Chy12G207210 (gene) Cucumber (hystrix) v1

Overview


Name	Chy12G207210
Type	gene
Organism	Cucumis hystrix (Cucumber (hystrix) v1)
Description	Mitogen-activated protein kinase
Location	chrH12: 1329285 .. 1329780 (+)
RNA-Seq Expression	Chy12G207210
Synteny	Chy12G207210

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDSpolypeptide

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGACGAAAGGAAGAAAGCCGTTGAAAAACGAAAAACGAACTTTGACCGTCGATCAAAGGCGGCGGAAATCTAAACCGTCCGATCTTCCGTCAGAAGCGCGTGACTTATTTTTCTCCCGCGCCCGAGCCTTCGTTTCCCTTTCCTCGCATTTACTCTTCACTCTCTCTCCATTTCCCCCTTTGACAATTCTTATTTATTGATCCAAATTCTTAAATTCTTCTTCAGACACTTGGTCTTGGTCTTCATCTTCATTCTGGGGTTTCGTTTTCTTGTCTCATAATCGGAGAATTTGATTCAGAAGGCGTTTCTGAGCAAGGGATTTCGAAGAATATGGCTGATGTTGGTCAGAACAACCCTGCTGATTTTCCAGCTCTCCCAACCCATGGTGGCCAATACGTTCAGTATAACATTTTTGGGAATCCCTTCGAAATCACCTCCAAATATCGTCCTCCGATTATGCCTATTGGTCGCGGCGCATACGGAATCGTTTGGTAA

mRNA sequence

ATGACGAAAGGAAGAAAGCCGTTGAAAAACGAAAAACGAACTTTGACCGTCGATCAAAGGCGGCGGAAATCTAAACCGTCCGATCTTCCGTCAGAAGCGCGTGACTTATTTTTCTCCCGCGCCCGAGCCTTCACACTTGGTCTTGGTCTTCATCTTCATTCTGGGGTTTCGTTTTCTTGTCTCATAATCGGAGAATTTGATTCAGAAGGCGTTTCTGAGCAAGGGATTTCGAAGAATATGGCTGATGTTGGTCAGAACAACCCTGCTGATTTTCCAGCTCTCCCAACCCATGGTGGCCAATACGTTCAGTATAACATTTTTGGGAATCCCTTCGAAATCACCTCCAAATATCGTCCTCCGATTATGCCTATTGGTCGCGGCGCATACGGAATCGTTTGGTAA

Coding sequence (CDS)

ATGACGAAAGGAAGAAAGCCGTTGAAAAACGAAAAACGAACTTTGACCGTCGATCAAAGGCGGCGGAAATCTAAACCGTCCGATCTTCCGTCAGAAGCGCGTGACTTATTTTTCTCCCGCGCCCGAGCCTTCACACTTGGTCTTGGTCTTCATCTTCATTCTGGGGTTTCGTTTTCTTGTCTCATAATCGGAGAATTTGATTCAGAAGGCGTTTCTGAGCAAGGGATTTCGAAGAATATGGCTGATGTTGGTCAGAACAACCCTGCTGATTTTCCAGCTCTCCCAACCCATGGTGGCCAATACGTTCAGTATAACATTTTTGGGAATCCCTTCGAAATCACCTCCAAATATCGTCCTCCGATTATGCCTATTGGTCGCGGCGCATACGGAATCGTTTGGTAA

Protein sequence

MTKGRKPLKNEKRTLTVDQRRRKSKPSDLPSEARDLFFSRARAFTLGLGLHLHSGVSFSCLIIGEFDSEGVSEQGISKNMADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIVW*

Homology

[Close]

BLAST of Chy12G207210 vs. ExPASy Swiss-Prot
Match: Q39023 (Mitogen-activated protein kinase 3 OS=Arabidopsis thaliana OX=3702 GN=MPK3 PE=1 SV=2)

HSP 1 Score: 82.0 bits (201), Expect = 5.5e-15
Identity = 35/51 (68.63%), Postives = 42/51 (82.35%), Query Frame = 0


Query: 82  DVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 133
           + G     DFPA+ THGGQ++ Y+IFG+ FEITSKYRPPI+PIGRGAYGIV
Sbjct: 2   NTGGGQYTDFPAVETHGGQFISYDIFGSLFEITSKYRPPIIPIGRGAYGIV 52

[Close]

BLAST of Chy12G207210 vs. ExPASy Swiss-Prot
Match: Q06060 (Mitogen-activated protein kinase homolog D5 OS=Pisum sativum OX=3888 PE=2 SV=1)

HSP 1 Score: 77.4 bits (189), Expect = 1.4e-13
Identity = 31/43 (72.09%), Postives = 39/43 (90.70%), Query Frame = 0


Query: 90  DFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 133
           + PA  +HGG+++QYNIFGN FE+T+KYRPPIMPIG+GAYGIV
Sbjct: 34  NIPATLSHGGRFIQYNIFGNIFEVTAKYRPPIMPIGKGAYGIV 76

[Close]

BLAST of Chy12G207210 vs. ExPASy Swiss-Prot
Match: Q07176 (Mitogen-activated protein kinase homolog MMK1 OS=Medicago sativa OX=3879 GN=MMK1 PE=1 SV=1)

HSP 1 Score: 77.0 bits (188), Expect = 1.8e-13
Identity = 30/43 (69.77%), Postives = 40/43 (93.02%), Query Frame = 0


Query: 90  DFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 133
           + PA+ +HGG+++QYNIFGN FE+T+KY+PPIMPIG+GAYGIV
Sbjct: 27  NIPAVLSHGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIV 69

[Close]

BLAST of Chy12G207210 vs. ExPASy Swiss-Prot
Match: Q39026 (Mitogen-activated protein kinase 6 OS=Arabidopsis thaliana OX=3702 GN=MPK6 PE=1 SV=1)

HSP 1 Score: 76.3 bits (186), Expect = 3.0e-13
Identity = 30/43 (69.77%), Postives = 39/43 (90.70%), Query Frame = 0


Query: 90  DFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 133
           + PA  +HGG+++QYNIFGN FE+T+KY+PPIMPIG+GAYGIV
Sbjct: 35  NIPATLSHGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIV 77

[Close]

BLAST of Chy12G207210 vs. ExPASy Swiss-Prot
Match: Q40532 (Mitogen-activated protein kinase homolog NTF4 OS=Nicotiana tabacum OX=4097 GN=NTF4 PE=2 SV=1)

HSP 1 Score: 76.3 bits (186), Expect = 3.0e-13
Identity = 30/43 (69.77%), Postives = 39/43 (90.70%), Query Frame = 0


Query: 90  DFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 133
           + PA  +HGG+++QYNIFGN FE+T+KY+PPIMPIG+GAYGIV
Sbjct: 32  NIPATLSHGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIV 74

[Close]

BLAST of Chy12G207210 vs. ExPASy TrEMBL
Match: A0A5A7T8I9 (Mitogen-activated protein kinase OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold918G00050 PE=3 SV=1)

HSP 1 Score: 175.3 bits (443), Expect = 1.8e-40
Identity = 92/131 (70.23%), Postives = 95/131 (72.52%), Query Frame = 0


Query: 1   MTKGRKPLKNEKRTLTVDQRRRKSKPSDLPSEARDLFFSRARAFTLGLGLHLHSGVSFSC 60
           MTKGRKPLKNEKRTLTVDQRRRKSKPSDLPSEA                           
Sbjct: 1   MTKGRKPLKNEKRTLTVDQRRRKSKPSDLPSEA--------------------------- 60

Query: 61  LIIGEFDSEGVSEQGISKNMADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPP 120
                   +GVSEQ +S+NMADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPP
Sbjct: 61  --------QGVSEQRVSRNMADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPP 96

Query: 121 IMPIGRGAYGI 132
           IMPIGRGAYGI
Sbjct: 121 IMPIGRGAYGI 96

[Close]

BLAST of Chy12G207210 vs. ExPASy TrEMBL
Match: A0A5D3BXD1 (Mitogen-activated protein kinase OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold968G00210 PE=3 SV=1)

HSP 1 Score: 132.5 bits (332), Expect = 1.3e-27
Identity = 59/63 (93.65%), Postives = 62/63 (98.41%), Query Frame = 0


Query: 69  EGVSEQGISKNMADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGA 128
           +GVSEQ +S+NMADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGA
Sbjct: 20  QGVSEQRVSRNMADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGA 79

Query: 129 YGI 132
           YGI
Sbjct: 80  YGI 82

[Close]

BLAST of Chy12G207210 vs. ExPASy TrEMBL
Match: Q0R4I2 (Mitogen-activated protein kinase OS=Cucumis sativus OX=3659 GN=TIPK PE=2 SV=1)

HSP 1 Score: 119.4 bits (298), Expect = 1.2e-23
Identity = 53/53 (100.00%), Postives = 53/53 (100.00%), Query Frame = 0


Query: 80  MADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 133
           MADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV
Sbjct: 1   MADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 53

[Close]

BLAST of Chy12G207210 vs. ExPASy TrEMBL
Match: F8ULD9 (Mitogen-activated protein kinase OS=Cucumis melo OX=3656 GN=LOC103497219 PE=2 SV=1)

HSP 1 Score: 119.4 bits (298), Expect = 1.2e-23
Identity = 53/53 (100.00%), Postives = 53/53 (100.00%), Query Frame = 0


Query: 80  MADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 133
           MADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV
Sbjct: 1   MADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 53

[Close]

BLAST of Chy12G207210 vs. ExPASy TrEMBL
Match: A0A6J1GAP2 (Mitogen-activated protein kinase OS=Cucurbita moschata OX=3662 GN=LOC111452292 PE=3 SV=1)

HSP 1 Score: 113.2 bits (282), Expect = 8.3e-22
Identity = 49/53 (92.45%), Postives = 51/53 (96.23%), Query Frame = 0


Query: 80  MADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 133
           MADVGQNN  DFPA+PTHGGQYVQYNIFGNPFEITSKYRPPIMP+GRGAYGIV
Sbjct: 1   MADVGQNNTGDFPAVPTHGGQYVQYNIFGNPFEITSKYRPPIMPVGRGAYGIV 53

[Close]

BLAST of Chy12G207210 vs. NCBI nr
Match: KAA0037795.1 (mitogen-activated protein kinase 3 [Cucumis melo var. makuwa])

HSP 1 Score: 176 bits (445), Expect = 1.40e-50
Identity = 92/131 (70.23%), Postives = 95/131 (72.52%), Query Frame = 0


Query: 1   MTKGRKPLKNEKRTLTVDQRRRKSKPSDLPSEARDLFFSRARAFTLGLGLHLHSGVSFSC 60
           MTKGRKPLKNEKRTLTVDQRRRKSKPSDLPSEA                           
Sbjct: 1   MTKGRKPLKNEKRTLTVDQRRRKSKPSDLPSEA--------------------------- 60

Query: 61  LIIGEFDSEGVSEQGISKNMADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPP 120
                   +GVSEQ +S+NMADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPP
Sbjct: 61  --------QGVSEQRVSRNMADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPP 96

Query: 121 IMPIGRGAYGI 131
           IMPIGRGAYGI
Sbjct: 121 IMPIGRGAYGI 96

[Close]

BLAST of Chy12G207210 vs. NCBI nr
Match: TYK02886.1 (mitogen-activated protein kinase 3 [Cucumis melo var. makuwa])

HSP 1 Score: 133 bits (334), Expect = 2.77e-34
Identity = 59/63 (93.65%), Postives = 62/63 (98.41%), Query Frame = 0


Query: 69  EGVSEQGISKNMADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGA 128
           +GVSEQ +S+NMADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGA
Sbjct: 20  QGVSEQRVSRNMADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGA 79

Query: 129 YGI 131
           YGI
Sbjct: 80  YGI 82

[Close]

BLAST of Chy12G207210 vs. NCBI nr
Match: KAG7036887.1 (Mitogen-activated protein kinase 3, partial [Cucurbita argyrosperma subsp. argyrosperma])

HSP 1 Score: 117 bits (294), Expect = 8.10e-30
Identity = 50/54 (92.59%), Postives = 52/54 (96.30%), Query Frame = 0


Query: 80  MADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIVW 133
           MADVGQNN  DFPA+PTHGGQYVQYNIFGNPFEITSKYRPPIMP+GRGAYGIVW
Sbjct: 1   MADVGQNNTGDFPAVPTHGGQYVQYNIFGNPFEITSKYRPPIMPVGRGAYGIVW 54

[Close]

BLAST of Chy12G207210 vs. NCBI nr
Match: NP_001267653.1 (mitogen-activated protein kinase 3-like [Cucumis sativus] >AAZ57337.1 Trichoderma-induced protein kinase [Cucumis sativus] >ABG89857.1 NO3-stress-induced mitogen activated protein kinase [Cucumis sativus] >KGN65657.1 hypothetical protein Csa_020125 [Cucumis sativus])

HSP 1 Score: 119 bits (299), Expect = 2.53e-29
Identity = 53/53 (100.00%), Postives = 53/53 (100.00%), Query Frame = 0


Query: 80  MADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 132
           MADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV
Sbjct: 1   MADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 53

[Close]

BLAST of Chy12G207210 vs. NCBI nr
Match: NP_001284376.1 (mitogen-activated protein kinase 3 [Cucumis melo] >AEG89601.1 mitogen-activated protein [Cucumis melo])

HSP 1 Score: 119 bits (299), Expect = 2.53e-29
Identity = 53/53 (100.00%), Postives = 53/53 (100.00%), Query Frame = 0


Query: 80  MADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 132
           MADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV
Sbjct: 1   MADVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 53

[Close]

BLAST of Chy12G207210 vs. TAIR 10
Match: AT3G45640.1 (mitogen-activated protein kinase 3 )

HSP 1 Score: 82.0 bits (201), Expect = 3.9e-16
Identity = 35/51 (68.63%), Postives = 42/51 (82.35%), Query Frame = 0


Query: 82  DVGQNNPADFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 133
           + G     DFPA+ THGGQ++ Y+IFG+ FEITSKYRPPI+PIGRGAYGIV
Sbjct: 2   NTGGGQYTDFPAVETHGGQFISYDIFGSLFEITSKYRPPIIPIGRGAYGIV 52

[Close]

BLAST of Chy12G207210 vs. TAIR 10
Match: AT2G43790.1 (MAP kinase 6 )

HSP 1 Score: 76.3 bits (186), Expect = 2.2e-14
Identity = 30/43 (69.77%), Postives = 39/43 (90.70%), Query Frame = 0


Query: 90  DFPALPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 133
           + PA  +HGG+++QYNIFGN FE+T+KY+PPIMPIG+GAYGIV
Sbjct: 35  NIPATLSHGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIV 77

[Close]

BLAST of Chy12G207210 vs. TAIR 10
Match: AT4G01370.1 (MAP kinase 4 )

HSP 1 Score: 68.6 bits (166), Expect = 4.5e-12
Identity = 27/37 (72.97%), Postives = 32/37 (86.49%), Query Frame = 0


Query: 96  THGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 133
           THGG YVQYN++GN FE++ KY PP+ PIGRGAYGIV
Sbjct: 21  THGGSYVQYNVYGNLFEVSRKYVPPLRPIGRGAYGIV 57

[Close]

BLAST of Chy12G207210 vs. TAIR 10
Match: AT2G46070.1 (mitogen-activated protein kinase 12 )

HSP 1 Score: 67.0 bits (162), Expect = 1.3e-11
Identity = 27/39 (69.23%), Postives = 33/39 (84.62%), Query Frame = 0


Query: 94  LPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 133
           +PTHGG+YVQYN++G  FE++ KY PPI PIGRGA GIV
Sbjct: 17  VPTHGGRYVQYNVYGQLFEVSRKYVPPIRPIGRGACGIV 55

[Close]

BLAST of Chy12G207210 vs. TAIR 10
Match: AT2G46070.2 (mitogen-activated protein kinase 12 )

HSP 1 Score: 67.0 bits (162), Expect = 1.3e-11
Identity = 27/39 (69.23%), Postives = 33/39 (84.62%), Query Frame = 0


Query: 94  LPTHGGQYVQYNIFGNPFEITSKYRPPIMPIGRGAYGIV 133
           +PTHGG+YVQYN++G  FE++ KY PPI PIGRGA GIV
Sbjct: 17  VPTHGGRYVQYNVYGQLFEVSRKYVPPIRPIGRGACGIV 55

The following BLAST results are available for this feature:

BLAST of Chy12G207210 vs. ExPASy Swiss-Prot


Match Name	E-value	Identity	Description
Q39023	5.5e-15	68.63	Mitogen-activated protein kinase 3 OS=Arabidopsis thaliana OX=3702 GN=MPK3 PE=1 ...	[more]
Q06060	1.4e-13	72.09	Mitogen-activated protein kinase homolog D5 OS=Pisum sativum OX=3888 PE=2 SV=1	[more]
Q07176	1.8e-13	69.77	Mitogen-activated protein kinase homolog MMK1 OS=Medicago sativa OX=3879 GN=MMK1...	[more]
Q39026	3.0e-13	69.77	Mitogen-activated protein kinase 6 OS=Arabidopsis thaliana OX=3702 GN=MPK6 PE=1 ...	[more]
Q40532	3.0e-13	69.77	Mitogen-activated protein kinase homolog NTF4 OS=Nicotiana tabacum OX=4097 GN=NT...	[more]

BLAST of Chy12G207210 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A5A7T8I9	1.8e-40	70.23	Mitogen-activated protein kinase OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27...	[more]
A0A5D3BXD1	1.3e-27	93.65	Mitogen-activated protein kinase OS=Cucumis melo var. makuwa OX=1194695 GN=E5676...	[more]
Q0R4I2	1.2e-23	100.00	Mitogen-activated protein kinase OS=Cucumis sativus OX=3659 GN=TIPK PE=2 SV=1	[more]
F8ULD9	1.2e-23	100.00	Mitogen-activated protein kinase OS=Cucumis melo OX=3656 GN=LOC103497219 PE=2 SV...	[more]
A0A6J1GAP2	8.3e-22	92.45	Mitogen-activated protein kinase OS=Cucurbita moschata OX=3662 GN=LOC111452292 P...	[more]

BLAST of Chy12G207210 vs. NCBI nr


Match Name	E-value	Identity	Description
KAA0037795.1	1.40e-50	70.23	mitogen-activated protein kinase 3 [Cucumis melo var. makuwa]	[more]
TYK02886.1	2.77e-34	93.65	mitogen-activated protein kinase 3 [Cucumis melo var. makuwa]	[more]
KAG7036887.1	8.10e-30	92.59	Mitogen-activated protein kinase 3, partial [Cucurbita argyrosperma subsp. argyr...	[more]
NP_001267653.1	2.53e-29	100.00	mitogen-activated protein kinase 3-like [Cucumis sativus] >AAZ57337.1 Trichoderm...	[more]
NP_001284376.1	2.53e-29	100.00	mitogen-activated protein kinase 3 [Cucumis melo] >AEG89601.1 mitogen-activated ...	[more]

BLAST of Chy12G207210 vs. TAIR 10


Match Name	E-value	Identity	Description
AT3G45640.1	3.9e-16	68.63	mitogen-activated protein kinase 3	[more]
AT2G43790.1	2.2e-14	69.77	MAP kinase 6	[more]
AT4G01370.1	4.5e-12	72.97	MAP kinase 4	[more]
AT2G46070.1	1.3e-11	69.23	mitogen-activated protein kinase 12	[more]
AT2G46070.2	1.3e-11	69.23	mitogen-activated protein kinase 12	[more]

InterPro

Analysis Name: InterPro Annotations of Cucumber (hystrix) v1
Date Performed: 2021-10-25


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	GENE3D	3.30.200.20	Phosphorylase Kinase; domain 1	coord: 95..133 e-value: 2.6E-9 score: 38.6
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..30

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
Chy12G207210.1	Chy12G207210.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0042742	defense response to bacterium
biological_process	GO:0050832	defense response to fungus
biological_process	GO:0000165	MAPK cascade
biological_process	GO:1901002	positive regulation of response to salt stress
biological_process	GO:0006468	protein phosphorylation
biological_process	GO:0009409	response to cold
biological_process	GO:0009414	response to water deprivation
cellular_component	GO:0005737	cytoplasm
cellular_component	GO:0005634	nucleus
molecular_function	GO:0005524	ATP binding
molecular_function	GO:0004707	MAP kinase activity
molecular_function	GO:0004712	protein serine/threonine/tyrosine kinase activity