Cp4.1LG02g08810 (gene) Cucurbita pepo (MU‐CU‐16) v4.1

Overview
NameCp4.1LG02g08810
Typegene
OrganismCucurbita pepo (Cucurbita pepo (MU‐CU‐16) v4.1)
DescriptionTranscription factor TCP23-like
LocationCp4.1LG02: 6516920 .. 6520571 (+)
RNA-Seq ExpressionCp4.1LG02g08810
SyntenyCp4.1LG02g08810
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDSpolypeptide
Hold the cursor over a type above to highlight its positions in the sequence below.
ATGGGTGCTTTTGTGATAATCTTAAACTAGAAGATGTAAAAATCTTGAGGCTTATTATTAACTTGTTTTTCTTTTAGTTGTTGTCTTAACATGGAGCCTTAACTCTCGACATGGTTAAAAAGTTCATCACTAACTTACATGTCGTACTAACATGAATCGACCAGACCACACCATGCAAATCAAAGAGAGTTTAAACCTCATTCAAACACCTCACTTAATTATAACACCACATTCAAACTGTATTGTTTAAAATTTCATGATGTTATCTAGTAAACTTTTCATATCTACGTACTCTATAGTAATGAAATTTTCCTTCGTCACTACCCTTTTCAGTATCCAGAGCAACCTATAAGATAATATCATCTACCGTACTTCCCTAGTATATATTCGTTGGACAACTTACTAGTATTTGTTTGTACATTCTTTTCCATCTTTATGGTTATAATACTATGTCATTTAACTATGTTTCAAGACATCCGACTGAAACATCTAATATTTTTTTAGTAAAGTCATTTTTTCAGATAAAATTATGTTAAACCTAAACATGCTCCAAATCATCAATACATCAGGTAGCATTCATATTTCATGTCTAATAATTATAACATGATATAGAAACATCATATATTATATTTCATAGGACATGCCTGACGGTGACGCGACATTTGCGGTAAGGCCATGGAATACTCTAAGCCTACCTTTTTCTAACAATAAAATGGCTGATACATGCATGTTTGGGTACTTGATTAACAAAGTTTAGAAATAAATATGTTATCGCCCTAATTAGTGACTTGTGTATAAATGGCTTCCCTGCTACAAATCAGAATTCAATTGATCTTCGTCACTGTGAAACCAAATTGTAAGCCAAGAATTCTCTCTTTCTCGTTTATCTGATTTCATGATTCTTTCTCGTTTCTTGATCGGTCTTAGATTTTGAACTCTGCCTTGATTTTGACTTTATTTCTCTCTTATTTGTTATTGTCGTGATCGATTACAAGTTATTGACGCTGTCCGTCTCTATAGGCTTCTATTAATCTTCAGGCTCCATTTCTGATGGATTTTTGTAGTTTCGTTGCTGCGACGTTCAGATCTTTGGATTTTCTTCTCGACTACTCGTTTGTTTCGGACATTTTTCTCAATTGCATCTTTCAATGATCTGAAATGAAACATTAGGACAGTCCCTTTAAATATCTCTATATTTATACGAAGAAGTTAATGACGGCGAAGAATTTATGATTTCCATTTTATTATTTCTCCCCATCTAGTCCTATTCGAAAAGGCTGGGATATTCGTTGTATCCGTTTGTGTTTAATTGTTTGTTGCGTTTCGTATTTGCTAATGGTAGTTTAAAGCTTTCGATTATTTATTAGCCTTTTACAGATCATAAACGGTGGAGTATATACAACAATCCTCCAAAATACTGGAGTTTCTGCCTACTGCCTAAATCAACAATTTGCAATCAAGTTTTTTGCAAAACGTATCTTTAAACATTAATCGGATTTCAGATATTTAGTTTTTTGTTTCCTGTGACAATGAGCTCTCCCGTTCCCTGCTTACACAACTGGCTAGTAGTAACTATTTGTATTCTATGATTTTCTAAAACTTATCTTACTTGTATAGGATCTCTTGTTGAGGATATAAGTGAAAAGGGGGAACTAATTGCGAGCAGAGAAAATGTCCTTCGGCAATGGAGTGAAATCCTGTGCACAGCTGCTGAAGTCTTCATAACCATTGTTGGTGAAATCAGGTTTCCTTACCTTGTTAGCCATGATGCAGATTTACTTCAACTTATGTTTTACAATTCCTGCATATGCTTGTTAGTTGCAATAATCTTTCTGAAATTCATAAGAGTGTAGTTATAGCATACTCTGACATGATTGTAAATAAGGAAACAAGCAAACCATTAATTAAAAATAAGTGATGTGAAAGAAATTGCACAACAATGACAGTAATAAAAAGGACTCATTGAAGCAATGAACATCGCCGAAGATCTATGCGTGGGAGAAGATTAAAGCATCGAACACCATGGAGTTCTAAGAAAATAAATCTGAACAGGATAACAAGTTCCTACGAACAAGTATTTATGGATAGCTCTGCTAAAATGGCTAAGTAAGACCTTCAGCAGGTTGTGATATAGGCTTTTTTGCCTATTATTACTTGGGCCTTCCTCTTGGTAACGTTCCTGTAAGTTTTTTGTTTCTGAGATCTAGTTGTGGAAAAGGTCAAAAAATGCTTCTCCTCGTGGAAGGGGAGTTTTTTTTTTTTTTCCTTCTTTCTAACGGAAGTAGTCAAACTTTATCTTATCTGGTTTGTTTTTAGTGGAATCTCAACTTTCTTGCTCCATTTGTTTAGGGTTCTCGTTTTGTTCAACAAGAGACTAGAAAAGCTTATAAGTGACTTCTTACGAGAAGGGGTTGATGAGGTTCGAACATTGCTTTACTCAAGTGGGAGGTTGTGGCCAAGCTGTTCGATCTTGGGCATTTAGATATTGGTAATTTGAGGGATCAAAACGAAGTCTTGTTGGTTAAATGGTTGTGGTGCTTTCCTTGGGGGACTGCACCTTGTGGCATATGACTATTGTGATACTGTATACGAAGTCTTGTTGATGTTTACTTCCCCTGAAAATCATGGATAGAACAAATTTCTAATTTTCTAGTCAATGAAGGATACTGTATGCTTTCATATTGGTATATTTTTTAAAAATGTATATTCTAGTAAACGTGTCCTTGCTGCATCTATGTCCTAGTATCTTAGAAGGCGATGTGTTTCATCGATAATTGTCTGTTCATTTCTACTAATTCATAGGGTTCATATATATGAATCAAGGTTTTTAAATCCTAAAAATGATGGTTTTGTGGCACAGCTAATCGAGGGTTTCACTCAAACTGGTGTGAAGAGAATGGGAGGACATGCACATGGACACGATGAACCCTACTATTTGCACGCAAAGCACATGTACAACTTGGATAGGATGAAAAATCAGAAGTTGAGCATGAGGCTTGGAGTTTTCACTGCATTCAGCATAGGTGTGGGCGTTCCAATCTATGCAGTCATGTTTCAGCAAAAGAAGACGGCCTCTGTATGATATTCTTCCCTCAAACAATGTGTGCAACCCAATAAGAAACATCGGTTGCACCTAAGTCAGTCGTGGAATCCCGTGTGAATCAGCAAGGATCACCTTGNTTCTCCCCCGGATGAACCATATAGCCAAGAGAAACCATGAACCAGAATAGAAGAACTTGCCTCTTCTCTCCTCTCCTTGGTTTTATCTATAAACCCTCATTTCAAATGCGGGATAGATACTCAGAAAGTCGATTCTGTTTTCCTCAATAAGTCTTTTCATCATAATTTCGTTATATTCCACATTTTGATCCAATCTATTTTACTACCCAAAGATTTTTTATTGTTTGGGTTCGTTCGTTCATTCATTCCTTCCCTCCATTTTTATTTAGTTTGCCCCTAACCATTTTCTTTATATCAGGGAATATGATATGTTGTATGGTTGGAGGAAATGATAACCTTGTAGATTTTCTGTAGTTTCTCTTAAGCTAATTTATCCCTTCCTTTTGTTTTACAAATGTTTCATTTATTTCAACTTATATATTTTAAGATATTATCACCTTTTAGAGGAAGTAGAGTTATAGTTAAGAATTGA

mRNA sequence

ATGGGATCTCTTGTTGAGGATATAAGTGAAAAGGGGGAACTAATTGCGAGCAGAGAAAATGTCCTTCGGCAATGGAGTGAAATCCTGTGCACAGCTGCTGAAGTCTTCATAACCATTGTTGGTGAAATCAGGGTTCATATATATGAATCAAGGTTTTTAAATCCTAAAAATGATGGTTTTGTGGCACAGCTAATCGAGGGTTTCACTCAAACTGGTGTGAAGAGAATGGGAGGACATGCACATGGACACGATGAACCCTACTATTTGCACGCAAAGCACATGTACAACTTGGATAGGATGAAAAATCAGAAGTTGAGCATGAGGCTTGGAGTTTTCACTGCATTCAGCATAGGTGTGGGCGTTCCAATCTATGCAGTCATGTTTCAGCAAAAGAAGACGGCCTCTATATTATCACCTTTTAGAGGAAGTAGAGTTATAGTTAAGAATTGA

Coding sequence (CDS)

ATGGGATCTCTTGTTGAGGATATAAGTGAAAAGGGGGAACTAATTGCGAGCAGAGAAAATGTCCTTCGGCAATGGAGTGAAATCCTGTGCACAGCTGCTGAAGTCTTCATAACCATTGTTGGTGAAATCAGGGTTCATATATATGAATCAAGGTTTTTAAATCCTAAAAATGATGGTTTTGTGGCACAGCTAATCGAGGGTTTCACTCAAACTGGTGTGAAGAGAATGGGAGGACATGCACATGGACACGATGAACCCTACTATTTGCACGCAAAGCACATGTACAACTTGGATAGGATGAAAAATCAGAAGTTGAGCATGAGGCTTGGAGTTTTCACTGCATTCAGCATAGGTGTGGGCGTTCCAATCTATGCAGTCATGTTTCAGCAAAAGAAGACGGCCTCTATATTATCACCTTTTAGAGGAAGTAGAGTTATAGTTAAGAATTGA

Protein sequence

MGSLVEDISEKGELIASRENVLRQWSEILCTAAEVFITIVGEIRVHIYESRFLNPKNDGFVAQLIEGFTQTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAVMFQQKKTASILSPFRGSRVIVKN
Homology
[Close]
BLAST of Cp4.1LG02g08810 vs. NCBI nr
Match: KAG6607652.1 (hypothetical protein SDJN03_00994, partial [Cucurbita argyrosperma subsp. sororia])

HSP 1 Score: 141 bits (356), Expect = 1.33e-40
Identity = 67/69 (97.10%), Postives = 67/69 (97.10%), Query Frame = 0 

Query: 67  GFTQTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV 126
           GF  TGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV
Sbjct: 28  GFHSTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV 87

Query: 127 MFQQKKTAS 135
           MFQQKKTAS
Sbjct: 88  MFQQKKTAS 96

[Close]
BLAST of Cp4.1LG02g08810 vs. NCBI nr
Match: KAG7037254.1 (hypothetical protein SDJN02_00877, partial [Cucurbita argyrosperma subsp. argyrosperma])

HSP 1 Score: 139 bits (351), Expect = 7.64e-40
Identity = 66/69 (95.65%), Postives = 66/69 (95.65%), Query Frame = 0 

Query: 67  GFTQTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV 126
           GF  TGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVF AFSIGVGVPIYAV
Sbjct: 28  GFHSTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFAAFSIGVGVPIYAV 87

Query: 127 MFQQKKTAS 135
           MFQQKKTAS
Sbjct: 88  MFQQKKTAS 96

[Close]
BLAST of Cp4.1LG02g08810 vs. NCBI nr
Match: XP_022926198.1 (uncharacterized protein LOC111433382 [Cucurbita moschata])

HSP 1 Score: 139 bits (350), Expect = 1.08e-39
Identity = 66/69 (95.65%), Postives = 66/69 (95.65%), Query Frame = 0 

Query: 67  GFTQTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV 126
           G   TGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV
Sbjct: 28  GLHSTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV 87

Query: 127 MFQQKKTAS 135
           MFQQKKTAS
Sbjct: 88  MFQQKKTAS 96

[Close]
BLAST of Cp4.1LG02g08810 vs. NCBI nr
Match: XP_022981661.1 (uncharacterized protein LOC111480717 [Cucurbita maxima] >XP_022981663.1 uncharacterized protein LOC111480717 [Cucurbita maxima])

HSP 1 Score: 137 bits (346), Expect = 4.40e-39
Identity = 65/69 (94.20%), Postives = 66/69 (95.65%), Query Frame = 0 

Query: 67  GFTQTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV 126
           GF  T VKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV
Sbjct: 28  GFHSTAVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV 87

Query: 127 MFQQKKTAS 135
           +FQQKKTAS
Sbjct: 88  IFQQKKTAS 96

[Close]
BLAST of Cp4.1LG02g08810 vs. NCBI nr
Match: XP_038899385.1 (uncharacterized protein LOC120086696 [Benincasa hispida])

HSP 1 Score: 135 bits (341), Expect = 2.53e-38
Identity = 65/86 (75.58%), Postives = 69/86 (80.23%), Query Frame = 0 

Query: 50  SRFLNPKNDGFVAQLIEGFTQTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRL 109
           ++ L       V     GF  TGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKL+M L
Sbjct: 11  AKLLKSSESLLVKSANRGFHSTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLTMTL 70

Query: 110 GVFTAFSIGVGVPIYAVMFQQKKTAS 135
           GVFTAFSIGV VPIYAV+FQQKKTAS
Sbjct: 71  GVFTAFSIGVAVPIYAVIFQQKKTAS 96

[Close]
BLAST of Cp4.1LG02g08810 vs. ExPASy TrEMBL
Match: A0A6J1EHC8 (uncharacterized protein LOC111433382 OS=Cucurbita moschata OX=3662 GN=LOC111433382 PE=4 SV=1)

HSP 1 Score: 139 bits (350), Expect = 5.25e-40
Identity = 66/69 (95.65%), Postives = 66/69 (95.65%), Query Frame = 0 

Query: 67  GFTQTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV 126
           G   TGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV
Sbjct: 28  GLHSTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV 87

Query: 127 MFQQKKTAS 135
           MFQQKKTAS
Sbjct: 88  MFQQKKTAS 96

[Close]
BLAST of Cp4.1LG02g08810 vs. ExPASy TrEMBL
Match: A0A6J1J2Q3 (uncharacterized protein LOC111480717 OS=Cucurbita maxima OX=3661 GN=LOC111480717 PE=4 SV=1)

HSP 1 Score: 137 bits (346), Expect = 2.13e-39
Identity = 65/69 (94.20%), Postives = 66/69 (95.65%), Query Frame = 0 

Query: 67  GFTQTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV 126
           GF  T VKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV
Sbjct: 28  GFHSTAVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV 87

Query: 127 MFQQKKTAS 135
           +FQQKKTAS
Sbjct: 88  IFQQKKTAS 96

[Close]
BLAST of Cp4.1LG02g08810 vs. ExPASy TrEMBL
Match: A0A6J1CR70 (uncharacterized protein LOC111013498 OS=Momordica charantia OX=3673 GN=LOC111013498 PE=4 SV=1)

HSP 1 Score: 133 bits (334), Expect = 1.42e-37
Identity = 63/86 (73.26%), Postives = 68/86 (79.07%), Query Frame = 0 

Query: 50  SRFLNPKNDGFVAQLIEGFTQTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRL 109
           ++ L       +     GF  TG KRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKL+M L
Sbjct: 11  AKLLRSSESLLMKSANRGFHSTGAKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLTMTL 70

Query: 110 GVFTAFSIGVGVPIYAVMFQQKKTAS 135
           GVFTAFSIGV VPIYAV+FQQKKTAS
Sbjct: 71  GVFTAFSIGVAVPIYAVIFQQKKTAS 96

[Close]
BLAST of Cp4.1LG02g08810 vs. ExPASy TrEMBL
Match: A0A1S3B3R2 (uncharacterized protein LOC103485430 OS=Cucumis melo OX=3656 GN=LOC103485430 PE=4 SV=1)

HSP 1 Score: 132 bits (332), Expect = 2.86e-37
Identity = 64/86 (74.42%), Postives = 68/86 (79.07%), Query Frame = 0 

Query: 50  SRFLNPKNDGFVAQLIEGFTQTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRL 109
           ++ L       V     GF  TGVKRMGGHAHGHDEPYYLHAKHMYNLDRMK QKL+M L
Sbjct: 11  AKLLKSSEPLLVKSANRGFHSTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKYQKLTMTL 70

Query: 110 GVFTAFSIGVGVPIYAVMFQQKKTAS 135
           GV TAFSIGVGVPIYAV+FQQKKTAS
Sbjct: 71  GVLTAFSIGVGVPIYAVVFQQKKTAS 96

[Close]
BLAST of Cp4.1LG02g08810 vs. ExPASy TrEMBL
Match: A0A0A0LQ20 (Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_2G403690 PE=4 SV=1)

HSP 1 Score: 131 bits (329), Expect = 8.16e-37
Identity = 62/69 (89.86%), Postives = 64/69 (92.75%), Query Frame = 0 

Query: 67  GFTQTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAV 126
           GF  TGVKRMGGHAHGHDEPYYLHAKHMYNLDRMK QKL+M LGV TAFSIGVGVPIYAV
Sbjct: 28  GFHSTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKYQKLTMTLGVLTAFSIGVGVPIYAV 87

Query: 127 MFQQKKTAS 135
           +FQQKKTAS
Sbjct: 88  VFQQKKTAS 96

[Close]
BLAST of Cp4.1LG02g08810 vs. TAIR 10
Match: AT1G72020.1 (unknown protein; Has 52 Blast hits to 52 proteins in 18 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 52; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink). )

HSP 1 Score: 103.2 bits (256), Expect = 1.8e-22
Identity = 50/68 (73.53%), Postives = 55/68 (80.88%), Query Frame = 0 

Query: 68  FTQTGVKRMGGHAHGHDEPYYLHAKHMYNLDRMKNQKLSMRLGVFTAFSIGVGVPIYAVM 127
           F  TGVK+M G  HG  + YYLHAKHMYNLDRMK Q L M LGVFTAFSIGVGVPI+AV+
Sbjct: 29  FHSTGVKKMSGGGHGGYDEYYLHAKHMYNLDRMKYQALKMSLGVFTAFSIGVGVPIFAVV 88

Query: 128 FQQKKTAS 136
           FQQ+KT S
Sbjct: 89  FQQRKTQS 96

The following BLAST results are available for this feature:
BLAST of Cp4.1LG02g08810 vs.
Match NameE-valueIdentityDescription
BLAST of Cp4.1LG02g08810 vs. NCBI nr
Match NameE-valueIdentityDescription
KAG6607652.11.33e-4097.10hypothetical protein SDJN03_00994, partial [Cucurbita argyrosperma subsp. sorori... [more]
KAG7037254.17.64e-4095.65hypothetical protein SDJN02_00877, partial [Cucurbita argyrosperma subsp. argyro... [more]
XP_022926198.11.08e-3995.65uncharacterized protein LOC111433382 [Cucurbita moschata][more]
XP_022981661.14.40e-3994.20uncharacterized protein LOC111480717 [Cucurbita maxima] >XP_022981663.1 uncharac... [more]
XP_038899385.12.53e-3875.58uncharacterized protein LOC120086696 [Benincasa hispida][more]
BLAST of Cp4.1LG02g08810 vs. ExPASy TrEMBL
Match NameE-valueIdentityDescription
A0A6J1EHC85.25e-4095.65uncharacterized protein LOC111433382 OS=Cucurbita moschata OX=3662 GN=LOC1114333... [more]
A0A6J1J2Q32.13e-3994.20uncharacterized protein LOC111480717 OS=Cucurbita maxima OX=3661 GN=LOC111480717... [more]
A0A6J1CR701.42e-3773.26uncharacterized protein LOC111013498 OS=Momordica charantia OX=3673 GN=LOC111013... [more]
A0A1S3B3R22.86e-3774.42uncharacterized protein LOC103485430 OS=Cucumis melo OX=3656 GN=LOC103485430 PE=... [more]
A0A0A0LQ208.16e-3789.86Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_2G403690 PE=4 SV=1[more]
BLAST of Cp4.1LG02g08810 vs. TAIR 10
Match NameE-valueIdentityDescription
AT1G72020.11.8e-2273.53unknown protein; Has 52 Blast hits to 52 proteins in 18 species: Archae - 0; Bac... [more]
InterPro
Analysis Name: InterPro Annotations of Cucurbita pepo (Zucchini) v1
Date Performed: 2021-10-25
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePANTHERPTHR36003:SF5TONB-DEPENDENT HEME RECEPTOR Acoord: 61..135
NoneNo IPR availablePANTHERPTHR36003TONB-DEPENDENT HEME RECEPTOR Acoord: 61..135

Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
Cp4.1LG02g08810.1Cp4.1LG02g08810.1mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
cellular_component GO:0016021 integral component of membrane