SwissProt blast output of UN78422
BLASTX 7.6.2
Query= UN78422 /QuerySize=1560
(1559 letters)
Database: Uniprot/SwissProt;
537,505 sequences; 190,795,139 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9T0K7|HIBC6_ARATH 3-hydroxyisobutyryl-CoA hydrolase-like pro... 518 7e-146
sp|Q9LK08|HIBC7_ARATH 3-hydroxyisobutyryl-CoA hydrolase-like pro... 505 6e-142
sp|A2VDC2|HIBCH_XENLA 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 161 2e-038
sp|Q5ZJ60|HIBCH_CHICK 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 159 5e-038
sp|Q55GS6|HIBCH_DICDI 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 159 8e-038
sp|Q28FR6|HIBCH_XENTR 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 156 5e-037
sp|Q9LKJ1|HIBC1_ARATH 3-hydroxyisobutyryl-CoA hydrolase 1 OS=Ara... 154 2e-036
sp|Q5XIE6|HIBCH_RAT 3-hydroxyisobutyryl-CoA hydrolase, mitochond... 154 2e-036
sp|Q2HJ73|HIBCH_BOVIN 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 153 4e-036
sp|Q6NVY1|HIBCH_HUMAN 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 153 4e-036
sp|Q6NMB0|HIBC3_ARATH Probable 3-hydroxyisobutyryl-CoA hydrolase... 153 5e-036
sp|Q8QZS1|HIBCH_MOUSE 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 153 5e-036
sp|Q58EB4|HIBCH_DANRE 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 149 7e-035
sp|Q1PEY5|HIBC2_ARATH Probable 3-hydroxyisobutyryl-CoA hydrolase... 146 6e-034
sp|P28817|HIBCH_YEAST 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 137 3e-031
sp|O74802|HIBCH_SCHPO 3-hydroxyisobutyryl-CoA hydrolase, mitocho... 128 1e-028
sp|Q8RXN4|HIBC5_ARATH 3-hydroxyisobutyryl-CoA hydrolase-like pro... 118 2e-025
>sp|Q9T0K7|HIBC6_ARATH 3-hydroxyisobutyryl-CoA hydrolase-like protein 3,
mitochondrial OS=Arabidopsis thaliana GN=At4g13360 PE=1 SV=2
Length = 421
Score = 518 bits (1332), Expect = 7e-146
Identities = 260/386 (67%), Positives = 309/386 (80%), Gaps = 13/386 (3%)
Frame = -2
Query: 1423 RKLSVMASG---EFVKGNVYPNGLALLTLDRPKALNAMNLDMDKKYRRYLDEWEVDPKVK 1253
RK S MA +FVKGNV+PNG+AL+TLDR KALNAMNLDMD KY+ +LDEWE DP+VK
Sbjct: 36 RKFSAMAGAGVDDFVKGNVFPNGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVK 95
Query: 1252 CVLVEGSTPRGFSAGGDVK----QISTLKQLSEIIEVFTSEYSLICKISEYKKPYISFMD 1085
CV+VEGST R F AG D+K +I K + +VFT+EY+LIC I+ YKKPYIS MD
Sbjct: 96 CVIVEGSTSRAFCAGMDIKGVAAEIQKDKNTPLVQKVFTAEYTLICAIAAYKKPYISLMD 155
Query: 1084 GITMGFGIGLSGHGRYRVITERTVLAMPENAIGLFPDVGFAYIAARSPGGGSVGAYLGMT 905
GITMGFG+GLSGHGRYRVITERTVLAMPEN IGLFPDVGF+YIAA SPGGGSVGAYLG+T
Sbjct: 156 GITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLT 215
Query: 904 GNRVSTPADALYVGLGNYFVPSGNLSSIKDSLLLTTFFEDPHREVQATLEKYSSNPESEP 725
G R+S P+DAL+VGLG ++VPS L+S+K+++L EDP++++QATL KYSSNPESE
Sbjct: 216 GKRISAPSDALFVGLGTHYVPSEKLASLKEAILSANLSEDPNQDIQATLSKYSSNPESEA 275
Query: 724 RLKLLLPHIVSTFGSNKSVKEIMDELEKYQ------VAEWAKDALSGLKRGAPFSLSLTQ 563
LK LLPHI S F SNKS+KE ++EL+KYQ V EWA +AL GL++GAPFSL LTQ
Sbjct: 276 HLKSLLPHIESAFSSNKSIKETIEELKKYQQSTESSVVEWANEALKGLEKGAPFSLYLTQ 335
Query: 562 HYFSRVASACGDKKSELSTLNGVMKTEYRIALRTTLRSDFMEGVRAVLVDKDQNPKWNPS 383
YFS VA A ++EL+TLNGVMKTEYRIALR+ LR DF EGVRAVL+DKDQNPKWNP+
Sbjct: 336 KYFSNVACAKSKPENELATLNGVMKTEYRIALRSALRGDFAEGVRAVLIDKDQNPKWNPT 395
Query: 382 SLEEVKATEVESLFEPLDSEADELGV 305
S+EEV EVE+LF+PL E +EL V
Sbjct: 396 SIEEVDENEVEALFKPLSPEVEELKV 421
>sp|Q9LK08|HIBC7_ARATH 3-hydroxyisobutyryl-CoA hydrolase-like protein 4,
mitochondrial OS=Arabidopsis thaliana GN=At3g24360 PE=2 SV=1
Length = 418
Score = 505 bits (1298), Expect = 6e-142
Identities = 256/385 (66%), Positives = 307/385 (79%), Gaps = 12/385 (3%)
Frame = -2
Query: 1423 RKLSVMASG--EFVKGNVYPNGLALLTLDRPKALNAMNLDMDKKYRRYLDEWEVDPKVKC 1250
RK SVMASG EFVKGNVYPNG+AL+TLDRPKALNAMNL+MD KY+ LDEWE DP VKC
Sbjct: 34 RKFSVMASGSDEFVKGNVYPNGVALITLDRPKALNAMNLEMDLKYKSLLDEWEYDPGVKC 93
Query: 1249 VLVEGSTPRGFSAGGDVK----QISTLKQLSEIIEVFTSEYSLICKISEYKKPYISFMDG 1082
V+VEGST R F AG D+K +I K S + +VFT+EYSLICKI+ Y+KPYIS MDG
Sbjct: 94 VVVEGSTSRAFCAGMDIKGVVAEILMDKNTSLVQKVFTAEYSLICKIAGYRKPYISLMDG 153
Query: 1081 ITMGFGIGLSGHGRYRVITERTVLAMPENAIGLFPDVGFAYIAARSPGGGSVGAYLGMTG 902
ITMGFG+GLSGHGRYRVITERTVLAMPEN IGLFPDVGF+YIAA SPG GSVGAYLGMTG
Sbjct: 154 ITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGEGSVGAYLGMTG 213
Query: 901 NRVSTPADALYVGLGNYFVPSGNLSSIKDSLLLTTFFEDPHREVQATLEKYSSNPESEPR 722
R+STP+DAL+VGLG ++VPSG L S+++++L +DP + +QATL YSS+PE+E
Sbjct: 214 RRISTPSDALFVGLGTHYVPSGKLGSLREAILSADLSKDPQQHIQATLSNYSSDPETESH 273
Query: 721 LKLLLPHIVSTFGSNKSVKEIMDELEKYQ------VAEWAKDALSGLKRGAPFSLSLTQH 560
L++LLP I S F +KSVKE ++EL+K+Q VAEWA +A+ G+++GAPFSL LT
Sbjct: 274 LQMLLPQIESAFSVSKSVKETIEELKKFQQSSEASVAEWANEAVQGIEKGAPFSLYLTHK 333
Query: 559 YFSRVASACGDKKSELSTLNGVMKTEYRIALRTTLRSDFMEGVRAVLVDKDQNPKWNPSS 380
YFS+VA A G + ++TLNGVM TEYRIALR+ LRSDF EGVRAVL DKDQNPKW P+S
Sbjct: 334 YFSKVACAKGKTNNAMATLNGVMITEYRIALRSALRSDFTEGVRAVLTDKDQNPKWKPAS 393
Query: 379 LEEVKATEVESLFEPLDSEADELGV 305
L+EV TEV++LF PL E +EL V
Sbjct: 394 LDEVDETEVDALFMPLSPEFEELNV 418
>sp|A2VDC2|HIBCH_XENLA 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
OS=Xenopus laevis GN=hibch PE=2 SV=1
Length = 385
Score = 161 bits (405), Expect = 2e-038
Identities = 102/279 (36%), Positives = 157/279 (56%), Gaps = 13/279 (4%)
Frame = -2
Query: 1357 LLTLDRPKALNAMNLDMDKKYRRYLDEWEVDPKVKCVLVEGSTPRGFSAGGDVKQISTLK 1178
++TL+RPKALNA+NL M ++ L WE DP+ V+++G+ + F AGGD++ ++
Sbjct: 47 VITLNRPKALNALNLGMIRQIYPQLKLWEEDPETYLVIIKGAGGKAFCAGGDIRAVTDAG 106
Query: 1177 QLSEII--EVFTSEYSLICKISEYKKPYISFMDGITMGFGIGLSGHGRYRVITERTVLAM 1004
++ + + + F EY L I KKPY++ +DGITMG G+GLS HG +RV +E+T+ AM
Sbjct: 107 KVGDRLAQDFFREEYILNNAIGTCKKPYVAVIDGITMGGGVGLSVHGHFRVASEKTLFAM 166
Query: 1003 PENAIGLFPDVGFAYIAARSPGGGSVGAYLGMTGNRVSTPADALYVGLGNYFVPSGNLSS 824
PE AIGLFPDVG Y R G +G YL +TG R+ +D G+ +FV S LSS
Sbjct: 167 PETAIGLFPDVGGGYFLPRLT--GKLGLYLALTGFRLK-GSDVQKAGIATHFVESEKLSS 223
Query: 823 IKDSLLLTTFFEDPHRE----VQATLEKYSSNPESEPRLKLLLPHIVSTFGSNKSVKEIM 656
++ L+ + P +E V + +K S + +P + +++ S +V+EIM
Sbjct: 224 LEQDLVA---MKSPSKENVADVLDSYQKKSYAAQDKPFVLAENMDKINSLFSGNTVEEIM 280
Query: 655 DELEKYQVAEWAKDALSGLKRGAPFSLSLTQHYFSRVAS 539
+ L K + +A L L +P SL +T AS
Sbjct: 281 ENL-KCDGSSFAMKQLQTLSTMSPTSLKITFRQLKEGAS 318
>sp|Q5ZJ60|HIBCH_CHICK 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
OS=Gallus gallus GN=HIBCH PE=2 SV=1
Length = 385
Score = 159 bits (402), Expect = 5e-038
Identities = 100/274 (36%), Positives = 152/274 (55%), Gaps = 15/274 (5%)
Frame = -2
Query: 1366 GLALLTLDRPKALNAMNLDMDKKYRRYLDEWEVDPKVKCVLVEGSTPRGFSAGGDVKQIS 1187
G ++TL+RPK LNA++ M ++ + WE DP+ ++++G+ + F AGGDV+ I+
Sbjct: 44 GAGIITLNRPKVLNALSFKMIQQIYPQIKAWEQDPETFLIIIKGTGEKAFCAGGDVRAIA 103
Query: 1186 TLKQLSEII--EVFTSEYSLICKISEYKKPYISFMDGITMGFGIGLSGHGRYRVITERTV 1013
+ + + + F EY L I KKPY++ +DGITMG G+GLS HG +RV TE+TV
Sbjct: 104 DAGKAGDTMTRDYFREEYRLDNAIGTCKKPYVALIDGITMGGGVGLSVHGHFRVATEKTV 163
Query: 1012 LAMPENAIGLFPDVGFAYIAARSPGGGSVGAYLGMTGNRVSTPADALYVGLGNYFVPSGN 833
AMPE AIGLFPDVG Y R G +G L +TG R+ D L G+ +FV SG
Sbjct: 164 FAMPETAIGLFPDVGGGYFLPRL--SGKIGHLLALTGFRLK-GRDVLKAGIATHFVESGK 220
Query: 832 LSSIKDSLLLTTFFEDPHRE-VQATLEKYSSNPESEPRLKLLL----PHIVSTFGSNKSV 668
L ++ L+ + P +E + L Y + + + +L I S F +N S+
Sbjct: 221 LPELEKDLIA---LKSPSKENIADLLNSYHMQTKIDQEKEFVLDEHMERINSIFSAN-SM 276
Query: 667 KEIMDELEKYQVAEWAKDALSGLKRGAPFSLSLT 566
+EI+ +L K + +A L + + +P SL LT
Sbjct: 277 EEIVQKL-KQDGSPFATKQLEAINKMSPTSLKLT 309
Score = 62 bits (150), Expect = 8e-009
Identities = 29/59 (49%), Positives = 40/59 (67%)
Frame = -2
Query: 508 TLNGVMKTEYRIALRTTLRSDFMEGVRAVLVDKDQNPKWNPSSLEEVKATEVESLFEPL 332
+L V EYR++ DF EGVRAVL+DKDQ+P+W P++LEEV V++ F+PL
Sbjct: 320 SLQDVFTMEYRLSQACMRGHDFYEGVRAVLIDKDQSPRWKPAALEEVSDEFVDNCFKPL 378
>sp|Q55GS6|HIBCH_DICDI 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
OS=Dictyostelium discoideum GN=hibch PE=3 SV=1
Length = 381
Score = 159 bits (400), Expect = 8e-038
Identities = 108/319 (33%), Positives = 164/319 (51%), Gaps = 40/319 (12%)
Frame = -2
Query: 1249 VLVEGSTPRGFSAGGDVKQISTLKQLSEIIE---------VFTSEYSLICKISEYKKPYI 1097
++++G+ + F AGGD++ I KQL+E + F EY L I +
Sbjct: 72 IVMKGAGEKAFCAGGDIRAIYDYKQLNEEQKSKTNDIGDLFFREEYILNNLIGTNPIAQV 131
Query: 1096 SFMDGITMGFGIGLSGHGRYRVITERTVLAMPENAIGLFPDVGFAYIAARSPGGGSVGAY 917
S +G MG GIGLS HG++RV TE TV AMPE IG F DVG +Y R P + G Y
Sbjct: 132 SIYNGFAMGGGIGLSVHGKFRVATENTVFAMPETGIGFFCDVGGSYFLPRLP--NNYGMY 189
Query: 916 LGMTGNRVSTPADALYVGLGNYFVPSGNLSSIK---------DSLLLTTFFEDPHREVQA 764
L +TG+++ + G+ +FV + ++ +++ S + + H + ++
Sbjct: 190 LALTGSKLK-GNNVYLAGVATHFVSNEHIQALEKEIEECENPTSQTINSILTKYHDKSKS 248
Query: 763 TLEKYSSNPESEPRLKLLLPHIVSTFGSNKSVKEIMDELEKYQVAEWAKDALSGLKRGAP 584
T +Y+ N L I FG N SVKEI ++LE + +EWAK L LK +P
Sbjct: 249 TSNEYNDN----------LGDIERIFGKN-SVKEIFEQLELLENSEWAKQTLKTLKSVSP 297
Query: 583 FSLSLTQHYFSRVASACGDKKSELSTLNGVMKTEYRIALRTTLRSDFMEGVRAVLVDKDQ 404
SL + + A +L +L ++ E+RI+ + DF EGVRA+LVDKD+
Sbjct: 298 SSLMVVFEQMKQGA--------KLPSLAKCLEMEFRISQHFLEKPDFFEGVRALLVDKDK 349
Query: 403 NPKWNPSSLEEVKATEVES 347
NPKW P S++++ T V S
Sbjct: 350 NPKWLPPSIDQIDQTLVNS 368
Score = 64 bits (153), Expect = 4e-009
Identities = 29/68 (42%), Positives = 46/68 (67%)
Frame = -2
Query: 520 SELSTLNGVMKTEYRIALRTTLRSDFMEGVRAVLVDKDQNPKWNPSSLEEVKATEVESLF 341
++L +L ++ E+RI+ + DF EGVRA+LVDKD+NPKW P S++++ T V S F
Sbjct: 311 AKLPSLAKCLEMEFRISQHFLEKPDFFEGVRALLVDKDKNPKWLPPSIDQIDQTLVNSYF 370
Query: 340 EPLDSEAD 317
+PL + +
Sbjct: 371 KPLSNNKE 378
>sp|Q28FR6|HIBCH_XENTR 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
OS=Xenopus tropicalis GN=hibch PE=2 SV=1
Length = 385
Score = 156 bits (393), Expect = 5e-037
Identities = 99/270 (36%), Positives = 155/270 (57%), Gaps = 13/270 (4%)
Frame = -2
Query: 1357 LLTLDRPKALNAMNLDMDKKYRRYLDEWEVDPKVKCVLVEGSTPRGFSAGGDVKQISTLK 1178
++TL+RPKALNA+NL M + L WE DP+ V+++G + F AGGD++ ++
Sbjct: 47 VITLNRPKALNALNLGMIRLIYPQLGLWEEDPETYLVIIKGVGGKAFCAGGDIRAVTDAG 106
Query: 1177 QLSEII--EVFTSEYSLICKISEYKKPYISFMDGITMGFGIGLSGHGRYRVITERTVLAM 1004
+ + + + F EY L I YKKPY++ +DGITMG G+GLS HG +RV +E T+ AM
Sbjct: 107 KAGDRLAQDFFREEYILNNAIGTYKKPYVALIDGITMGGGVGLSVHGHFRVASENTLFAM 166
Query: 1003 PENAIGLFPDVGFAYIAARSPGGGSVGAYLGMTGNRVSTPADALYVGLGNYFVPSGNLSS 824
PE AIGLFPDVG Y R P G +G YL +TG R+ +D G+ +FV S + S
Sbjct: 167 PETAIGLFPDVGGGYFLPRLP--GKLGLYLALTGFRLK-GSDVQKAGIATHFVESEKIPS 223
Query: 823 IKDSLLLTTFFEDPHRE-VQATLEKY-SSNPESEPRLKLLLPHI--VSTFGSNKSVKEIM 656
++ L+ + P +E V L+ Y + + ++ + +L H+ +++ S SV+ I+
Sbjct: 224 LEQDLVA---MKCPSKENVADVLDSYHNKSYAAQDKPFVLAEHLDKINSLFSASSVEAII 280
Query: 655 DELEKYQVAEWAKDALSGLKRGAPFSLSLT 566
+ L + + +A L L +P SL +T
Sbjct: 281 ENL-RCDGSSFALKQLQTLSTMSPTSLKIT 309
>sp|Q9LKJ1|HIBC1_ARATH 3-hydroxyisobutyryl-CoA hydrolase 1 OS=Arabidopsis
thaliana GN=CHY1 PE=1 SV=1
Length = 378
Score = 154 bits (389), Expect = 2e-036
Identities = 98/276 (35%), Positives = 154/276 (55%), Gaps = 16/276 (5%)
Frame = -2
Query: 1369 NGLALLTLDRPKALNAMNLDMDKKYRRYLDEWEVDPKVKCVLVEGSTPRGFSAGGDVKQI 1190
+ + +LTL+RPK LNA++ M + + +E DP VK V+++G R F AGGDV +
Sbjct: 17 SSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGH-GRAFCAGGDVAAV 75
Query: 1189 STLKQLSE-----IIEVFTSEYSLICKISEYKKPYISFMDGITMGFGIGLSGHGRYRVIT 1025
++ +++ F+SEY L ++ Y K +S ++GI MG G G+S HGR+R+ T
Sbjct: 76 --VRDINQGNWRLGANYFSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIAT 133
Query: 1024 ERTVLAMPENAIGLFPDVGFAYIAARSPGGGSVGAYLGMTGNRVSTPADALYVGLGNYFV 845
E TV AMPE A+GLFPDVG +Y +R P G G Y+G+TG R+ A+ L GL +FV
Sbjct: 134 ENTVFAMPETALGLFPDVGASYFLSRLP--GFFGEYVGLTGARLD-GAEMLACGLATHFV 190
Query: 844 PSGNLSSIKDSLLLTTFFEDPHREVQATLEKYSSNPESEPRLKLLLPHIVSTFGSNKSVK 665
PS L++++ L DP L+ Y+ +P + + ++ S ++V+
Sbjct: 191 PSTRLTALEADLCRIN-SNDP-TFASTILDAYTQHPRLKQQSAYRRLDVIDRCFSRRTVE 248
Query: 664 EIMDELEKYQVAE---WAKDALSGLKRGAPFSLSLT 566
EI+ LE+ E W + LK+G+P SL ++
Sbjct: 249 EIISALEREATQEADGWISATIQALKKGSPASLKIS 284
>sp|Q5XIE6|HIBCH_RAT 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Rattus
norvegicus GN=Hibch PE=1 SV=2
Length = 385
Score = 154 bits (388), Expect = 2e-036
Identities = 95/271 (35%), Positives = 157/271 (57%), Gaps = 15/271 (5%)
Frame = -2
Query: 1357 LLTLDRPKALNAMNLDMDKKYRRYLDEWEVDPKVKCVLVEGSTPRGFSAGGDVKQISTLK 1178
++TL+RPK LNA++L+M ++ L +WE DP ++++G+ + F AGGD+K +S K
Sbjct: 47 VITLNRPKLLNALSLNMIRQIYPQLKKWERDPDTFLIIIKGAGGKAFCAGGDIKALSEAK 106
Query: 1177 QLSEII--EVFTSEYSLICKISEYKKPYISFMDGITMGFGIGLSGHGRYRVITERTVLAM 1004
+ + + ++F EY L I+ +KPY++ +DGITMG G+GLS HG++RV TER++ AM
Sbjct: 107 KAGQTLSQDLFREEYILNNAIASCQKPYVALIDGITMGGGVGLSVHGQFRVATERSLFAM 166
Query: 1003 PENAIGLFPDVGFAYIAARSPGGGSVGAYLGMTGNRVSTPADALYVGLGNYFVPSGNLSS 824
PE IGLFPDVG Y R G +G +L +TG R+ D G+ +FV S L
Sbjct: 167 PETGIGLFPDVGGGYFLPRLQ--GKLGYFLALTGFRLK-GRDVHRAGIATHFVDSEKLHV 223
Query: 823 IKDSLLLTTFFEDPHRE-VQATLEKYSSNPESEPRLKLL----LPHIVSTFGSNKSVKEI 659
+++ LL + P E V LE Y + + ++ + I S F +N +V++I
Sbjct: 224 LEEELLA---LKSPSAEDVAGVLESYHAKSKMGQDKSIIFEEHMDKINSCFSAN-TVEQI 279
Query: 658 MDELEKYQVAEWAKDALSGLKRGAPFSLSLT 566
++ L + + +A + + + + +P SL +T
Sbjct: 280 LENL-RQDGSPFAMEQIKVINKMSPTSLKIT 309
>sp|Q2HJ73|HIBCH_BOVIN 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Bos
taurus GN=HIBCH PE=2 SV=1
Length = 386
Score = 153 bits (386), Expect = 4e-036
Identities = 92/270 (34%), Positives = 159/270 (58%), Gaps = 13/270 (4%)
Frame = -2
Query: 1357 LLTLDRPKALNAMNLDMDKKYRRYLDEWEVDPKVKCVLVEGSTPRGFSAGGDVKQISTLK 1178
++TL+RP+ LN + L M ++ L +WE DPK ++++G+ + F AGGD++ +S +
Sbjct: 48 VITLNRPRFLNTLTLGMIRQIYAQLKKWEQDPKTFLIIIKGAGEKAFCAGGDIRALSEAR 107
Query: 1177 QLSE--IIEVFTSEYSLICKISEYKKPYISFMDGITMGFGIGLSGHGRYRVITERTVLAM 1004
++ + ++F EY L I +KPYI+ + GITMG G+G+S HG++RV TE++V AM
Sbjct: 108 NTNQKMLQDLFREEYILNNAIDSCQKPYIALIHGITMGGGVGVSVHGQFRVATEKSVFAM 167
Query: 1003 PENAIGLFPDVGFAYIAARSPGGGSVGAYLGMTGNRVSTPADALYVGLGNYFVPSGNLSS 824
PE AIGLFPDVG Y R G +G +L +TG R+ D G+ +FV L
Sbjct: 168 PETAIGLFPDVGGGYFLPRLQ--GKLGYFLALTGFRLK-GRDVYTAGIATHFVDFEKLGM 224
Query: 823 IKDSLLLTTFFEDPHRE-VQATLEKYSSNPESEPRLKLLL-PHI--VSTFGSNKSVKEIM 656
+++ LL + P +E + LE Y + +++ +L H+ ++++ S +V++I+
Sbjct: 225 LEEDLLA---LKSPSKENIADVLETYHAKSKTDQDKPFILEEHMDKINSWFSANTVEQIV 281
Query: 655 DELEKYQVAEWAKDALSGLKRGAPFSLSLT 566
D L++ + +A + L +K+ +P SL +T
Sbjct: 282 DNLQQ-DGSSFALEQLKVIKKMSPTSLKIT 310
>sp|Q6NVY1|HIBCH_HUMAN 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Homo
sapiens GN=HIBCH PE=1 SV=2
Length = 386
Score = 153 bits (386), Expect = 4e-036
Identities = 95/271 (35%), Positives = 157/271 (57%), Gaps = 15/271 (5%)
Frame = -2
Query: 1357 LLTLDRPKALNAMNLDMDKKYRRYLDEWEVDPKVKCVLVEGSTPRGFSAGGDVKQISTLK 1178
++TL+RPK LNA+ L+M ++ L +WE DP+ ++++G+ + F AGGD++ IS +
Sbjct: 48 VITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAE 107
Query: 1177 QLSEIIE--VFTSEYSLICKISEYKKPYISFMDGITMGFGIGLSGHGRYRVITERTVLAM 1004
+ + I F EY L + +KPY++ + GITMG G+GLS HG++RV TE+ + AM
Sbjct: 108 KAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAM 167
Query: 1003 PENAIGLFPDVGFAYIAARSPGGGSVGAYLGMTGNRVSTPADALYVGLGNYFVPSGNLSS 824
PE AIGLFPDVG Y R G +G +L +TG R+ D G+ +FV S L+
Sbjct: 168 PETAIGLFPDVGGGYFLPRLQ--GKLGYFLALTGFRLK-GRDVYRAGIATHFVDSEKLAM 224
Query: 823 IKDSLLLTTFFEDPHRE-VQATLEKYSSNPESEPRLKLLLPH----IVSTFGSNKSVKEI 659
+++ LL + P +E + + LE Y + + + +L I S F +N +V+EI
Sbjct: 225 LEEDLLA---LKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSAN-TVEEI 280
Query: 658 MDELEKYQVAEWAKDALSGLKRGAPFSLSLT 566
++ L++ + +A + L + + +P SL +T
Sbjct: 281 IENLQQ-DGSSFALEQLKVINKMSPTSLKIT 310
Score = 60 bits (145), Expect = 3e-008
Identities = 29/61 (47%), Positives = 40/61 (65%)
Frame = -2
Query: 508 TLNGVMKTEYRIALRTTLRSDFMEGVRAVLVDKDQNPKWNPSSLEEVKATEVESLFEPLD 329
TL V+ EYR++ DF EGVRAVL+DKDQ+PKW P+ L+EV ++ + F+ L
Sbjct: 321 TLQEVLTMEYRLSQACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSLG 380
Query: 328 S 326
S
Sbjct: 381 S 381
>sp|Q6NMB0|HIBC3_ARATH Probable 3-hydroxyisobutyryl-CoA hydrolase 3
OS=Arabidopsis thaliana GN=At2g30660 PE=2 SV=1
Length = 378
Score = 153 bits (385), Expect = 5e-036
Identities = 94/274 (34%), Positives = 154/274 (56%), Gaps = 12/274 (4%)
Frame = -2
Query: 1369 NGLALLTLDRPKALNAMNLDMDKKYRRYLDEWEVDPKVKCVLVEGSTPRGFSAGGDVKQI 1190
+ + +LTL+RPK LNA+ +M + + +E DP VK V+++G R F AGGDV +
Sbjct: 13 SSVRILTLNRPKQLNALCFNMISRLLQLFRAYEEDPSVKLVILKGQ-GRAFCAGGDVPPV 71
Query: 1189 STLKQLSEI---IEVFTSEYSLICKISEYKKPYISFMDGITMGFGIGLSGHGRYRVITER 1019
+ + F +Y+L ++ Y KP +S ++GI MG G G+S HGR+R+ TE
Sbjct: 72 VQNMVQGKWRLGADFFRDQYTLNYVMATYSKPQVSILNGIVMGAGAGVSIHGRFRIATEN 131
Query: 1018 TVLAMPENAIGLFPDVGFAYIAARSPGGGSVGAYLGMTGNRVSTPADALYVGLGNYFVPS 839
TV AMPE ++GLFPDVG +Y +R P G G Y+G+TG R+ A+ L GL +FVPS
Sbjct: 132 TVFAMPETSLGLFPDVGASYFLSRLP--GFFGEYVGLTGARLD-GAELLACGLATHFVPS 188
Query: 838 GNLSSIKDSLLLTTFFEDPHREVQATLEKYSSNPESEPRLKLLLPHIVSTFGSNKSVKEI 659
L++++ L DP V L+ Y+ +P + + ++ S ++++EI
Sbjct: 189 TRLTALETD-LCKVGSSDP-SFVSTILDAYTQHPHLKQKSAYHRLDVIDRCFSKRTMEEI 246
Query: 658 MDELEK---YQVAEWAKDALSGLKRGAPFSLSLT 566
+ LE+ ++ +W+ + LK+ +P SL ++
Sbjct: 247 ISALERETTQELDDWSLTTIRALKKSSPSSLKIS 280
>sp|Q8QZS1|HIBCH_MOUSE 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Mus
musculus GN=Hibch PE=1 SV=1
Length = 385
Score = 153 bits (385), Expect = 5e-036
Identities = 95/271 (35%), Positives = 157/271 (57%), Gaps = 15/271 (5%)
Frame = -2
Query: 1357 LLTLDRPKALNAMNLDMDKKYRRYLDEWEVDPKVKCVLVEGSTPRGFSAGGDVKQISTLK 1178
++TL+RPK LNA++L+M ++ L WE DP ++++G+ + F AGGD+K +S K
Sbjct: 47 VITLNRPKFLNALSLNMIRQIYPQLKTWEQDPDTFLIIIKGAGGKAFCAGGDIKALSEAK 106
Query: 1177 QLSEII--EVFTSEYSLICKISEYKKPYISFMDGITMGFGIGLSGHGRYRVITERTVLAM 1004
+ + + ++F EY L I+ +KPY++ +DGITMG G+GLS HG++RV TER++ AM
Sbjct: 107 KARQNLTQDLFREEYILNNAIASCQKPYVALIDGITMGGGVGLSVHGQFRVATERSLFAM 166
Query: 1003 PENAIGLFPDVGFAYIAARSPGGGSVGAYLGMTGNRVSTPADALYVGLGNYFVPSGNLSS 824
PE IGLFPDVG Y R G +G +L +TG R+ D G+ +FV S L
Sbjct: 167 PETGIGLFPDVGGGYFLPRLQ--GKLGYFLALTGYRLK-GRDVHRAGIATHFVDSEKLRV 223
Query: 823 IKDSLLLTTFFEDPHRE-VQATLEKYSSNPESEPRLKLL----LPHIVSTFGSNKSVKEI 659
+++ LL + P E V LE Y + + + ++ + I S F +N +V++I
Sbjct: 224 LEEELLA---LKSPSAEDVAGVLESYHAKSKMDQDKSIIFEEHMDKINSCFSAN-TVEQI 279
Query: 658 MDELEKYQVAEWAKDALSGLKRGAPFSLSLT 566
++ L + + +A + + + + +P SL +T
Sbjct: 280 IENL-RQDGSPFAIEQMKVINKMSPTSLKIT 309
>sp|Q58EB4|HIBCH_DANRE 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Danio
rerio GN=hibch PE=2 SV=1
Length = 382
Score = 149 bits (375), Expect = 7e-035
Identities = 95/269 (35%), Positives = 146/269 (54%), Gaps = 11/269 (4%)
Frame = -2
Query: 1357 LLTLDRPKALNAMNLDMDKKYRRYLDEWEVDPKVKCVLVEGSTPRGFSAGGDVKQISTLK 1178
++TL+RPKALNA+ L+M + L +W+ D + V+++G+ + F AGGD++ I+
Sbjct: 44 VITLNRPKALNALTLNMIRHIYPQLKKWDKDSETDIVIIKGAGEKAFCAGGDIRAIAEAG 103
Query: 1177 QLSEIIE--VFTSEYSLICKISEYKKPYISFMDGITMGFGIGLSGHGRYRVITERTVLAM 1004
+ ++ F EY L I Y+KPY++ ++GITMG G+GLS HG++RV TE+T+ AM
Sbjct: 104 KAGNLLSQVFFREEYILNNTIGTYQKPYVALINGITMGGGVGLSVHGQFRVATEKTLFAM 163
Query: 1003 PENAIGLFPDVGFAYIAARSPGGGSVGAYLGMTGNRVSTPADALYVGLGNYFVPSGNLSS 824
PE IGLFPDVG Y R G +G +L +TG R+ D VG+ +FV S + S
Sbjct: 164 PETGIGLFPDVGGGYFLPRLQ--GKLGLFLALTGFRLK-GRDVQRVGVATHFVQSEKIES 220
Query: 823 IKDSLLLTTFFEDPHREVQATLEKYSSNPESEPRLKLLL---PHIVSTFGSNKSVKEIMD 653
++ L+ +V L+ Y + +L + S SV+EI++
Sbjct: 221 LEKDLV--DLKSPSISDVAQLLDSYQEQSHLDAEKPFVLQEQTEAIDRLFSAGSVEEIVE 278
Query: 652 ELEKYQVAEWAKDALSGLKRGAPFSLSLT 566
L+K A K A L + +P SL LT
Sbjct: 279 NLKKDGSAFALKQA-ETLAKMSPTSLKLT 306
>sp|Q1PEY5|HIBC2_ARATH Probable 3-hydroxyisobutyryl-CoA hydrolase 2
OS=Arabidopsis thaliana GN=At2g30650 PE=2 SV=1
Length = 378
Score = 146 bits (367), Expect = 6e-034
Identities = 93/274 (33%), Positives = 147/274 (53%), Gaps = 12/274 (4%)
Frame = -2
Query: 1369 NGLALLTLDRPKALNAMNLDMDKKYRRYLDEWEVDPKVKCVLVEGSTPRGFSAGGDVKQI 1190
+ + +LT +RPK LNA++ M + + +E DP VK V+++G R FSAGGD+ I
Sbjct: 13 SSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQ-GRAFSAGGDIPPI 71
Query: 1189 STLKQLSEII---EVFTSEYSLICKISEYKKPYISFMDGITMGFGIGLSGHGRYRVITER 1019
++I F Y+L +S Y+KP +S ++GI MG G GLS +GR+R+ TE
Sbjct: 72 VRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATEN 131
Query: 1018 TVLAMPENAIGLFPDVGFAYIAARSPGGGSVGAYLGMTGNRVSTPADALYVGLGNYFVPS 839
TV AMPE A+GLFPDVG +Y +R P G G Y+G+TG R+ A+ L GL +FVPS
Sbjct: 132 TVFAMPETALGLFPDVGASYFLSRLP--GFFGEYVGLTGARLD-GAEMLACGLATHFVPS 188
Query: 838 GNLSSIKDSLLLTTFFEDPHREVQATLEKYSSNPESEPRLKLLLPHIVSTFGSNKSVKEI 659
+L++++ L + L+ Y+ P ++ S ++V+EI
Sbjct: 189 ISLTALEAELYKVG--SSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEI 246
Query: 658 MDELEK---YQVAEWAKDALSGLKRGAPFSLSLT 566
LE+ + +W + L++ +P L ++
Sbjct: 247 FSALEREVTQKPNDWLLATIQALEKASPSCLKIS 280
>sp|P28817|HIBCH_YEAST 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EHD3 PE=1
SV=2
Length = 500
Score = 137 bits (344), Expect = 3e-031
Identities = 82/202 (40%), Positives = 119/202 (58%), Gaps = 11/202 (5%)
Frame = -2
Query: 1357 LLTLDRPKALNAMNLDMDKKYRRYLDEWEVDPKVKCVLVEGST-PRGFSAGGDVKQISTL 1181
++TL+RPK LNA+N +M + + L+E+ V+++ S PR F AGGDV ++
Sbjct: 49 VITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFCAGGDVATVAIF 108
Query: 1180 ---KQLSEIIEVFTSEYSLICKISEYKKPYISFMDGITMGFGIGLSGHGRYRVITERTVL 1010
K+ ++ I+ FT EYSL +I+ Y KP ++FMDGITMG G+GLS H +R+ TE T
Sbjct: 109 NFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSIHTPFRIATENTKW 168
Query: 1009 AMPENAIGLFPDVGFAY----IAARSPGGGSVGAYLGMTGNRVSTPADALYVGLGNYFVP 842
AMPE IG FPDVG + I + + YL +TG V T ADA +GL +++V
Sbjct: 169 AMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTG-EVVTGADAYMLGLASHYVS 227
Query: 841 SGNLSSIKDSL--LLTTFFEDP 782
S NL +++ L + F DP
Sbjct: 228 SENLDALQKRLGEISPPFNNDP 249
>sp|O74802|HIBCH_SCHPO 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ehd3 PE=2
SV=1
Length = 429
Score = 128 bits (321), Expect = 1e-028
Identities = 91/286 (31%), Positives = 144/286 (50%), Gaps = 17/286 (5%)
Frame = -2
Query: 1369 NGLALLTLDRPKALNAMNLDMDKKYRRYLDEWEVDPKVKCVLVEGSTPRGFSAGGDVKQI 1190
NG + TL+RPK LNA+N+DM L E K ++++G+ R FS+GGD+K
Sbjct: 64 NGARIFTLNRPKVLNAINVDMIDSILPKLVSLEESNLAKVIILKGN-GRSFSSGGDIKAA 122
Query: 1189 STLKQ---LSEIIEVFTSEYSLICKISEYKKPYISFMDGITMGFGIGLSGHGRYRVITER 1019
+ Q L E+ F EY L ++ Y+KP ++ M+GITMG G GL+ H +R+ E
Sbjct: 123 ALSIQDGKLPEVRHAFAQEYRLSHTLATYQKPVVALMNGITMGGGSGLAMHVPFRIACED 182
Query: 1018 TVLAMPENAIGLFPDVGFAYIAARSPGGGSVGAYLGMTGNRVSTPADALYVGLGNYFVPS 839
T+ AMPE IG F DV ++ +R P G G YLG+T +++ D L G+ +FVP
Sbjct: 183 TMFAMPETGIGYFTDVAASFFFSRLP--GYFGTYLGLT-SQIVKGYDCLRTGIATHFVPK 239
Query: 838 GNLSSIKDSL--LLTTFFEDPHREVQATLEKYSSNPESEPRLKLLLPHIVSTFGSNKSVK 665
++D L L T+ + + E SS+P P + +++
Sbjct: 240 HMFPHLEDRLAELNTSDISKINNTILEFAEFASSSP---PTFTPDVMDVINKCFCKNDTV 296
Query: 664 EIMDELEKY-----QVAEWAKDALSGLKRGAPFSLSLTQHYFSRVA 542
+I+ L++Y +AE+AK + L +P S+++T A
Sbjct: 297 DIIRALKEYASNTSALAEFAKSTVKTLYSKSPTSIAVTNRLIKSAA 342
>sp|Q8RXN4|HIBC5_ARATH 3-hydroxyisobutyryl-CoA hydrolase-like protein 2,
mitochondrial OS=Arabidopsis thaliana GN=At4g31810 PE=2 SV=1
Length = 409
Score = 118 bits (294), Expect = 2e-025
Identities = 92/308 (29%), Positives = 153/308 (49%), Gaps = 19/308 (6%)
Frame = -2
Query: 1456 IRSKQFNSIFCRKLSVMASGEFVKGNVYPNGLA---LLTLDRPKALNAMNLDMDKKYRRY 1286
+RS + F + AS + V G A L+ P +LNA++ M + +R
Sbjct: 17 VRSVSYGRRFSALPNYSASDADFEDQVLVEGKAKSRAAILNNPSSLNALSAPMVGRLKRL 76
Query: 1285 LDEWEVDPKVKCVLVEGSTPRGFSAGGDVKQI--STLKQLSEIIEVFTSE-YSLICKISE 1115
+ WE +P + VL++GS + F +G DV + S + +E ++F Y +
Sbjct: 77 YESWEENPAISFVLMKGS-GKTFCSGADVLSLYHSINEGNTEESKLFFENLYKFVYLQGT 135
Query: 1114 YKKPYISFMDGITMGFGIGLSGHGRYRVITERTVLAMPENAIGLFPDVGFAYIAARSPGG 935
Y KP I+ MDG+TMG G G+S G +RV T++TVLA PE IG PD G +Y +R P
Sbjct: 136 YLKPNIAIMDGVTMGCGGGISLPGMFRVATDKTVLAHPEVQIGFHPDAGASYYLSRLP-- 193
Query: 934 GSVGAYLGMTGNRVSTPADALYVGLGNYFVPSGNLSSIKDSL--LLTTFFEDPHREVQAT 761
G +G YL +TG +++ + + GL ++ + L I++ + LLT +DP ++ +
Sbjct: 194 GYLGEYLALTGQKLN-GVEMIACGLATHYCLNARLPLIEERIGKLLT---DDP-AVIEDS 248
Query: 760 LEKYSSNPESEPRLKLLLPHIVSTFGSNKSVKEIMDELEK---YQVAEWAKDALSGLKRG 590
L +Y + L ++ + +V+EI++ +E EW K L +K
Sbjct: 249 LAQYGDLVYPDSSSVLHKIELIDKYFGLDTVEEIIEAMENEAANSCNEWCKKTLKQIKEA 308
Query: 589 APFSLSLT 566
+P SL +T
Sbjct: 309 SPLSLKIT 316
Database: Uniprot/SwissProt
Posted date: Thu Sep 27 17:53:50 2012
Number of letters in database: 190,795,139
Number of sequences in database: 537,505
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 132,281,544,548
Number of Sequences: 537505
Number of Extensions: 132281544548
Number of Successful Extensions: 794851505
Number of sequences better than 0.0: 0
|