CmaCh19G006370 (gene) Cucurbita maxima (Rimu) v1.1

Overview


Name	CmaCh19G006370
Type	gene
Organism	Cucurbita maxima (Cucurbita maxima (Rimu) v1.1)
Description	diphthamide biosynthesis protein 3-like
Location	Cma_Chr19: 6794623 .. 6794880 (-)
RNA-Seq Expression	CmaCh19G006370
Synteny	CmaCh19G006370

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDSpolypeptide

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGTCGTACGACGACGTGGAGATTGAAGACATGGAGTGGAATGAGGAACTGCAGGCCTTCACGTACCCATGCCCTTGCGGCGACTTGTTCCAGATTACGAAGGAGGATCTTAAGCTCGGTGAAGAGATTGCTCGGTGCCCTAGCTGTTCTCTTTACATCACAGTTATCTACAACATGGAAGATTTTCTCGGAGACTCTGATCACAAGAATAACAAAGGACTTCAGCCCTCCAAGCAACAGCCTATCGTTGTCGCTTGA

mRNA sequence

ATGTCGTACGACGACGTGGAGATTGAAGACATGGAGTGGAATGAGGAACTGCAGGCCTTCACGTACCCATGCCCTTGCGGCGACTTGTTCCAGATTACGAAGGAGGATCTTAAGCTCGGTGAAGAGATTGCTCGGTGCCCTAGCTGTTCTCTTTACATCACAGTTATCTACAACATGGAAGATTTTCTCGGAGACTCTGATCACAAGAATAACAAAGGACTTCAGCCCTCCAAGCAACAGCCTATCGTTGTCGCTTGA

Coding sequence (CDS)

ATGTCGTACGACGACGTGGAGATTGAAGACATGGAGTGGAATGAGGAACTGCAGGCCTTCACGTACCCATGCCCTTGCGGCGACTTGTTCCAGATTACGAAGGAGGATCTTAAGCTCGGTGAAGAGATTGCTCGGTGCCCTAGCTGTTCTCTTTACATCACAGTTATCTACAACATGGAAGATTTTCTCGGAGACTCTGATCACAAGAATAACAAAGGACTTCAGCCCTCCAAGCAACAGCCTATCGTTGTCGCTTGA

Protein sequence

MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNMEDFLGDSDHKNNKGLQPSKQQPIVVA

Homology

[Close]

BLAST of CmaCh19G006370 vs. ExPASy Swiss-Prot
Match: Q9VGQ9 (DPH3 homolog OS=Drosophila melanogaster OX=7227 GN=CG14701 PE=3 SV=1)

HSP 1 Score: 91.3 bits (225), Expect = 5.8e-18
Identity = 39/68 (57.35%), Postives = 52/68 (76.47%), Query Frame = 0


Query: 3  YDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNMEDF 62
          +D+VEIED E++EE + + YPCPCGD FQI+KE+L  GEE+A CPSCSL I VIY+ E F
Sbjct: 5  HDEVEIEDFEYDEEEEMYYYPCPCGDRFQISKEELIEGEEVATCPSCSLVIKVIYDPEMF 64

Query: 63 LGDSDHKN 71
            + D ++
Sbjct: 65 KAEEDEES 72

[Close]

BLAST of CmaCh19G006370 vs. ExPASy Swiss-Prot
Match: Q21102 (DPH3 homolog OS=Caenorhabditis elegans OX=6239 GN=K01H12.1 PE=3 SV=1)

HSP 1 Score: 89.7 bits (221), Expect = 1.7e-17
Identity = 36/61 (59.02%), Postives = 50/61 (81.97%), Query Frame = 0


Query: 3  YDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNMEDF 62
          +D+VEIED E++EE   + YPCPCGD F+I +E L++GE++A+CPSCSL I VIY+ EDF
Sbjct: 5  HDEVEIEDFEFDEEKDVYHYPCPCGDRFEIPREMLEMGEDVAQCPSCSLLIRVIYDPEDF 64

Query: 63 L 64
          +
Sbjct: 65 V 65

[Close]

BLAST of CmaCh19G006370 vs. ExPASy Swiss-Prot
Match: Q6VUC1 (DPH3 homolog OS=Cricetulus griseus OX=10029 GN=DPH3 PE=3 SV=1)

HSP 1 Score: 89.0 bits (219), Expect = 2.9e-17
Identity = 35/61 (57.38%), Postives = 49/61 (80.33%), Query Frame = 0


Query: 3  YDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNMEDF 62
          +D+VEIED +++E+ + + YPCPCGD F ITKEDL+ GE++A CPSCSL I VIY+ + F
Sbjct: 5  HDEVEIEDFQYDEDSETYFYPCPCGDNFSITKEDLENGEDVATCPSCSLIIKVIYDKDQF 64

Query: 63 L 64
          +
Sbjct: 65 M 65

[Close]

BLAST of CmaCh19G006370 vs. ExPASy Swiss-Prot
Match: Q96FX2 (DPH3 homolog OS=Homo sapiens OX=9606 GN=DPH3 PE=1 SV=1)

HSP 1 Score: 88.6 bits (218), Expect = 3.7e-17
Identity = 35/61 (57.38%), Postives = 49/61 (80.33%), Query Frame = 0


Query: 3  YDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNMEDF 62
          +D+VEIED +++E+ + + YPCPCGD F ITKEDL+ GE++A CPSCSL I VIY+ + F
Sbjct: 5  HDEVEIEDFQYDEDSETYFYPCPCGDNFSITKEDLENGEDVATCPSCSLIIKVIYDKDQF 64

Query: 63 L 64
          +
Sbjct: 65 V 65

[Close]

BLAST of CmaCh19G006370 vs. ExPASy Swiss-Prot
Match: Q4R312 (DPH3 homolog OS=Macaca fascicularis OX=9541 GN=DPH3 PE=3 SV=1)

HSP 1 Score: 88.6 bits (218), Expect = 3.7e-17
Identity = 35/61 (57.38%), Postives = 49/61 (80.33%), Query Frame = 0


Query: 3  YDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNMEDF 62
          +D+VEIED +++E+ + + YPCPCGD F ITKEDL+ GE++A CPSCSL I VIY+ + F
Sbjct: 5  HDEVEIEDFQYDEDSETYFYPCPCGDNFSITKEDLENGEDVATCPSCSLIIKVIYDKDQF 64

Query: 63 L 64
          +
Sbjct: 65 V 65

[Close]

BLAST of CmaCh19G006370 vs. ExPASy TrEMBL
Match: A0A6J1I4L9 (diphthamide biosynthesis protein 3-like OS=Cucurbita maxima OX=3661 GN=LOC111470942 PE=4 SV=1)

HSP 1 Score: 186.8 bits (473), Expect = 3.7e-44
Identity = 85/85 (100.00%), Postives = 85/85 (100.00%), Query Frame = 0


Query: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60
          MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME
Sbjct: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60

Query: 61 DFLGDSDHKNNKGLQPSKQQPIVVA 86
          DFLGDSDHKNNKGLQPSKQQPIVVA
Sbjct: 61 DFLGDSDHKNNKGLQPSKQQPIVVA 85

[Close]

BLAST of CmaCh19G006370 vs. ExPASy TrEMBL
Match: A0A6J1C519 (diphthamide biosynthesis protein 3-like OS=Momordica charantia OX=3673 GN=LOC111007992 PE=4 SV=1)

HSP 1 Score: 179.5 bits (454), Expect = 6.0e-42
Identity = 80/85 (94.12%), Postives = 84/85 (98.82%), Query Frame = 0


Query: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60
          MSYDDVEIEDMEWN+ELQA+TYPCPCGDLFQITKEDL+LGEEIARCPSCSLYITVIYNME
Sbjct: 1  MSYDDVEIEDMEWNQELQAYTYPCPCGDLFQITKEDLRLGEEIARCPSCSLYITVIYNME 60

Query: 61 DFLGDSDHKNNKGLQPSKQQPIVVA 86
          DFLGDSD KNNKG+QPSKQQPIVVA
Sbjct: 61 DFLGDSDQKNNKGIQPSKQQPIVVA 85

[Close]

BLAST of CmaCh19G006370 vs. ExPASy TrEMBL
Match: A0A1S3BZL5 (diphthamide biosynthesis protein 3-like OS=Cucumis melo OX=3656 GN=LOC103495198 PE=4 SV=1)

HSP 1 Score: 174.9 bits (442), Expect = 1.5e-40
Identity = 79/85 (92.94%), Postives = 82/85 (96.47%), Query Frame = 0


Query: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60
          MSYDDVEIEDM+WNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME
Sbjct: 1  MSYDDVEIEDMDWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60

Query: 61 DFLGDSDHKNNKGLQPSKQQPIVVA 86
          DFL DS+ KNNKGL+PSKQ PIVVA
Sbjct: 61 DFLDDSNQKNNKGLEPSKQHPIVVA 85

[Close]

BLAST of CmaCh19G006370 vs. ExPASy TrEMBL
Match: A0A5A7SJN1 (Diphthamide biosynthesis protein 3-like OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold13G00150 PE=4 SV=1)

HSP 1 Score: 174.9 bits (442), Expect = 1.5e-40
Identity = 79/85 (92.94%), Postives = 82/85 (96.47%), Query Frame = 0


Query: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60
          MSYDDVEIEDM+WNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME
Sbjct: 1  MSYDDVEIEDMDWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60

Query: 61 DFLGDSDHKNNKGLQPSKQQPIVVA 86
          DFL DS+ KNNKGL+PSKQ PIVVA
Sbjct: 61 DFLDDSNQKNNKGLEPSKQHPIVVA 85

[Close]

BLAST of CmaCh19G006370 vs. ExPASy TrEMBL
Match: A0A6J1EZW6 (diphthamide biosynthesis protein 3-like OS=Cucurbita moschata OX=3662 GN=LOC111437758 PE=4 SV=1)

HSP 1 Score: 173.3 bits (438), Expect = 4.3e-40
Identity = 79/85 (92.94%), Postives = 81/85 (95.29%), Query Frame = 0


Query: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60
          MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME
Sbjct: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60

Query: 61 DFLGDSDHKNNKGLQPSKQQPIVVA 86
          DFLGDS  KNN GL+PSKQ+P VVA
Sbjct: 61 DFLGDSVQKNNTGLEPSKQRPAVVA 85

[Close]

BLAST of CmaCh19G006370 vs. NCBI nr
Match: XP_022972367.1 (diphthamide biosynthesis protein 3-like [Cucurbita maxima])

HSP 1 Score: 186.8 bits (473), Expect = 7.7e-44
Identity = 85/85 (100.00%), Postives = 85/85 (100.00%), Query Frame = 0


Query: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60
          MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME
Sbjct: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60

Query: 61 DFLGDSDHKNNKGLQPSKQQPIVVA 86
          DFLGDSDHKNNKGLQPSKQQPIVVA
Sbjct: 61 DFLGDSDHKNNKGLQPSKQQPIVVA 85

[Close]

BLAST of CmaCh19G006370 vs. NCBI nr
Match: XP_038887330.1 (diphthamide biosynthesis protein 3-like [Benincasa hispida] >XP_038887331.1 diphthamide biosynthesis protein 3-like [Benincasa hispida])

HSP 1 Score: 180.6 bits (457), Expect = 5.5e-42
Identity = 82/85 (96.47%), Postives = 84/85 (98.82%), Query Frame = 0


Query: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60
          MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME
Sbjct: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60

Query: 61 DFLGDSDHKNNKGLQPSKQQPIVVA 86
          DFLGDS+ KNNKGL+PSKQQPIVVA
Sbjct: 61 DFLGDSNQKNNKGLEPSKQQPIVVA 85

[Close]

BLAST of CmaCh19G006370 vs. NCBI nr
Match: XP_022136247.1 (diphthamide biosynthesis protein 3-like [Momordica charantia])

HSP 1 Score: 179.5 bits (454), Expect = 1.2e-41
Identity = 80/85 (94.12%), Postives = 84/85 (98.82%), Query Frame = 0


Query: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60
          MSYDDVEIEDMEWN+ELQA+TYPCPCGDLFQITKEDL+LGEEIARCPSCSLYITVIYNME
Sbjct: 1  MSYDDVEIEDMEWNQELQAYTYPCPCGDLFQITKEDLRLGEEIARCPSCSLYITVIYNME 60

Query: 61 DFLGDSDHKNNKGLQPSKQQPIVVA 86
          DFLGDSD KNNKG+QPSKQQPIVVA
Sbjct: 61 DFLGDSDQKNNKGIQPSKQQPIVVA 85

[Close]

BLAST of CmaCh19G006370 vs. NCBI nr
Match: XP_008454889.1 (PREDICTED: diphthamide biosynthesis protein 3-like [Cucumis melo] >XP_008454890.1 PREDICTED: diphthamide biosynthesis protein 3-like [Cucumis melo] >KAA0031262.1 diphthamide biosynthesis protein 3-like [Cucumis melo var. makuwa] >TYK06714.1 diphthamide biosynthesis protein 3-like [Cucumis melo var. makuwa])

HSP 1 Score: 174.9 bits (442), Expect = 3.0e-40
Identity = 79/85 (92.94%), Postives = 82/85 (96.47%), Query Frame = 0


Query: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60
          MSYDDVEIEDM+WNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME
Sbjct: 1  MSYDDVEIEDMDWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60

Query: 61 DFLGDSDHKNNKGLQPSKQQPIVVA 86
          DFL DS+ KNNKGL+PSKQ PIVVA
Sbjct: 61 DFLDDSNQKNNKGLEPSKQHPIVVA 85

[Close]

BLAST of CmaCh19G006370 vs. NCBI nr
Match: XP_022931585.1 (diphthamide biosynthesis protein 3-like [Cucurbita moschata])

HSP 1 Score: 173.3 bits (438), Expect = 8.8e-40
Identity = 79/85 (92.94%), Postives = 81/85 (95.29%), Query Frame = 0


Query: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60
          MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME
Sbjct: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60

Query: 61 DFLGDSDHKNNKGLQPSKQQPIVVA 86
          DFLGDS  KNN GL+PSKQ+P VVA
Sbjct: 61 DFLGDSVQKNNTGLEPSKQRPAVVA 85

[Close]

BLAST of CmaCh19G006370 vs. TAIR 10
Match: AT2G15910.2 (CSL zinc finger domain-containing protein )

HSP 1 Score: 143.7 bits (361), Expect = 7.0e-35
Identity = 66/85 (77.65%), Postives = 73/85 (85.88%), Query Frame = 0


Query: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60
          MSYDDVEIEDMEWNEE+QA+TYPCPCGDLFQITKEDL+LGEEIA CPSCSLYITVIYNME
Sbjct: 1  MSYDDVEIEDMEWNEEIQAYTYPCPCGDLFQITKEDLRLGEEIANCPSCSLYITVIYNME 60

Query: 61 DFLGDSDHKNNKGLQPSKQQPIVVA 86
          DF  D+  KNN   +P  + P+ VA
Sbjct: 61 DFQNDT-KKNN---EPKTRHPVAVA 81

[Close]

BLAST of CmaCh19G006370 vs. TAIR 10
Match: AT2G15910.1 (CSL zinc finger domain-containing protein )

HSP 1 Score: 139.8 bits (351), Expect = 1.0e-33
Identity = 64/82 (78.05%), Postives = 71/82 (86.59%), Query Frame = 0


Query: 1  MSYDDVEIEDMEWNEELQAFTYPCPCGDLFQITKEDLKLGEEIARCPSCSLYITVIYNME 60
          MSYDDVEIEDMEWNEE+QA+TYPCPCGDLFQITKEDL+LGEEIA CPSCSLYITVIYNME
Sbjct: 1  MSYDDVEIEDMEWNEEIQAYTYPCPCGDLFQITKEDLRLGEEIANCPSCSLYITVIYNME 60

Query: 61 DFLGDSDHKNNKGLQPSKQQPI 83
          DF  D+  KNN   +P  + P+
Sbjct: 61 DFQNDT-KKNN---EPKTRHPV 78

The following BLAST results are available for this feature:

BLAST of CmaCh19G006370 vs. ExPASy Swiss-Prot


Match Name	E-value	Identity	Description
Q9VGQ9	5.8e-18	57.35	DPH3 homolog OS=Drosophila melanogaster OX=7227 GN=CG14701 PE=3 SV=1	[more]
Q21102	1.7e-17	59.02	DPH3 homolog OS=Caenorhabditis elegans OX=6239 GN=K01H12.1 PE=3 SV=1	[more]
Q6VUC1	2.9e-17	57.38	DPH3 homolog OS=Cricetulus griseus OX=10029 GN=DPH3 PE=3 SV=1	[more]
Q96FX2	3.7e-17	57.38	DPH3 homolog OS=Homo sapiens OX=9606 GN=DPH3 PE=1 SV=1	[more]
Q4R312	3.7e-17	57.38	DPH3 homolog OS=Macaca fascicularis OX=9541 GN=DPH3 PE=3 SV=1	[more]

BLAST of CmaCh19G006370 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A6J1I4L9	3.7e-44	100.00	diphthamide biosynthesis protein 3-like OS=Cucurbita maxima OX=3661 GN=LOC111470...	[more]
A0A6J1C519	6.0e-42	94.12	diphthamide biosynthesis protein 3-like OS=Momordica charantia OX=3673 GN=LOC111...	[more]
A0A1S3BZL5	1.5e-40	92.94	diphthamide biosynthesis protein 3-like OS=Cucumis melo OX=3656 GN=LOC103495198 ...	[more]
A0A5A7SJN1	1.5e-40	92.94	Diphthamide biosynthesis protein 3-like OS=Cucumis melo var. makuwa OX=1194695 G...	[more]
A0A6J1EZW6	4.3e-40	92.94	diphthamide biosynthesis protein 3-like OS=Cucurbita moschata OX=3662 GN=LOC1114...	[more]

BLAST of CmaCh19G006370 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_022972367.1	7.7e-44	100.00	diphthamide biosynthesis protein 3-like [Cucurbita maxima]	[more]
XP_038887330.1	5.5e-42	96.47	diphthamide biosynthesis protein 3-like [Benincasa hispida] >XP_038887331.1 diph...	[more]
XP_022136247.1	1.2e-41	94.12	diphthamide biosynthesis protein 3-like [Momordica charantia]	[more]
XP_008454889.1	3.0e-40	92.94	PREDICTED: diphthamide biosynthesis protein 3-like [Cucumis melo] >XP_008454890....	[more]
XP_022931585.1	8.8e-40	92.94	diphthamide biosynthesis protein 3-like [Cucurbita moschata]	[more]

BLAST of CmaCh19G006370 vs. TAIR 10


Match Name	E-value	Identity	Description
AT2G15910.2	7.0e-35	77.65	CSL zinc finger domain-containing protein	[more]
AT2G15910.1	1.0e-33	78.05	CSL zinc finger domain-containing protein	[more]

InterPro

Analysis Name: InterPro Annotations of Cucurbita maxima (Rimu) v1.1
Date Performed: 2021-10-25


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR007872	DPH-type metal-binding domain	PFAM	PF05207	zf-CSL	coord: 4..58 e-value: 4.6E-22 score: 77.5
IPR007872	DPH-type metal-binding domain	PROSITE	PS51074	DPH_MB	coord: 2..58 score: 23.350922
IPR036671	DPH-type metal-binding domain superfamily	GENE3D	3.10.660.10	DPH Zinc finger	coord: 1..82 e-value: 1.6E-29 score: 103.5
IPR036671	DPH-type metal-binding domain superfamily	SUPERFAMILY	144217	CSL zinc finger	coord: 2..72
IPR044248	Diphthamide biosynthesis protein 3/4-like	PANTHER	PTHR21454	DPH3 HOMOLOG-RELATED	coord: 2..72
None	No IPR available	PANTHER	PTHR21454:SF2	DPH3 HOMOLOG	coord: 2..72

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
CmaCh19G006370.1	CmaCh19G006370.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine
biological_process	GO:0002098	tRNA wobble uridine modification
cellular_component	GO:0005829	cytosol
cellular_component	GO:0005634	nucleus
molecular_function	GO:0046872	metal ion binding