-2 OS=Cucumis melo OX=3656 GN=LOC103499635 PE=3 SV=1)

HSP 1 Score: 249 bits (637), Expect = 4.46e-83
Identity = 126/161 (78.26%), Postives = 128/161 (79.50%), Query Frame = 0

Query: 1   METLQNPNANTNSNPNTISSPIRVLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWA 60
           MET  NPNANTNSNPNTI+SPI VLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWA
Sbjct: 1   METSHNPNANTNSNPNTITSPIPVLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFLWA 60

Query: 61  VNCFYFWPVLRSRSFPRIRPY----------------------------IVGSAIGFGVF 120
           VNCFYFWPVLRSRSFPRIRP                             IVGSAIGFGV 
Sbjct: 61  VNCFYFWPVLRSRSFPRIRPSFQTVTLMLEFSRSITLEDTPFSRPFIIDIVGSAIGFGVS 120

Query: 121 MAIISSWALTFSIGGERLFGPVWDKLVMYNLADKVGLTGWS 133
           MAIISSWALTFSIGGERLFGPVWDKLVMYNLADK+GLTGWS
Sbjct: 121 MAIISSWALTFSIGGERLFGPVWDKLVMYNLADKLGLTGWS 161

BLAST of CsGy2G015760 vs. TAIR 10
Match: AT5G09310.1 (CONTAINS InterPro DOMAIN/s: Gamma-secretase aspartyl protease complex, presenilin enhancer-2 subunit (InterPro:IPR019379); Has 168 Blast hits to 168 proteins in 71 species: Archae - 0; Bacteria - 0; Metazoa - 126; Fungi - 0; Plants - 36; Viruses - 0; Other Eukaryotes - 6 (source: NCBI BLink). )

HSP 1 Score: 193.4 bits (490), Expect = 1.2e-49
Identity = 92/134 (68.66%), Postives = 113/134 (84.33%), Query Frame = 0

Query: 1   METLQNPNANTNSNPNTISSPI--RVLWPTIDGSLGLSEEESVSYARRFYKFGFALLPFL 60
           +  ++N N N N NPN +S+ I    +WPTIDG LGL+EE SV YARRFYKFGFALLP+L
Sbjct: 11  LNPIRNRNPNPNPNPNPLSTIISSAQVWPTIDGPLGLTEEASVDYARRFYKFGFALLPWL 70

Query: 61  WAVNCFYFWPVLR-SRSFPRIRPYIVGSAIGFGVFMAIISSWALTFSIGGERLFGPVWDK 120
           W VNCFYFWPVLR SR+FP+IR Y+V SAIGF VF A++S+WALTFSIGGE+LFGP++DK
Sbjct: 71  WFVNCFYFWPVLRHSRAFPQIRNYVVRSAIGFSVFTALLSAWALTFSIGGEQLFGPLYDK 130

Query: 121 LVMYNLADKVGLTG 132
           LVMYN+AD++GL+G
Sbjct: 131 LVMYNVADRLGLSG 144

The following BLAST results are available for this feature:
Match NameE-valueIdentityDescription
Q9FY841.7e-4868.66Probable gamma-secretase subunit PEN-2 OS=Arabidopsis thaliana OX=3702 GN=At5g09... [more]
Q5G2353.8e-0835.48Gamma-secretase subunit PEN-2 OS=Bos taurus OX=9913 GN=PSENEN PE=3 SV=1[more]
Q9NZ428.5e-0835.48Gamma-secretase subunit PEN-2 OS=Homo sapiens OX=9606 GN=PSENEN PE=1 SV=1[more]
Q9CQR71.5e-0735.48Gamma-secretase subunit PEN-2 OS=Mus musculus OX=10090 GN=Psenen PE=1 SV=1[more]
Q6QI681.9e-0734.41Gamma-secretase subunit PEN-2 OS=Rattus norvegicus OX=10116 GN=Psenen PE=3 SV=1[more]
Match NameE-valueIdentityDescription
XP_011649406.12.25e-95100.00probable gamma-secretase subunit PEN-2 [Cucumis sativus] >KGN62163.1 hypothetica... [more]
KAA0040759.11.71e-9095.49putative gamma-secretase subunit PEN-2 [Cucumis melo var. makuwa] >TYK02074.1 pu... [more]
XP_038900346.13.22e-8689.21probable gamma-secretase subunit PEN-2 [Benincasa hispida][more]
XP_022971629.13.51e-8488.32probable gamma-secretase subunit PEN-2 [Cucurbita maxima][more]
XP_022931973.12.03e-8387.59probable gamma-secretase subunit PEN-2 [Cucurbita moschata][more]
Match NameE-valueIdentityDescription
A0A0A0LK381.09e-95100.00Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_2G302290 PE=3 SV=1[more]
A0A5A7THJ98.30e-9195.49Putative gamma-secretase subunit PEN-2 OS=Cucumis melo var. makuwa OX=1194695 GN... [more]
A0A6J1I9431.70e-8488.32probable gamma-secretase subunit PEN-2 OS=Cucurbita maxima OX=3661 GN=LOC1114703... [more]
A0A6J1F0979.85e-8487.59probable gamma-secretase subunit PEN-2 OS=Cucurbita moschata OX=3662 GN=LOC11143... [more]
A0A1S3CDI14.46e-8378.26probable gamma-secretase subunit PEN-2 OS=Cucumis melo OX=3656 GN=LOC103499635 P... [more]
Match NameE-valueIdentityDescription
AT5G09310.11.2e-4968.66CONTAINS InterPro DOMAIN/s: Gamma-secretase aspartyl protease complex, presenili... [more]
InterPro
Analysis Name: InterPro Annotations of Cucumber (Gy14) v2.1
Date Performed: 2021-10-25
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR019379Gamma-secretase aspartyl protease complex, presenilin enhancer-2 subunitPFAMPF10251PEN-2coord: 37..123
e-value: 4.4E-28
score: 97.5
IPR019379Gamma-secretase aspartyl protease complex, presenilin enhancer-2 subunitPANTHERPTHR16318GAMMA-SECRETASE SUBUNIT PEN-2coord: 8..133

Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
CsGy2G015760.2CsGy2G015760.2mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007219 Notch signaling pathway
biological_process GO:0006508 proteolysis
cellular_component GO:0070765 gamma-secretase complex
cellular_component GO:0005798 Golgi-associated vesicle
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0008233 peptidase activity