SwissProt blast output of UN61069
BLASTX 7.6.2
Query= UN61069 /QuerySize=2475
(2474 letters)
Database: Uniprot/SwissProt;
537,505 sequences; 190,795,139 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5ZIW5|VAC14_CHICK Protein VAC14 homolog OS=Gallus gallus GN=... 280 6e-074
sp|Q68F38|VAC14_XENLA Protein VAC14 homolog OS=Xenopus laevis GN... 280 6e-074
sp|Q08AM6|VAC14_HUMAN Protein VAC14 homolog OS=Homo sapiens GN=V... 276 8e-073
sp|A2VE70|VAC14_BOVIN Protein VAC14 homolog OS=Bos taurus GN=VAC... 275 1e-072
sp|Q80WQ2|VAC14_MOUSE Protein VAC14 homolog OS=Mus musculus GN=V... 273 7e-072
sp|Q80W92|VAC14_RAT Protein VAC14 homolog OS=Rattus norvegicus G... 272 1e-071
sp|Q66L58|VAC14_DANRE Protein VAC14 homolog OS=Danio rerio GN=va... 269 8e-071
sp|P87145|VAC14_SCHPO Protein VAC14 homolog OS=Schizosaccharomyc... 217 3e-055
sp|Q06708|VAC14_YEAST Vacuole morphology and inheritance protein... 153 8e-036
>sp|Q5ZIW5|VAC14_CHICK Protein VAC14 homolog OS=Gallus gallus GN=VAC14 PE=2
SV=1
Length = 780
Score = 280 bits (714), Expect = 6e-074
Identities = 143/307 (46%), Positives = 208/307 (67%), Gaps = 3/307 (0%)
Frame = -2
Query: 2473 KRKNAAIEVEGIVKQLTAAGDHDKITSVINLLTHDFTYSPQINYRKGGLIGLAAATVGLS 2294
KRK AA+E+E +V++ A + ++ VI +L+ +F S + RKGGLIGLAA ++ L
Sbjct: 25 KRKVAALEIEKLVREFVAQNNTSQVKHVILILSQEFALSQHPHSRKGGLIGLAACSIALG 84
Query: 2293 AEAAQHLEQILPPVINSFSDQDSRVRYYACEALYNIAKVVRGEFIFHFNKIFDALCKLSA 2114
++ +L++++ PV+ F+D DSR+RYYACEALYNI KV RG + HFN +FD L KL+A
Sbjct: 85 KDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGSVLPHFNVLFDGLSKLAA 144
Query: 2113 DSDPNVQSAAHLLDRLVKDIVTESDQFSIEEFIPLLRERMNVLNPYVRQFLVGWITVLDS 1934
D DPNV+S + LLDRL+KDIVTES+QF + FIPLLRER+ N Y RQF++ WI VL+S
Sbjct: 145 DPDPNVKSGSELLDRLLKDIVTESNQFDLVGFIPLLRERIYSNNQYARQFIISWILVLES 204
Query: 1933 VPDIDMXXXXXXXXXXXXNMLSDSSHEIRQQADSALSEFLQEIKNSP-SVDYGRMAEILV 1757
VPDI++ +L D+S EIR+ + AL EFL+EIK +P SV + MA ILV
Sbjct: 205 VPDINLLDYLPEILDGLFQILGDNSKEIRKMCEVALGEFLKEIKKNPSSVKFAEMANILV 264
Query: 1756 QRAASPDEFTRWTAITWIYEFVKLGGDQLVPYYADILGAILPCIA--DKEEKIRVVACET 1583
+ D+ + TA+ W+ EF++L G ++PY + IL A+LPC++ D+++ I+ VA
Sbjct: 265 IHCQAADDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLSYDDRKKNIKEVANVC 324
Query: 1582 NEELLAI 1562
N+ L+ +
Sbjct: 325 NQSLMKL 331
Score = 160 bits (403), Expect = 7e-038
Identities = 100/237 (42%), Positives = 138/237 (58%), Gaps = 14/237 (5%)
Frame = -2
Query: 1303 FRQLVIFLVHKFRTDDVLLEKRGPLIIRRLCVLIDAERVYRELSTILEGEADLGFASTMV 1124
F + +I L+ +F ++ LLE RG IIR+LC+L++ E ++ ++ IL E DL FASTMV
Sbjct: 525 FYKFMINLLKRFSSERKLLETRGAFIIRQLCLLLNTENIFHSMADILLREEDLKFASTMV 584
Query: 1123 QALNLILLTSSELSDIRNLLKLSLVNAAGKDFFLXXXXXXXXXXXXXXXLCLLAQAYQHA 944
LN ILLTSSEL +RN LK L ++ F LC L Q Y+HA
Sbjct: 585 HTLNTILLTSSELFQLRNQLK-DLRTPESRNLFCCLYRSWCHNPVTTVSLCFLTQNYKHA 643
Query: 943 SSVIQSLTEEDINVIFLVQLDKFIHLLETPIFAYLRLQLLEPGRYTWLLKALYGLIMLLP 764
+IQ + ++ V FL ++DK + L+E PIF YLRLQLL+ +L+KALYGL+MLLP
Sbjct: 644 YDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLP 703
Query: 763 QQSTAFKILRTRLKTVPSYSFNKEQIQ-------RTSSGNPSTET-DYMSSGLHFSE 617
QS+AF++L RL+ VP N E +Q SS P++ T DY HF +
Sbjct: 704 -QSSAFQLLSHRLQCVP----NPELMQSADGSRASASSRRPASSTIDYTELLQHFDK 755
>sp|Q68F38|VAC14_XENLA Protein VAC14 homolog OS=Xenopus laevis GN=vac14 PE=2
SV=1
Length = 782
Score = 280 bits (714), Expect = 6e-074
Identities = 143/307 (46%), Positives = 207/307 (67%), Gaps = 3/307 (0%)
Frame = -2
Query: 2473 KRKNAAIEVEGIVKQLTAAGDHDKITSVINLLTHDFTYSPQINYRKGGLIGLAAATVGLS 2294
KRK AA+E+E +V++ + + +I VI +L+ +F S + RKGGLIGLAA ++ L
Sbjct: 25 KRKVAALEIEKLVREFVSQNNTAQIKHVIQILSQEFALSQHPHSRKGGLIGLAACSIALG 84
Query: 2293 AEAAQHLEQILPPVINSFSDQDSRVRYYACEALYNIAKVVRGEFIFHFNKIFDALCKLSA 2114
++ Q+L +++ PV+ F+D DSR+RYYACEALYNI KV RG + HFN +FD L KL+A
Sbjct: 85 KDSGQYLRELIEPVLTCFNDADSRLRYYACEALYNIVKVARGSVLPHFNVLFDGLSKLAA 144
Query: 2113 DSDPNVQSAAHLLDRLVKDIVTESDQFSIEEFIPLLRERMNVLNPYVRQFLVGWITVLDS 1934
D DPNV+S + LLDRL+KDIVTES +F + F+PLLRER+ N Y RQF++ WI VL+S
Sbjct: 145 DPDPNVKSGSELLDRLLKDIVTESSKFDLVGFVPLLRERIYSNNQYARQFIISWILVLES 204
Query: 1933 VPDIDMXXXXXXXXXXXXNMLSDSSHEIRQQADSALSEFLQEIKNSP-SVDYGRMAEILV 1757
VPDI++ +L D+S EIR+ + +L EFL+EIK P SV + MA ILV
Sbjct: 205 VPDINLLDYLPEILDGLFQILGDNSKEIRKMCEVSLGEFLKEIKKLPDSVKFAEMANILV 264
Query: 1756 QRAASPDEFTRWTAITWIYEFVKLGGDQLVPYYADILGAILPCIA--DKEEKIRVVACET 1583
S D+ + TA+TW+ EF++L G ++PY + IL A+LPC++ D+++ I+ VA
Sbjct: 265 IHCQSTDDLIQLTAMTWMREFLQLAGRVMLPYSSGILTAVLPCLSYDDRKKNIKEVANVC 324
Query: 1582 NEELLAI 1562
N+ L+ +
Sbjct: 325 NQSLMKL 331
Score = 159 bits (400), Expect = 1e-037
Identities = 96/234 (41%), Positives = 138/234 (58%), Gaps = 8/234 (3%)
Frame = -2
Query: 1303 FRQLVIFLVHKFRTDDVLLEKRGPLIIRRLCVLIDAERVYRELSTILEGEADLGFASTMV 1124
F + ++ L+ +F + LLE RG IIR+LC+L++AE ++ ++ IL E DL FASTMV
Sbjct: 527 FHRFMVNLLKRFSNERKLLEIRGAFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMV 586
Query: 1123 QALNLILLTSSELSDIRNLLKLSLVNAAGKDFFLXXXXXXXXXXXXXXXLCLLAQAYQHA 944
Q LN ILLTSSEL +R+ LK L + F LC L Q YQHA
Sbjct: 587 QNLNSILLTSSELFQLRSQLK-DLQTPESCNLFCCLYRSWCHNPVATVSLCFLTQNYQHA 645
Query: 943 SSVIQSLTEEDINVIFLVQLDKFIHLLETPIFAYLRLQLLEPGRYTWLLKALYGLIMLLP 764
++IQ + ++ V FL ++DK + L+E PIF YLRLQLL+ +L++ALYGL+MLLP
Sbjct: 646 YNLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVENNPYLIRALYGLLMLLP 705
Query: 763 QQSTAFKILRTRLKTVPSYSF-----NKEQIQRTSSGNPSTETDYMSSGLHFSE 617
QS+AF++L RL+ VP+ +E+ R +P+ DY+ HF +
Sbjct: 706 -QSSAFQLLSHRLQCVPNPQLMRPGHKQEESSRAPKEDPA-RIDYVELLQHFEK 757
>sp|Q08AM6|VAC14_HUMAN Protein VAC14 homolog OS=Homo sapiens GN=VAC14 PE=1 SV=1
Length = 782
Score = 276 bits (704), Expect = 8e-073
Identities = 142/307 (46%), Positives = 205/307 (66%), Gaps = 3/307 (0%)
Frame = -2
Query: 2473 KRKNAAIEVEGIVKQLTAAGDHDKITSVINLLTHDFTYSPQINYRKGGLIGLAAATVGLS 2294
KRK AA+E+E +V++ A + +I VI L+ +F S + RKGGLIGLAA ++ L
Sbjct: 25 KRKVAALEIEKLVREFVAQNNTVQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALG 84
Query: 2293 AEAAQHLEQILPPVINSFSDQDSRVRYYACEALYNIAKVVRGEFIFHFNKIFDALCKLSA 2114
++ +L++++ PV+ F+D DSR+RYYACEALYNI KV RG + HFN +FD L KL+A
Sbjct: 85 KDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAA 144
Query: 2113 DSDPNVQSAAHLLDRLVKDIVTESDQFSIEEFIPLLRERMNVLNPYVRQFLVGWITVLDS 1934
D DPNV+S + LLDRL+KDIVTES++F + FIPLLRER+ N Y RQF++ WI VL+S
Sbjct: 145 DPDPNVKSGSELLDRLLKDIVTESNKFDLVSFIPLLRERIYSNNQYARQFIISWILVLES 204
Query: 1933 VPDIDMXXXXXXXXXXXXNMLSDSSHEIRQQADSALSEFLQEIKNSP-SVDYGRMAEILV 1757
VPDI++ +L D+ EIR+ + L EFL+EIK +P SV + MA ILV
Sbjct: 205 VPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILV 264
Query: 1756 QRAASPDEFTRWTAITWIYEFVKLGGDQLVPYYADILGAILPCIA--DKEEKIRVVACET 1583
+ D+ + TA+ W+ EF++L G ++PY + IL A+LPC+A D+++ I+ VA
Sbjct: 265 IHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKKSIKEVANVC 324
Query: 1582 NEELLAI 1562
N+ L+ +
Sbjct: 325 NQSLMKL 331
Score = 163 bits (410), Expect = 1e-038
Identities = 95/211 (45%), Positives = 131/211 (62%), Gaps = 6/211 (2%)
Frame = -2
Query: 1303 FRQLVIFLVHKFRTDDVLLEKRGPLIIRRLCVLIDAERVYRELSTILEGEADLGFASTMV 1124
F + +I L+ +F ++ LLE RGP IIR+LC+L++AE ++ ++ IL E DL FASTMV
Sbjct: 527 FYKFMINLLKRFSSERKLLEVRGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMV 586
Query: 1123 QALNLILLTSSELSDIRNLLKLSLVNAAGKDFFLXXXXXXXXXXXXXXXLCLLAQAYQHA 944
ALN ILLTS+EL +RN LK L ++ F LC L Q Y+HA
Sbjct: 587 HALNTILLTSTELFQLRNQLK-DLKTLESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHA 645
Query: 943 SSVIQSLTEEDINVIFLVQLDKFIHLLETPIFAYLRLQLLEPGRYTWLLKALYGLIMLLP 764
+IQ + ++ V FL ++DK + L+E PIF YLRLQLL+ +L+KALYGL+MLLP
Sbjct: 646 YDLIQKFGDLEVTVDFLAEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLP 705
Query: 763 QQSTAFKILRTRLKTVPSYSFNKEQIQRTSS 671
QS+AF++L RL+ VP N E +Q S
Sbjct: 706 -QSSAFQLLSHRLQCVP----NPELLQTEDS 731
>sp|A2VE70|VAC14_BOVIN Protein VAC14 homolog OS=Bos taurus GN=VAC14 PE=2 SV=1
Length = 783
Score = 275 bits (702), Expect = 1e-072
Identities = 142/307 (46%), Positives = 203/307 (66%), Gaps = 3/307 (0%)
Frame = -2
Query: 2473 KRKNAAIEVEGIVKQLTAAGDHDKITSVINLLTHDFTYSPQINYRKGGLIGLAAATVGLS 2294
KRK AA+E+E +V++ A + +I VI L+ +F S + RKGGLIGLAA ++ L
Sbjct: 25 KRKVAALEIEKLVREFVAQNNTVQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALG 84
Query: 2293 AEAAQHLEQILPPVINSFSDQDSRVRYYACEALYNIAKVVRGEFIFHFNKIFDALCKLSA 2114
++ +L++++ PV+ F+D DSR+RYYACEALYNI KV RG + HFN +FD L KL+A
Sbjct: 85 KDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAA 144
Query: 2113 DSDPNVQSAAHLLDRLVKDIVTESDQFSIEEFIPLLRERMNVLNPYVRQFLVGWITVLDS 1934
D DPNV+S + LLDRL+KDIVTES++F + FIPLLRER+ N Y RQF++ WI VL+S
Sbjct: 145 DPDPNVKSGSELLDRLLKDIVTESNKFDLVGFIPLLRERIYSNNQYARQFIISWILVLES 204
Query: 1933 VPDIDMXXXXXXXXXXXXNMLSDSSHEIRQQADSALSEFLQEIKNSP-SVDYGRMAEILV 1757
VPDI++ +L D+ EIR+ + L EFL+E K SP SV + MA ILV
Sbjct: 205 VPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKETKKSPSSVKFAEMANILV 264
Query: 1756 QRAASPDEFTRWTAITWIYEFVKLGGDQLVPYYADILGAILPCIA--DKEEKIRVVACET 1583
+ D+ + TA+ W+ EF++L G ++PY + IL A+LPC+A D++ I+ VA
Sbjct: 265 IHCQTTDDLIQLTAMCWLREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKRNIKEVASVC 324
Query: 1582 NEELLAI 1562
N+ L+ +
Sbjct: 325 NQSLMKL 331
Score = 156 bits (394), Expect = 7e-037
Identities = 89/198 (44%), Positives = 124/198 (62%), Gaps = 2/198 (1%)
Frame = -2
Query: 1303 FRQLVIFLVHKFRTDDVLLEKRGPLIIRRLCVLIDAERVYRELSTILEGEADLGFASTMV 1124
F + +I L+ +F ++ LLE RG IIR+LC+L+ AE ++ ++ IL E DL FASTMV
Sbjct: 528 FYKFMINLLKRFSSERKLLEVRGAFIIRQLCLLLHAESIFHSMADILLREEDLTFASTMV 587
Query: 1123 QALNLILLTSSELSDIRNLLKLSLVNAAGKDFFLXXXXXXXXXXXXXXXLCLLAQAYQHA 944
LN ILLTS+EL +RN LK L ++ F LC L Q Y+HA
Sbjct: 588 HTLNTILLTSTELFQLRNQLK-DLKTPESRNLFCCLYRSWCHKPVTTVSLCFLTQNYRHA 646
Query: 943 SSVIQSLTEEDINVIFLVQLDKFIHLLETPIFAYLRLQLLEPGRYTWLLKALYGLIMLLP 764
+IQ + ++ V FL ++DK + L+E PIF YLRLQLL+ +L+KALYGL+MLLP
Sbjct: 647 YDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKSNPYLIKALYGLLMLLP 706
Query: 763 QQSTAFKILRTRLKTVPS 710
QS+AF++L RL+ VP+
Sbjct: 707 -QSSAFQLLSHRLQCVPN 723
>sp|Q80WQ2|VAC14_MOUSE Protein VAC14 homolog OS=Mus musculus GN=Vac14 PE=1 SV=1
Length = 782
Score = 273 bits (696), Expect = 7e-072
Identities = 142/307 (46%), Positives = 202/307 (65%), Gaps = 3/307 (0%)
Frame = -2
Query: 2473 KRKNAAIEVEGIVKQLTAAGDHDKITSVINLLTHDFTYSPQINYRKGGLIGLAAATVGLS 2294
KRK AA+E+E +V+ A + +I VI L+ +F S + RKGGLIGLAA ++ L
Sbjct: 25 KRKVAALEIEKLVRDFVAQNNTMQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALG 84
Query: 2293 AEAAQHLEQILPPVINSFSDQDSRVRYYACEALYNIAKVVRGEFIFHFNKIFDALCKLSA 2114
++ +L++++ PV+ F+D DSR+RYYACEALYNI KV RG + HFN +FD L KL+A
Sbjct: 85 KDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAA 144
Query: 2113 DSDPNVQSAAHLLDRLVKDIVTESDQFSIEEFIPLLRERMNVLNPYVRQFLVGWITVLDS 1934
D DPNV+S + LLDRL+KDIVTES +F + FIPLLRER+ N Y RQF++ WI VL S
Sbjct: 145 DPDPNVKSGSELLDRLLKDIVTESSKFDLVSFIPLLRERIYSNNQYARQFIISWILVLVS 204
Query: 1933 VPDIDMXXXXXXXXXXXXNMLSDSSHEIRQQADSALSEFLQEIKNSP-SVDYGRMAEILV 1757
VPDI++ +L D+ EIR+ + L EFL+EIK +P SV + MA ILV
Sbjct: 205 VPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILV 264
Query: 1756 QRAASPDEFTRWTAITWIYEFVKLGGDQLVPYYADILGAILPCIA--DKEEKIRVVACET 1583
+ D+ + TA+ W+ EF++L G ++PY + IL A+LPC+A D+++ I+ VA
Sbjct: 265 IHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKKSIKEVANVC 324
Query: 1582 NEELLAI 1562
N+ L+ +
Sbjct: 325 NQSLMKL 331
Score = 160 bits (404), Expect = 5e-038
Identities = 90/198 (45%), Positives = 125/198 (63%), Gaps = 2/198 (1%)
Frame = -2
Query: 1303 FRQLVIFLVHKFRTDDVLLEKRGPLIIRRLCVLIDAERVYRELSTILEGEADLGFASTMV 1124
F + +I L+ F ++ LLE RGP IIR+LC+L++AE ++ ++ IL E DL FASTMV
Sbjct: 527 FYKFMINLLQTFSSERKLLEARGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMV 586
Query: 1123 QALNLILLTSSELSDIRNLLKLSLVNAAGKDFFLXXXXXXXXXXXXXXXLCLLAQAYQHA 944
LN ILLTS+EL +RN LK L ++ F LC L Q Y+HA
Sbjct: 587 HTLNTILLTSTELFQLRNQLK-DLQTPESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHA 645
Query: 943 SSVIQSLTEEDINVIFLVQLDKFIHLLETPIFAYLRLQLLEPGRYTWLLKALYGLIMLLP 764
+IQ + ++ V FL ++DK + L+E PIF YLRLQLL+ +L+KALYGL+MLLP
Sbjct: 646 YDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLP 705
Query: 763 QQSTAFKILRTRLKTVPS 710
QS+AF++L RL+ VP+
Sbjct: 706 -QSSAFQLLSHRLQCVPN 722
>sp|Q80W92|VAC14_RAT Protein VAC14 homolog OS=Rattus norvegicus GN=Vac14 PE=1
SV=1
Length = 783
Score = 272 bits (694), Expect = 1e-071
Identities = 142/307 (46%), Positives = 202/307 (65%), Gaps = 3/307 (0%)
Frame = -2
Query: 2473 KRKNAAIEVEGIVKQLTAAGDHDKITSVINLLTHDFTYSPQINYRKGGLIGLAAATVGLS 2294
KRK AA+E+E +V+ A + +I VI L+ +F S + RKGGLIGLAA ++ L
Sbjct: 25 KRKVAALEIEKLVRDFVAQNNTVQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALG 84
Query: 2293 AEAAQHLEQILPPVINSFSDQDSRVRYYACEALYNIAKVVRGEFIFHFNKIFDALCKLSA 2114
++ +L++++ PV+ F+D DSR+RYYACEALYNI KV RG + HFN +FD L KL+A
Sbjct: 85 KDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAA 144
Query: 2113 DSDPNVQSAAHLLDRLVKDIVTESDQFSIEEFIPLLRERMNVLNPYVRQFLVGWITVLDS 1934
D DPNV+S + LLDRL+KDIVTES +F + FIPLLRER+ N Y RQF++ WI VL S
Sbjct: 145 DPDPNVKSGSELLDRLLKDIVTESSKFDLVGFIPLLRERIYSNNQYARQFIISWILVLVS 204
Query: 1933 VPDIDMXXXXXXXXXXXXNMLSDSSHEIRQQADSALSEFLQEIKNSP-SVDYGRMAEILV 1757
VPDI++ +L D+ EIR+ + L EFL+EIK +P SV + MA ILV
Sbjct: 205 VPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILV 264
Query: 1756 QRAASPDEFTRWTAITWIYEFVKLGGDQLVPYYADILGAILPCIA--DKEEKIRVVACET 1583
+ D+ + TA+ W+ EF++L G ++PY + IL A+LPC+A D+++ I+ VA
Sbjct: 265 IHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKKSIKEVANVC 324
Query: 1582 NEELLAI 1562
N+ L+ +
Sbjct: 325 NQSLMKL 331
Score = 160 bits (404), Expect = 5e-038
Identities = 90/198 (45%), Positives = 125/198 (63%), Gaps = 2/198 (1%)
Frame = -2
Query: 1303 FRQLVIFLVHKFRTDDVLLEKRGPLIIRRLCVLIDAERVYRELSTILEGEADLGFASTMV 1124
F + +I L+ F ++ LLE RGP IIR+LC+L++AE ++ ++ IL E DL FASTMV
Sbjct: 528 FYKFMINLLQTFSSERKLLEARGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMV 587
Query: 1123 QALNLILLTSSELSDIRNLLKLSLVNAAGKDFFLXXXXXXXXXXXXXXXLCLLAQAYQHA 944
LN ILLTS+EL +RN LK L ++ F LC L Q Y+HA
Sbjct: 588 HTLNTILLTSTELFQLRNQLK-DLKTLESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHA 646
Query: 943 SSVIQSLTEEDINVIFLVQLDKFIHLLETPIFAYLRLQLLEPGRYTWLLKALYGLIMLLP 764
+IQ + ++ V FL ++DK + L+E PIF YLRLQLL+ +L+KALYGL+MLLP
Sbjct: 647 YDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLMKALYGLLMLLP 706
Query: 763 QQSTAFKILRTRLKTVPS 710
QS+AF++L RL+ VP+
Sbjct: 707 -QSSAFQLLSHRLQCVPN 723
>sp|Q66L58|VAC14_DANRE Protein VAC14 homolog OS=Danio rerio GN=vac14 PE=2 SV=1
Length = 771
Score = 269 bits (687), Expect = 8e-071
Identities = 140/313 (44%), Positives = 205/313 (65%), Gaps = 9/313 (2%)
Frame = -2
Query: 2473 KRKNAAIEVEGIVKQLTAAGDHDKITSVINLLTHDFTYSPQINYRKGGLIGLAAATVGLS 2294
KRK AA+E+E +V++ A + +I VI +L +F S + RKGGLIGLAA ++ L
Sbjct: 25 KRKVAALEIEKLVREFVAQNNSAQIRHVIQILATEFALSQHPHSRKGGLIGLAACSIALG 84
Query: 2293 AEAAQHLEQILPPVINSFSDQDSRVRYYACEALYNIAKVVRGEFIFHFNKIFDALCKLSA 2114
++ +L++++ PV+ F+D DSR+RYYACEALYNI KV RG + HFN +FD L KL+A
Sbjct: 85 KDSGLYLKELIDPVLTCFNDSDSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAA 144
Query: 2113 DSDPNVQSAAHLLDRLVKDIVTESDQFSIEEFIPLLRERMNVLNPYVRQFLVGWITVLDS 1934
D DPNV+S + LLDRL+KDIVTES++F + F+PLLRER+ N Y RQF++ WI VL+S
Sbjct: 145 DPDPNVKSGSELLDRLLKDIVTESNKFDLVAFVPLLRERIYSNNQYARQFIISWIHVLES 204
Query: 1933 VPDIDMXXXXXXXXXXXXNMLSDSSHEIRQQADSALSEFLQEIKNSP-SVDYGRMAEILV 1757
VPDI++ +L DSS EIR+ + L EFL+EIK +P SV + MA ILV
Sbjct: 205 VPDINLLDYLPEILDGLFQILGDSSKEIRRMCELVLGEFLKEIKKNPSSVKFAEMANILV 264
Query: 1756 ------QRAASPDEFTRWTAITWIYEFVKLGGDQLVPYYADILGAILPCIA--DKEEKIR 1601
+ S ++ + T++TW+ EF++L G ++PY + IL A+LPC++ D+++ +
Sbjct: 265 IHCQVSDESKSTNDLIQLTSMTWMREFIQLAGRVVLPYSSGILTAVLPCLSYDDRKKSTK 324
Query: 1600 VVACETNEELLAI 1562
A N L+ +
Sbjct: 325 EAASACNHSLMKL 337
Score = 155 bits (391), Expect = 2e-036
Identities = 90/198 (45%), Positives = 122/198 (61%), Gaps = 2/198 (1%)
Frame = -2
Query: 1303 FRQLVIFLVHKFRTDDVLLEKRGPLIIRRLCVLIDAERVYRELSTILEGEADLGFASTMV 1124
F + +I L+ +F + LLE RG IIR+LC+L+ AE ++ ++ IL E DL FASTMV
Sbjct: 517 FYKFMINLLKRFSLERKLLEMRGAFIIRQLCLLLHAENIFHSMADILLKEEDLKFASTMV 576
Query: 1123 QALNLILLTSSELSDIRNLLKLSLVNAAGKDFFLXXXXXXXXXXXXXXXLCLLAQAYQHA 944
Q LN ILLTS+EL +RN LK L F LC L Q Y+HA
Sbjct: 577 QTLNTILLTSAELFQLRNQLK-DLRTQESCALFCCLYRSWCHNPVATVSLCFLTQNYRHA 635
Query: 943 SSVIQSLTEEDINVIFLVQLDKFIHLLETPIFAYLRLQLLEPGRYTWLLKALYGLIMLLP 764
+IQ + ++ V FL+++DK + L+E+PIF YLRLQLL+ +L+KALYGL+MLLP
Sbjct: 636 YDLIQKFGDLEVTVDFLMEVDKLVQLIESPIFTYLRLQLLDVEHNPYLIKALYGLLMLLP 695
Query: 763 QQSTAFKILRTRLKTVPS 710
QS AF++L RL VP+
Sbjct: 696 -QSQAFQLLSHRLSCVPN 712
>sp|P87145|VAC14_SCHPO Protein VAC14 homolog OS=Schizosaccharomyces pombe
(strain 972 / ATCC 24843) GN=SPBC25H2.03 PE=2 SV=1
Length = 811
Score = 217 bits (552), Expect = 3e-055
Identities = 136/403 (33%), Positives = 217/403 (53%), Gaps = 21/403 (5%)
Frame = -2
Query: 1879 NMLSDSSHEIRQQADSALSEFLQEIKNSPSVDYGRMAEILVQRAASPDEFTRWTAITWIY 1700
NM EI +S+L + ++ +DY R+ EI++ S + A+ W++
Sbjct: 305 NMSDAELKEISDYVESSLRDGSFILEAHIQIDYKRILEIIIDHLGSSVPLIQEKALKWLF 364
Query: 1699 EFVKLGGDQLVPYYADILGAILPCIADKEEKIRVVACETNEELLAI-------------- 1562
EF+ + ++ +L +LP +++ +E +R A + ++ L+ +
Sbjct: 365 EFIYIAPKDVLLQIPKVLENLLPLMSN-DENMRQSAKDLSQNLVILVSKIMDIEFSGSET 423
Query: 1561 -KADPAEGFDVGAILSIVKRQLSSEYEATRIESLHWISTLLNRHRTEVLSFLNDIFDTLL 1385
D + D +++ ++++ LS++ E TR+ +L W+ L R ++++ + IF TLL
Sbjct: 424 NNKDNSLSVDFRSLIEVLQKLLSNDNEETRLCALEWVLLLQRRTGGKLINMHDPIFQTLL 483
Query: 1384 KALSDPSDQVVLLVLEV--HACIAEDQYNFRQLVIFLVHKFRTDDVLLEKRGPLIIRRLC 1211
LSDPSD VV LE+ H I+ N + L+ F D L RG LIIR+LC
Sbjct: 484 LQLSDPSDLVVSRTLELLAHIAISHKSVNLVPFLKSLLQMFAEDRKFLNSRGNLIIRQLC 543
Query: 1210 VLIDAERVYRELSTILEGEADLGFASTMVQALNLILLTSSELSDIRNLLKLSLVNAAGKD 1031
I+ ERVY + ILE E +L AS MV+ LN L T+ EL D+R LK S ++
Sbjct: 544 NYIEGERVYTSFAGILETEENLELASIMVEVLNNNLFTAPELYDLRKKLKQSAPKL--QN 601
Query: 1030 FFLXXXXXXXXXXXXXXXLCLLAQAYQHASSVIQSLTEEDINVIFLVQLDKFIHLLETPI 851
F LCLL+Q Y+HA++++ E + N+ L+QLDK + L+E+P+
Sbjct: 602 IFTTLYTAWCHNSIAVFSLCLLSQNYEHAANLLSVFAEIEFNIDMLIQLDKLVQLIESPV 661
Query: 850 FAYLRLQLLEPGRYTWLLKALYGLIMLLPQQSTAFKILRTRLK 722
F Y+RLQLLEP +Y +L KALYG++MLLP QS+AF+ LR RL+
Sbjct: 662 FTYMRLQLLEPEKYPYLHKALYGILMLLP-QSSAFRTLRDRLQ 703
Score = 135 bits (338), Expect = 2e-030
Identities = 70/143 (48%), Positives = 95/143 (66%), Gaps = 2/143 (1%)
Frame = -2
Query: 2467 KNAAIEVEGIVKQLTAAGDHDKITSVINLLTHDFTYSPQ--INYRKGGLIGLAAATVGLS 2294
K A E+E +VK + +KI +VI+ L +DF YSP N GGLIGLAA + L
Sbjct: 18 KATAYELERVVKGYLENDETEKIRAVISQLANDFVYSPARGPNATFGGLIGLAAVAIALG 77
Query: 2293 AEAAQHLEQILPPVINSFSDQDSRVRYYACEALYNIAKVVRGEFIFHFNKIFDALCKLSA 2114
+ ++E IL PV+ F+D DS++RYYACE++YNI KV +GE +FN IFD LCKL A
Sbjct: 78 PKIDSYMESILLPVLYCFNDSDSKIRYYACESMYNIGKVAKGEVFRYFNLIFDVLCKLFA 137
Query: 2113 DSDPNVQSAAHLLDRLVKDIVTE 2045
D++ V++ A LLDRL+KDIV +
Sbjct: 138 DTEITVKNGAELLDRLIKDIVMQ 160
>sp|Q06708|VAC14_YEAST Vacuole morphology and inheritance protein 14
OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VAC14 PE=1
SV=1
Length = 880
Score = 153 bits (385), Expect = 8e-036
Identities = 109/394 (27%), Positives = 196/394 (49%), Gaps = 17/394 (4%)
Frame = -2
Query: 1792 SVDYGRMAEILVQRAASPDEFTRWTAITWIYEFVKLGGDQLVPYYADILGAILPCIADKE 1613
++++ + +LV AS + + A+ WI + + + +P+ + IL +L ++D +
Sbjct: 387 NLNFPEVITVLVNNLASSEAEIQLIALHWIQVILSISPNVFIPFLSKILSVLLKLLSDSD 446
Query: 1612 EKIRVVACETNEELLAIKAD----PAEG-FDVGAILSIVKRQLSSEYEATRIESLHWIST 1448
I +A N +LL++ + +G G I++ + Q +I L W+
Sbjct: 447 PHITEIAQLVNGQLLSLCSSYVGKETDGKIAYGPIVNSLTLQFFDSRIDAKIACLDWLIL 506
Query: 1447 LLNRHRTEVLSFLNDIFDTLLKALSDPSDQVVLLVLEVHACIAEDQYN--FRQLVIFLVH 1274
+ ++ ++L + +F TLLK+LS+ ++ L + + D + RQ + L+
Sbjct: 507 IYHKAPNQILKHNDSMFLTLLKSLSNRDSVLIEKALSLLQSLCSDSNDNYLRQFLQDLLT 566
Query: 1273 KFRTDDVLLEKRGPLIIRRLCVLIDAERVYRELSTILEGEADLGFASTMVQALNLILLTS 1094
F+ D L++ R I+R++ + ERVY+ +S+IL+ D F M+Q L+ L+TS
Sbjct: 567 LFKRDTKLVKTRANFIMRQISSRLSPERVYKVISSILDNYNDTTFVKMMIQILSTNLITS 626
Query: 1093 SELSDIRNLLKLSLVNAAGKDFFLXXXXXXXXXXXXXXXLCLLAQAYQHASSVIQSLTEE 914
E+S +RN L+ FF LC +A+ Y+ A +V+Q+
Sbjct: 627 PEMSSLRNKLR----TCEDGMFFNSLFKSWCPNPVSVISLCFVAENYELAYTVLQTYANY 682
Query: 913 DINVIFLVQLDKFIHLLETPIFAYLRLQLLEPGRYTWLLKALYGLIMLLPQQSTAFKILR 734
++ + LVQLD I L E+P+F +RLQLLE ++ +L K L+G++M++P QS AF+ L
Sbjct: 683 ELKLNDLVQLDILIQLFESPVFTRMRLQLLEQQKHPFLHKCLFGILMIIP-QSKAFETLN 741
Query: 733 TRLK-----TVPSYSFNKEQIQRTSSGNPSTETD 647
RL T SY N QR +S + +D
Sbjct: 742 RRLNSLNIWTSQSYVMNNYIRQRENSNFCDSNSD 775
Score = 145 bits (365), Expect = 2e-033
Identities = 72/143 (50%), Positives = 102/143 (71%), Gaps = 2/143 (1%)
Frame = -2
Query: 2467 KNAAIEVEGIVKQLTAAGDHDKITSVINLLTHDFTYS-PQINYRKGGLIGLAAATVGLSA 2291
K AA+E+E +VKQ GD+D+I +I+ L D+ Y+ Q R GL+GLAA + L
Sbjct: 18 KAAALELEKLVKQCVLEGDYDRIDKIIDELCRDYAYALHQPMARNAGLMGLAATAIALGI 77
Query: 2290 -EAAQHLEQILPPVINSFSDQDSRVRYYACEALYNIAKVVRGEFIFHFNKIFDALCKLSA 2114
+ ++L ILPPV+ F DQ+ +VR+YACE+LYNIAK+ +GE + +FN+IFD LCK+SA
Sbjct: 78 NDVGRYLRNILPPVLACFGDQNDQVRFYACESLYNIAKIAKGEILVYFNEIFDVLCKISA 137
Query: 2113 DSDPNVQSAAHLLDRLVKDIVTE 2045
D++ +V+ AA LLDRL+KDIV E
Sbjct: 138 DTENSVRGAAELLDRLIKDIVAE 160
Database: Uniprot/SwissProt
Posted date: Thu Sep 27 17:53:50 2012
Number of letters in database: 190,795,139
Number of sequences in database: 537,505
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,604,837,051
Number of Sequences: 537505
Number of Extensions: 92604837051
Number of Successful Extensions: 530628254
Number of sequences better than 0.0: 0
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